Results 41 to 50 of about 863,145 (246)

Comparative micromorphology and anatomy of flowers and floral secretory structures in two Viburnum species [PDF]

, 2016
In entomogamous plants, the presence and function of floral secretory structures, whose main role is to attract pollinators, is strictly associated with the pollination ecology and hence the reproductive success of the plant.
Agata Konarska
core   +1 more source

Reprogramming M2b Macrophages via GPX1 Activation by Selenium Nanoparticles Attenuates Lupus Nephritis

Advanced Science, EarlyView.
SeZM NPs selectively target M2b macrophages through mannose–MRC1 (CD206) recognition, enhance GPX1 biosynthesis, and suppress mitochondrial ROS generation, oxidative stress, and JAK–STAT signaling. This dual regulation reduces pro‐inflammatory cytokine release, limits immune cell infiltration and fibrosis, and preserves renal function, providing a ...
Haoran Lv, Guanning Huang, Hongyu Li, Hanzhi Liang, Huajing Peng, Kefei Wu, Wenfang Chen, Dandan Zhang, Kexin Ma, Yufei Du, Siweier Luo, Yi Zhou, Haiping Mao, Wei Chen, Tianfeng Chen, Yiming Zhou, Qinghua Liu   +16 more
wiley   +1 more source

Polydatin alleviates mitochondrial damage and apoptosis of lung epithelial cells by inhibiting toll‐like receptor 4‐dependent macrophage activation in asthma

Animal Models and Experimental Medicine, EarlyView.
The alleviation of asthma by polydatin is dependent on the blockage of the toll‐like receptor 4 (TLR4)/P2X7R synergy in macrophages. The blockage of the TLR4/P2X7R synergy results in decreased release and secretion of interleukin‐1β (IL‐1β) and IL‐18. In epithelial cells, low IL‐1β and IL‐18 levels inhibit mitochondrial damage and apoptosis.
Guangxing Li, Ruobai Liu, Chang Xu, Jianing Yang, Yilan Song, Li Li, Jingzhi Jiang, Liangchang Li, Chongyang Wang, Guanghai Yan   +9 more
wiley   +1 more source

Arfgef1 haploinsufficiency in mice alters neuronal endosome composition and decreases membrane surface postsynaptic GABAA receptors [PDF]

, 2019
ARFGEF1 encodes a guanine exchange factor involved in intracellular vesicle trafficking, and is a candidate gene for childhood genetic epilepsies. To model ARFGEF1 haploinsufficiency observed in a recent Lennox Gastaut Syndrome patient, we studied a ...
Allen, Andrew S, Amador, Ariadna, Bartolini, Francesca, Beal, Jules, Frankel, Wayne N, Haut, Sheryl R, Kanber, Ayla, Pero, Maria Elena, Petri, Sabrina, Subramanian, Narayan, Teoh, Jiajie, Williams, Damian, Yang, Mu   +12 more
core   +1 more source

Recombinant Monoclonal Antibodies for Detecting the Tubulin Post‐Translational Modifications Glutamylation and Lysine‐40 Acetylation

Cytoskeleton, EarlyView.
ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius, Ezekiel C. Thomas, Erik H. Collet, Erin Jenson, Chad G. Pearson, Ryoma Ohi, Kristen J. Verhey   +6 more
wiley   +1 more source

Sacubitril/valsartan preserves regional cardiac function following myocardial infarction in rats

ESC Heart Failure, Volume 12, Issue 2, Page 1304-1315, April 2025.
Parts of the figure were drawn by using pictures from Servier Medical Art. Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License (https://creativecommons.org/licenses/by/3.0/). Abstract Aims Sacubitril/valsartan (Sac/Val) is used for treatment of heart failure. The effect of Sac/Val on regional dysfunction
Einar Sjaastad Nordén, Bård Andre Bendiksen, Kaja Knudsen Bergo, Emil Knut Stenersen Espe, Gary McGinley, Almira Hasic, Ida Marie Hauge‐Iversen, Hege Katrin Ugland, Xin Shen, Michael Frisk, Nishani S. Mabotuwana, William E. Louch, Rizwan I. Hussain, Lili Zhang, Ivar Sjaastad, Alessandro Cataliotti, Geir Christensen   +16 more
wiley   +1 more source

A Simple, Ultrastable, and Cost‐Effective Oxygen‐Scavenging System for Long‐Term DNA‐PAINT Imaging

Small, EarlyView.
A simple, enzyme‐free, and cost‐effective oxygen scavenging system enhances DNA‐PAINT super‐resolution microscopy by increasing photostability, minimizing docking strand degradation, and enabling faster, high‐precision localizations. Its long‐term stability supports extended imaging, yielding improved spatial resolution and image quality.
Rebecca T. Perelman, George M. Church, Johannes Stein   +2 more
wiley   +1 more source

Human immunodeficiency virus infection of the human thymus and disruption of the thymic microenvironment in the SCID-hu mouse. [PDF]

, 1993
Infection with the human immunodeficiency virus (HIV) results in immunosuppression and depletion of circulating CD4+ T cells. Since the thymus is the primary organ in which T cells mature it is of interest to examine the effects of HIV infection in this ...
Adelsberger, J, Baseler, M, Bonyhadi, M, Boone, E, Justement, JS, Kaneshima, H, McCune, JM, Orenstein, J, Stanley, SK, Sullivan, M   +9 more
core  

Bionic nanobombs target nasopharyngeal carcinoma to enhance the efficacy of chemoradiotherapy by destroying DNA damage repair systems

VIEW, EarlyView.
A bionic nanomedicine system with core–shell structure (Nm‐pAu/CP/KU) was constructed. PEGylated gold nanoparticles (pAu) were loaded with cisplatin (CP) and a radiochemotherapy sensitizer (KU‐60019) to form the core pAu/CP/KU, and homologous nasopharyngeal carcinoma cell membrane vesicles (Nm) were used as the shell.
Junhua Zhang, Xinying Xiang, Xinmin Nie, Jian Li, Rong Gui   +4 more
wiley   +1 more source

Fabricating intimacy : reading the dressing room in Victorian literature [PDF]

, 2013
The Victorian novel is dominated by heroines, its narrative driven by their impulses and their irrepressible physicality. These women possess a strong visual presence that is intrinsically bound with the way in which they choose to dress themselves, with
Braddon, Brontë, Chico, Cosslett, Craik, Davidoff, Eliot, Eliot, Ellis, Franklin, Freedgood, Gaskell, Gaskell, Gaskell, Girouard, Gorham, Kim, Kortsch, Kunzle, Logan, Maynard, Michelle, Murray, Nash, Oliphant, Oulton, Parker, Reynolds, Tara Puri, Tennyson   +29 more
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