Results 21 to 30 of about 6,022 (216)

The bacterial protein azurin impairs invasion and FAK/Src signaling in P-cadherin-overexpressing breast cancer cell models. [PDF]

PLoS ONE, 2013
P-cadherin overexpression occurs in about 30% of all breast carcinomas, being a poor prognostic factor for breast cancer patients. In a cellular background of wild-type E-cadherin, we have previously shown that its expression promotes invasion, motility ...
Nuno Bernardes, Ana Sofia Ribeiro, Sofia Abreu, Bruna Mota, Rute G Matos, Cecilia M Arraiano, Raquel Seruca, Joana Paredes, Arsenio M Fialho   +8 more
doaj   +1 more source

Conformational substates in azurin. [PDF]

Proceedings of the National Academy of Sciences, 1992
Azurin is a small blue copper protein in the electron transfer chain of denitrifying bacteria. It forms a photolabile complex with nitric oxide (NO) at low temperatures. We studied the temperature dependence of the ligand binding equilibrium and the kinetics of the association reaction after photodissociation over a wide range of temperature (80-280 K)
Ehrenstein, D., Nienhaus, G. U.
openaire   +3 more sources

Recent Advances in Understanding the Electron Transport Through Metal-Azurin-Metal Junctions

Frontiers in Physics, 2022
Azurin proteins are the workhorse of protein electronics. This is a branch of biomolecular electronics, a recent research field which investigates electronics based on biomolecules such as proteins, peptides, amino acids, bacterial nanowires or DNA.
C. Romero-Muñiz, J. G. Vilhena, J. G. Vilhena, R. Pérez, R. Pérez, J. C. Cuevas, J. C. Cuevas, L. A. Zotti, L. A. Zotti   +8 more
doaj   +1 more source

Azurin for Biomolecular Electronics: a Reliability Study [PDF]

Japanese Journal of Applied Physics, 2005
The metalloprotein azurin, used in biomolecular electronics, is investigated with respect to its resilience to high electric fields and ambient conditions, which are crucial reliability issues. Concerning the effect of electric fields, two models of different complexity agree indicating an unexpectedly high robustness.
Bramanti A, Pompa, PP, Maruccio G, Calabi F, Arima V, Cingolani R, Corni S, Di Felice R, De Rienzo F, Rinaldi, R   +11 more
openaire   +5 more sources

Photoinduced Electron Transfer from the Tryptophan Triplet State in Zn-Azurin

, 2022
Tryptophan is one of few residues that participates in biological electron transfer reactions. Upon substitution of the native Cu2+ center with Zn2+ in the blue-copper protein azurin, a long-lived tryptophan neutral radical can be photogenerated.
Joel J. Rivera (6988418), Christina Trinh (14191099), Judy E. Kim (49937)   +2 more
core   +1 more source

Conditioned Medium From Azurin-Expressing Human Mesenchymal Stromal Cells Demonstrates Antitumor Activity Against Breast and Lung Cancer Cell Lines

Frontiers in Cell and Developmental Biology, 2020
Recently, cell-based therapies have been explored as a strategy to enhance the specificity of anticancer therapeutic agents. In this perspective, human mesenchymal stromal cells (MSC) hold a promising future as cell delivery systems for anticancer ...
Marília Silva, Gabriel Amaro Monteiro, Arsenio M. Fialho, Nuno Bernardes, Cláudia Lobato da Silva   +4 more
doaj   +1 more source

Reversible S-nitrosylation in an engineered azurin [PDF]

Nature Chemistry, 2016
S-Nitrosothiols are known as reagents for NO storage and transportation and as regulators in many physiological processes. Although the S-nitrosylation catalysed by haem proteins is well known, no direct evidence of S-nitrosylation in copper proteins has been reported.
Shiliang Tian, Jing Liu, Ryan E. Cowley, Parisa Hosseinzadeh, Nicholas M. Marshall, Yang Yu, Howard Robinson, Mark J. Nilges, Ninian J. Blackburn, Edward I. Solomon, Yi Lu   +10 more
openaire   +2 more sources

Anticancer activity of Pseudomonas aeruginosa derived peptide with iRGD in colon cancer therapy [PDF]

Iranian Journal of Basic Medical Sciences, 2023
Objective(s): Colon cancer is well-known as a life-threatening disease. Since the current treatment modalities for this type of cancer are powerful yet face some limitations, finding novel treatments is required to achieve better outcomes with fewer side
Atieh Yaghoubi, Aref Movaqar, Fereshteh Asgharzadeh, Mohammad Derakhshan, Kiarash Ghazvini, Seyed Mahdi Hasanian, Amir Avan, Asma Mostafapour, Majid Khazaei, Saman Soleimanpour   +9 more
doaj   +1 more source

The Azurin-Derived Peptide CT-p19LC Exhibits Membrane-Active Properties and Induces Cancer Cell Death

Biomedicines, 2021
Peptides have been thoroughly studied as new therapeutic strategies for cancer treatment. In this work, we explored in vitro the anticancer potential of three novel peptides derived from the C-terminal of azurin, an anticancer bacterial protein produced ...
Ana Rita Garizo, Lígia F. Coelho, Sandra Pinto, Tiago P. Dias, Fábio Fernandes, Nuno Bernardes, Arsénio M. Fialho   +6 more
doaj   +1 more source

Corporate social responsibility impact on talent retention among Generation Y [PDF]

REGE Revista de Gestão, 2020
Purpose – As the new emerging workforce, Generation Y (Gen Y) is said to be demanding, influential and possessing strong bargaining power. This study examines the impact of corporate social responsibility (CSR) on employee retention among Gen Y in the ...
Intan Azurin Zainee, Fadilah Puteh
doaj   +1 more source