Results 61 to 70 of about 6,022 (216)

Amyloid Peptide Nanofibrils Promote Efficient Neurotransmitter Oxidation and Serve as Scaffolds for Melanin Production

open access: yesAngewandte Chemie, Volume 137, Issue 44, October 27, 2025.
Short amyloid peptides can act as efficient catalysts of neurotransmitter degradation, and libraries of short peptides can be used to identify core fragments present in larger proteins that might be linked to neurodegenerative diseases. Abstract We have shown that de novo designed peptides self‐assemble in the presence of copper to create ...
Inhye Kim   +5 more
wiley   +2 more sources

Studying the Incidence of Pseudomonas Species as A Causative Agent of Otitis in Iraqi Patients

open access: yesAl-Mustansiriyah Journal of Pharmaceutical Sciences, 2014
Otitis can affect the inner or outer parts of the ear. Some times it is difficult in a rapid response to the treatment. The condition is classified according to occured suddenly for a short time (acute) or repeatedly over a long period of time (chronic).
Dawood Salim Edan, Nahi Yousif Yaseen
doaj   +1 more source

Timing of aneurysm treatment in subarachnoid hemorrhage and grade of functional capacity at discharge: a retrospective cohort study

open access: yesThe Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2023
Background Aneurysmal subarachnoid hemorrhage (SAH) is a vascular pathology with high morbidity and mortality that requires timely management to reduce the risk of complications. However, the ideal time for aneurysm clipping is still controversial.
Adrian Loconi-Vallejos   +3 more
doaj   +1 more source

ASH: A Multi‐Scale, Multi‐Theory Modeling Program

open access: yesJournal of Computational Chemistry, Volume 47, Issue 8, 30 March 2026.
ASH is a Python‐based computational chemistry software for multi‐scale and multi‐theory computations (including QM/MM and ONIOM) and MD simulations. The program is designed for flexible workflows of molecular and biomolecular systems, allowing geometry optimizations, numerical frequencies, high‐level thermochemistry, MD and free‐energy simulations, NEB
Ragnar Bjornsson
wiley   +1 more source

Nitrite Reductase Activities of Azurin Variants [PDF]

open access: yes, 2015
University of Minnesota M.S. thesis.August 2015. Major: Chemistry. Advisor: Steven Berry. 1 computer file (PDF); xi, 113 pages.Nitrite reductase (NiR) catalyzes the reduction of nitrite to nitric oxide in the denitrification stage of nitrogen cycle. To
Khatiwada, Balabhadra
core  

Toward Cancer Diagnostics of the Tumor Suppressor p53 by Surface Enhanced Raman Spectroscopy

open access: yesSensors, 2020
The tumor suppressor p53 protein plays a crucial role in many biological processes. The presence of abnormal concentrations of wild-type p53, or some of its mutants, can be indicative of a pathological cancer state.
Anna Rita Bizzarri   +1 more
doaj   +1 more source

The amino acid sequence of Pseudomonas fluorescens azurin [PDF]

open access: yesBiochemical Journal, 1964
The amino acid sequence of Pseudomonas fluorescens azurin has been determined. The protein consists of a single peptide chain of 128 residues. There is one intra-chain disulphide bridge. The sequence was determined by isolation of the soluble tryptic peptides, and by exhaustive examination of the products of chymotryptic and peptic digestion.
R P, AMBLER, L H, BROWN
openaire   +3 more sources

Intratumoral bacteria engineered for tumor therapy

open access: yesInterdisciplinary Medicine, Volume 4, Issue 2, March 2026.
This article comprehensively reviews engineered intratumoral bacteria used in tumor therapy. The concept development, characteristics, and engineering methods of intratumoral bacteria are summarized. The mechanisms and the translational significance by which engineered intratumoral bacteria interfere with tumor progression are discussed and highlighted.
Huajie Zhang   +7 more
wiley   +1 more source

BIOINFORMATIC STUDY OF AN ANTITUMOR PROTEIN, AZURIN

open access: yes, 2018
Objective: The main objective of this study is to analyze the structure and function of an antitumor protein, azurin, thereby giving validation to the protein structure and existing physicochemical properties in the anticancer protein which are ...
T, Mythili   +3 more
core   +1 more source

Spin‐Density Distribution in the Copper Site of Azurin

open access: yesChemPhysChem, 2006
AbstractA 95 GHz pulsed deuterium ENDOR study has been performed on single crystals of azurin from Pseudomonas aeruginosa selectively deuterated at the Cβ position of the copper‐coordinating cysteine 112. Complete hyperfine tensors of the two deuterium atoms have been obtained, which reveal identical isotropic parts.
Fittipaldi, M.   +7 more
openaire   +3 more sources

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