Results 81 to 90 of about 6,022 (216)

Bacterial Carriers for Glioblastoma Therapy

open access: yesMolecular Therapy: Oncolytics, 2017
Treatment of aggressive glioblastoma brain tumors is challenging, largely due to diffusion barriers preventing efficient drug dosing to tumors. To overcome these barriers, bacterial carriers that are actively motile and programmed to migrate and localize
Nalini Mehta   +5 more
doaj   +1 more source

Hard‐Wired Solid‐State Bioelectronic Micropore Devices: Permanent Metal‐Protein‐Metal Junction Proof‐of‐Concept

open access: yesSmall, Volume 21, Issue 49, December 10, 2025.
A bottom‐up way to fabricate precisely engineered micropore solid‐state metal substrate/protein film / evaporated metal structures is shown to be a versatile platform for systematic electron transport measurements. As protein function is preserved and the junctions are thermally stable, down to 10K, such junctions can be useful for bioelectronic ...
Sudipta Bera   +12 more
wiley   +1 more source

Examining Photoinduced Energy Transfer in Pseudomonas aeruginosa Azurin

open access: yes, 2016
Pseudomonas aeruginosa azurin has been an important model system for investigating fundamental electron transfer (EleT) in proteins. Early pioneering studies used ruthenium photosensitizers to induce EleT in azurin and this experimental data continues to
Peter H. Tobin (1850764)   +1 more
core   +1 more source

The mechanics-modulated tunneling spectrum and low-pass effect of viscoelastic molecular monolayer

open access: yesAIP Advances, 2017
Understanding the force-induced conductance fluctuation in molecules is essential for building molecular devices with high stability. While stiffness of molecule is usually considered to be desirable for stable conductance, we demonstrate mechanical ...
Yun Chen   +5 more
doaj   +1 more source

Artificial Enzymatic Electrochemistry

open access: yesChemElectroChem, Volume 12, Issue 21, November 3, 2025.
Artificial enzymatic electrochemistry has emerged as an effective method to extend the catalytic abilities of enzymes. This review explores the bioelectrochemical methods used to understand and optimize the structure and function of artificial enzymes.
Nya E. Black   +3 more
wiley   +1 more source

Cytotoxic and Morphological Analysis of Azurin and Paclitaxel-Induced Apoptosis against Breast Cancer Cell line

open access: yes, 2023
Azurin is a cupredoxin produced by bacteria that is mostly utilized in electron transport processes. The anticancer properties of the Azurin and its potential use in cancer treatments have increased interest recently.
Asmaa Q. Jebur   +2 more
core   +1 more source

Engineering Bacteria as Living Therapeutics in Cancer Therapy

open access: yesAdvanced Science, Volume 12, Issue 42, November 13, 2025.
Through synthetic biology approaches, natural bacteria can be genetically programmed into multifunctional living therapeutics. These engineered bacteria are capable of secreting anti‐tumor factors, displaying tumor‐associated antigens on their surface, or undergoing programmed self‐lysis to release therapeutic cargo.
Jiangfeng Chen   +6 more
wiley   +1 more source

Molecular screening and genetic diversity analysis of anticancer Azurin-encoding and Azurin-like genes in human gut microbiome deduced through cultivation-dependent and cultivation-independent studies

open access: yes, 2019
Azurin, a bacteriocin produced by a human gut bacterium Pseudomonas aeruginosa, can reveal selectively cytotoxic and induceapoptosis in cancer cells. After overcoming two phase I trials, a functional region of Azurin called p28 has been approved as adrug
Le, Chi Hieu   +5 more
core   +1 more source

Anticancer Activity of Bacterial Proteins and Peptides

open access: yesPharmaceutics, 2018
Despite much progress in the diagnosis and treatment of cancer, tumour diseases constitute one of the main reasons of deaths worldwide. The side effects of chemotherapy and drug resistance of some cancer types belong to the significant current ...
Tomasz M. Karpiński, Artur Adamczak
doaj   +1 more source

Characterization and crystal structure of zinc azurin, a by-product of heterologous expression in Escherichia coli of Pseudomonas aeruginosa copper azurin

open access: yes, 1992
Azurin*, a by-product of heterologous expression of the gene encoding the blue copper protein azurin from Pseudomonas aeruginosa in Escherichia coli, was characterized by chemical analysis and electrospray ionization mass spectrometry, and its structure ...
Barth, M.   +7 more
core   +1 more source

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