Results 51 to 60 of about 64,978 (265)
American Journal of Hematology, EarlyView.ABSTRACT Cardiovascular adverse events (CVAEs) associated with bispecific T‐cell engaging antibodies (BsAbs) have not been systematically investigated across approved agents. In this disproportionality analysis of FAERS (December 2014–September 2025), reports listing BsAbs as the primary suspected drug (n = 7647) were compared with all other drugs in ...
Malak Munir +9 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective Rituximab, a CD20+ B cell depletion therapy, is frequently used to treat systemic lupus erythematosus (SLE). However, variability in patient response highlights the need for a deeper understanding of the underlying immune cell dynamics of B cell depletion and repopulation.
Haerin Jang +9 more
wiley +1 more source
MicroRNA dysregulation in B-cell non-Hodgkin lymphoma
Blood and Lymphatic Cancer: Targets and Therapy, 2013 Emilia L Lim,1 Marco A Marra1,21Canada’s Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, BC, Canada; 2Department of Medical Genetics, University of British Columbia, Vancouver, BC, CanadaAbstract: B-cell non-Hodgkin lymphomas ...
Lim EL, Marra MA
doaj
Haematologica, 2018 Inflammation and B-cell hyperactivation have been associated with non-Hodgkin lymphoma development. This prospective analysis aimed to further elucidate pre-diagnosis plasma immune marker profiles associated with non-Hodgkin lymphoma risk.
Mara M. Epstein +11 more
doaj +1 more source
Aberrant synaptophysin expression in classic Hodgkin lymphoma
Diagnostic Pathology, 2022 Background Synaptophysin is an immunohistochemical marker for neuroendocrine differentiation and is widely used in pathologic diagnosis. Its expression in malignant lymphoma has not yet been described.
Soyoung Im +3 more
doaj +1 more source
Distinct Molecular Pathways Supporting Sjögren Disease Clusters and Disease Progression
Arthritis &Rheumatology, EarlyView.Objective Sjögren disease (SjD) is a heterogeneous autoimmune disease. We aimed to investigate blood transcriptomic signatures and disease progression among three recently defined clusters of patients with SjD: (1) B cell active disease with low symptom burden (BALS), (2) high systemic activity (HSA), and (3) low systemic activity with high symptom ...
Sacha E. Silva‐Saffar +6 more
wiley +1 more source
Primary Extranodal Non-Hodgkin Lymphomas: A First Tertiary Care Experience from Punjab, North India
South Asian Journal of Cancer, 2020 Background Primary extranodal lymphomas are less frequently encountered and difficult to diagnose in routine practice. The histopathological and immunohistochemical studies are essential in addition to clinical details to diagnose.
Vikram Narang +6 more
doaj +1 more source
Peripheral Blood DNA Methylation Changes Precede Lymphoma Diagnosis in Primary Sjögren's Disease
Arthritis &Rheumatology, EarlyView.Objective Primary Sjögren's disease (SjD) is a systemic autoimmune disease associated with an increased risk of lymphoma. The molecular mechanisms underlying lymphomagenesis remain poorly understood, and sensitive biomarkers for early identification of patients at high risk of developing lymphoma are lacking.
Hanna Lidberg +2 more
wiley +1 more source
Indian Journal of Pathology and Microbiology, 2017 Composite lymphoma is a rare tumor composed of two or more distinct lymphomas in the same topographic site or tissue. Several combinations of B-cell non-Hodgkin lymphoma (NHL), T-cell NHL, and Hodgkin lymphoma can occur with different prognoses and ...
Meyyappa Devan Rajagopal +3 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis +5 more
wiley +1 more source