Results 61 to 70 of about 64,978 (265)

Relationship between continuous infusion meropenem PK/PD target attainment and C‐reactive protein dynamics in onco‐haematologic patients with febrile neutropenia

British Journal of Clinical Pharmacology, EarlyView.
Aim Meropenem is a second‐line antimicrobial agent in the treatment of febrile neutropenia in onco‐haematological patients. A population pharmacokinetic/pharmacodynamic (PK/PD) analysis for assessing the relationship between meropenem exposure and C‐reactive protein (C‐RP) over time was conducted.
Chun Liu, Pier Giorgio Cojutti, J. G. Coen van Hasselt, Michele Bartoletti, Maddalena Giannella, Pierluigi Zinzani, Pierluigi Viale, Federico Pea   +7 more
wiley   +1 more source

A Case of Composite Lymphoma with Coexisting Papillary and Medullary Thyroid Carcinomas in a Patient with a History of Four Primary Malignancies

Namık Kemal Tıp Dergisi
Composite lymphoma refers to the simultaneous presence of two or more morphologically and immunophenotypically distinct lymphomas within the same tissue or organ. While cases of composite lymphoma consisting of classical Hodgkin lymphoma (cHL) and B-cell
Zehra AKŞİT BOZKINA, Ajda GÜNEŞ, Derya DEMİR, Mine HEKİMGİL, Nur SOYER, Filiz VURAL   +5 more
doaj   +1 more source

Utilization of immune checkpoint inhibitors for the treatment of cancer in Scotland, 2018–2024: A national retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aims The aim of the study is to describe the use of immune checkpoint inhibitors (ICIs) for the treatment of cancer in Scotland. Methods The retrospective observational cohort study included patients aged 18 years or older who commenced treatment with an ICI in Scotland between 1 January 2018 and 31 December 2024.
Tanja Mueller, Christine Crearie, Liya Lu, Jiafeng Pan, Fraser N. Sneden, David Martin, Amanj Kurdi, Catherine S. Thomson, Julie Clarke, Marion Bennie   +9 more
wiley   +1 more source

Pathophysiology and molecular aspects of diffuse large B-cell lymphoma

Revista Brasileira de Hematologia e Hemoterapia, 2012
Diffuse large B-Cell lymphoma is the most common subtype of non-Hodgkin lymphoma in the West. In Brazil, it is the fifth cause of cancer, with more than 55,000 cases and 26,000 deaths per year.
Gisele Rodrigues Gouveia, Sheila Aparecida Coelho Siqueira, Juliana Pereira   +2 more
doaj  

The outcome of B-cell Non-Hodgkin's lymphoma in children treated with modified UKCCSG FAB LMB 96 protocol: A single center experience

Baghdad Journal of Biochemistry and Applied Biological Sciences
Introduction: Non-Hodgkin lymphoma (NHL) results from the malignant proliferation of cells of lymphocytic lineage. Aim: To asses outcome of B-cell Non-Hodgkin ’s lymphoma in children treated with modified FAB LMB 96 protocol.
Shahad Ali Ahmed AL-Baldawi, Nabeeha Najatee Akram, Zead I. Ibrahim   +2 more
doaj   +1 more source

Retrospective study of canine non-Hodgkin lymphoma cases diagnosed from samples originating in northeastern Brazil (2012-2022) [PDF]

Pesquisa Veterinária Brasileira
: Lymphoma is a malignant hematopoietic neoplasm that affects canines. Its classification is based on anatomical, histomorphological, cytomorphological, and immunophenotypic characteristics.
Saulo R.F. Gonçalves, Dyeime R. Sousa, Ricardo B. Lucena, Lorena G.R. Ribeiro, Rachel L.F.S. Andrade, Daniel A. Viana, Carlos H.C. Vieira-Filho, Silvana M.M.S. Silva, Telma D. Lima, Andrea A.F. Oliveira, Francisco A.L. Souza   +10 more
doaj   +2 more sources

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source

DinoFlow: Self‐supervised pretraining in flow cytometry enables accurate detection of common hematopathological disorders

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Flow cytometry is an essential component of routine hematological lab testing. Many computational methods have been proposed for the analysis of flow cytometry data, but most have focused on supervised learning for just one or a few specific disorders.
Brendan O'Fallon, Muir Morrison, Mattia Medina Grespan, Nicholas C. Spies, David P. Ng   +4 more
wiley   +1 more source

Cardiovascular toxicity induced by TKIs in patients with chronic myeloid leukaemia: Are women and men different?

ESC Heart Failure, Volume 12, Issue 2, Page 1447-1454, April 2025.
This study analyzes 148 patients (66 women and 82 men) with chronic myeloid leukemia treated with tyrosine kinase inhibitors, focusing on cardiovascular adverse events. The risk assessment, performed using the HFA/ICOS score, reveals sex‐specific differences: venous thrombosis is more common in women, while arterial thrombosis predominates in men.
Cristina Madaudo, Daniela Di Lisi, Antonio Cannatà, Federica Manfrè, Celeste Vullo, Marco Santoro, Ciro Botta, Salvatrice Mancuso, Sergio Siragusa, Alfredo Ruggero Galassi, Giuseppina Novo   +10 more
wiley   +1 more source

Non–AIDS‐Defining Cancer Incidence in People With HIV in Milan, Italy, 2000–2023: Temporal Trends and Comparison With the General Population

International Journal of Cancer, EarlyView.
ABSTRACT People with HIV (PWH) are living longer, but contemporary data on non–AIDS‐defining cancers (NADCs) in Italy remain limited. We assessed incident cancers in a retrospective cohort of PWH in Milan, Italy, between January 2000 and December 2023. Follow‐up was grouped into 2000–2007, 2008–2015, and 2016–2023. Incidence rates (IRs) were calculated
Giacomo Pozza, Maddalena Matone, Letizia Oreni, Giorgia Carrozzo, Beatrice Caloni, Maria Vittoria Cossu, Davide Moschese, Anna Lisa Ridolfo, Cristina Gervasoni, Cinzia Fasola, Nicla La Verde, Davide Dalu, Spinello Antinori, Andrea Gori, Andrea Giacomelli   +14 more
wiley   +1 more source