Results 1 to 10 of about 32,904 (275)

Genetic diversity of b-glucuronidase activity among 14 strains of the dominant human gut anaerobe Ruminococcus gnavus

open access: yesGenetics and Molecular Biology, 2006
Bacterial beta-glucuronidase activity in the gut increases the enterohepatic circulation of toxic compounds and plays a major role in the etiology of colon cancer.
Diane Beaud   +4 more
doaj   +5 more sources

Inhibitory Effect of Coumarins and Isocoumarins Isolated from the Stems and Branches of Acer mono Maxim. against Escherichia coli β-Glucuronidase

open access: yesApplied Sciences, 2022
We isolated eight known secondary metabolites, including two isocoumarins and six coumarins, from the stems and branches of Acer mono Maxim. Their structures were confirmed using nuclear magnetic resonance spectroscopy and by comparing the data to ...
Nguyen Viet Phong   +3 more
doaj   +1 more source

Inhibitory Activity of Bioactive Phloroglucinols from the Rhizomes of Dryopteris crassirhizoma on Escherichia coli β-Glucuronidase: Kinetic Analysis and Molecular Docking Studies

open access: yesMetabolites, 2022
Phloroglucinols—one of the major secondary metabolites in Dryopteris crassirhizoma—exhibit various pharmacological effects, such as antiviral, antioxidant, and antidiabetic activities. This study evaluated 30 phloroglucinols isolated from the rhizomes of
Nguyen Viet Phong   +4 more
doaj   +1 more source

Synthesis of 2-Aminopyrimidine Derivatives and Their Evaluation as β-Glucuronidase Inhibitors: In Vitro and In Silico Studies

open access: yesMolecules, 2022
Currently the discovery and development of potent β-glucuronidase inhibitors is an active area of research due to the observation that increased activity of this enzyme is associated with many pathological conditions, such as colon cancer, renal diseases,
Sarosh Iqbal   +7 more
doaj   +1 more source

EXPRESSION OF B-GLUCURONIDASE FROM AMELANCHIER LAEVIS [PDF]

open access: yesHortScience, 1990
Amelanchier laevis shoots were co-cultured with Agrobacterium tumefaciens carrying the binary vector pBI121, which encodes the B-glucuronidase (GUS) and neomycin phosphotransferase genes. Shoots were then rinsed briefly in liquid MS medium and plated onto culture medium containing carbenicillin. After approximately three months of culture, adventitious
Mark G. Bolyard, Mariam B. Stricklen
openaire   +1 more source

Exploring Enzymatic Hydrolysis of Urine Samples for Investigation of Drugs Associated with Drug-Facilitated Sexual Assault

open access: yesPharmaceuticals, 2023
Analyzing urine is common in drug-facilitated sexual assault cases if the analysis of blood is not optimal. The efficient enzymatic pretreatment of urine is important for cleaving glucuronides and improving the detection of the parent drug.
Kathrine Skov   +4 more
doaj   +1 more source

Stabilization of b-Glucuronidase by Immobilization in Magnetic-Silica Hybrid Supports [PDF]

open access: yesCatalysts, 2020
β-Glucuronidases are a class of enzymes that catalyze the breakdown of complex carbohydrates. They have well documented biocatalytic applications in synthesis, therapeutics, and analytics that could benefit from enzyme immobilization and stabilization.
Sonali Correa   +4 more
openaire   +3 more sources

α-Glucosidase and Bacterial β-Glucuronidase Inhibitors from the Stems of Schisandra sphaerandra Staph

open access: yesPharmaceuticals, 2022
α-Glucosidase (AGS) is a therapeutic target for Type 2 diabetes mellitus (T2DM) that tends to complicate with other diseases. Some medications for the treatment of T2DM complications have the risk of inducing severe adverse reactions such as diarrhea via
Guiwei Rao   +10 more
doaj   +1 more source

Efficient genetic transformation of Lotus corniculatus L. using a direct shoot regeneration protocol, stepwise hygromycin B selection, and a super-binary Agrobacterium tumefaciens vector [PDF]

open access: yesArchives of Biological Sciences, 2007
Cotyledons from 6-day-old Lotus corniculatus cv. Bokor seedlings, transversally cut into two halves, were capa­ble of regenerating buds without intervening callus formation.
Nikolić Radomirka   +3 more
doaj   +1 more source

The iSplit GFP assay detects intracellular recombinant proteins in Bacillus subtilis

open access: yesMicrobial Cell Factories, 2021
Background Bacillus subtilis is one of the most important microorganisms for recombinant protein production. It possesses the GRAS (generally recognized as safe) status and a potent protein secretion capacity.
Patrick Lenz   +9 more
doaj   +1 more source

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