Results 91 to 100 of about 779,870 (354)

Estudo dos linfócitos T CD4, CD8 e B em pacientes com narcolepsia [PDF]

, 2007
Narcolepsy is characterized by excessive daytime sleep and cataplexy. Little is known about the possible difference in pathophysiology between patients with or without cataplexy.
Alves, Gabriela Rodrigues, Bittencourt, Lia Rita Azeredo, Coelho, Fernando Morgadinho Santos, Moreira, Fábio, Pedrazzoli, Mario, Pradella-Hallinan, Márcia Lurdes de Cássia, Tufik, Sergio   +6 more
core   +3 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

New immunolatex spheres: visual markers of antigens on lymphocytes for scanning electron microscopy [PDF]

, 1975
New immunochemical reagents consisting of antibodies bound to small latex spheres were used as visual markers for the detection and localization of cell surface antigens by scanning electron microscopy.
Dreyer, William J., Molday, Robert S., Rembaum, Alan, Yen, S. P. S.   +3 more
core   +2 more sources

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Overexpression of the p73 gene is a novel finding in high-risk B-cell chronic lymphocytic leukemia [PDF]

, 2017
The p73 protein shares structural and functional similarities with the tumour-suppressor p53, but its role in neoplastic transformation is unknown. Alternative splicing leads to the expression of at least nine p73 C-terminal mRNA splice variants (α β γ δ
Aebi, S., Baskaynak, G., Cajot, J.-F, Fey, M. F., Grob, T. J., Kreuzer, K.-A, Leibundgut, E. Oppliger, Novak, U., Peters, U. R., Tobler, A., Tschan, M. P., Zwahlen, D.   +11 more
core  

CD20 and CD40 mediated mitogenic responses in B-lineage acute lymphoblastic leukaemia [PDF]

, 1996
Activation of CD20, a cross-membrane ion channel, induces cell cycle progression from G0 to G1 in B lymphocytes. Subsequent activation of CD40, a membrane receptor of the nerve growth factor receptor superfamily, transits the B cells to the S phase. CD40
Hählen, K. (Karel), Löwenberg, B. (Bob), Paassen, M. (Marleen) van, Smiers, F.J.W. (Frans), Touw, I.P. (Ivo)   +4 more
core   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Pathogenesis-based treatments in primary Sjogren's syndrome using artificial intelligence and advanced machine learning techniques: a systematic literature review

Human Vaccines & Immunotherapeutics, 2018
Big data analysis has become a common way to extract information from complex and large datasets among most scientific domains. This approach is now used to study large cohorts of patients in medicine. This work is a review of publications that have used
Nathan Foulquier, Pascal Redou, Christophe Le Gal, Bénédicte Rouvière, Jacques-Olivier Pers, Alain Saraux   +5 more
doaj   +1 more source

Histological examination of the palatine tonsils in chronic tonsillitis

Медицинский совет, 2019
The article is devoted to the problem of chronic tonsillitis. The aim of the study was to assess changes in the morphofunctional state of the palatine tonsils in chronic inflammation. The study presents comparative data of immunohistochemical examination
V. T. Pal’chun, A. V. Gurov, T. K. Dubovaya, A. G. Ermolaev   +3 more
doaj   +1 more source

RAGs and Regulation of Autoantibodies [PDF]

, 2004
Autoreactive antibodies are etiologic agents in a number of autoimmune diseases. Like all other antibodies these antibodies are produced in developing B cells by V(D)J recombination in the bone marrow.
Casellas, Rafael, Jankovic, Mila, Nussenzweig, Michel C., Wardemann, ­Hedda, Yannoutsos, Nikos   +4 more
core   +1 more source