Results 211 to 220 of about 693,632 (262)

B-Lymphocyte Malignancy

New England Journal of Medicine, 1973
The division of the lymphoid system into two major functionally distinct kinds of cells has increased immensely understanding not only of normal immunity but also of neoplasia affecting these cells. It is now abundantly clear that certain lymphocytes are conditioned by the thymus (hence their designation as T-cells) and acquire the ability to mediate ...
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B lymphocyte activation

Immunology Today, 1981
A review focussing on the lessons learned from polyclonal activation of B cells.
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B-Lymphocytes in Carcinogenesis

1979
Cancer is not a single disease entity; the term is applied to a large number of diseases in which the abnormal and continued growth of cells of a given tissue is expressed. The immunologic mechanism responsible for the rejection of solid tumors in experimental animals is generally thought to be the same as that responsible for homograft rejection, i.e.,
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Antigen Receptors on B Lymphocytes

Annual Review of Immunology, 1992
Recent studies on the structure of the B cell antigen receptor demonstrate that the membrane-bound and antigen-binding immunoglobulin molecules are noncovalently associated with a heterodimer of two novel transmembrane proteins. The B cell antigen receptor is thus a multicomponent receptor complex whose structural features are similar to those of the ...
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Trafficking of Adoptively Transferred B Lymphocytes in B-Lymphocyte-Deficient Mice

Journal of Experimental Biology, 1997
ABSTRACT Many studies have investigated the fate of adoptively transferred lymphocytes in recipient mice, although little is known of the sites where these transferred cells reside at particular time points. Using flow cytometry, we analyzed the trafficking pattern of adoptively transferred naive B cells into the lymphoid organs of ...
R, Roth, M J, Mamula
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Interactions between B lymphocyte subpopulations. Augmentation of the responses of resting B lymphocytes by activated B lymphocytes.

The Journal of Immunology, 1988
Abstract Mouse B lymphocytes were fractionated from normal T lymphocyte-depleted spleen cell populations using discontinuous percoll gradients and were stimulated with rabbit F(ab')2 anti-mouse mu-specific antibodies (anti-mu) plus the supernatant of Con A-stimulated rat spleen cells (SN) as a source of lymphokines.
F, Uher, H B, Dickler
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Activation of Human B Lymphocytes

The Journal of Immunology, 1977
Abstract The kinetics and mechanisms of suppression of the PWM-induced PFC response of human PB lymphocytes by Con A-activated suppressor cells were investigated. It was necessary that Con A suppressor cells be present early in the preocess of activation of human B cells toward antibody synthesis, but maximal suppression of the PFC ...
Barton F. Haynes, Anthony S. Fauci
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Early B lymphocytes in man

Experientia, 1980
We have confirmed in man the presence of a subpopulation of B lymphocytes which cannot reexpress their immunological receptors after challenge with antibodies. These early B lymphocytes were studied in peripheral blood, in cord blood and also, with anti-idiotypic sera, in the peripheral blood of a myeloma patient.
CONTE, PIERFRANCO, M. Boccadoro, A. Pileri   +2 more
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Biochemistry of B Lymphocyte Activation

1993
The activation of B lymphocytes from resting cells proceeds from the events of early activation to clonal proliferation to final differentiation into either an antibody-secreting plasma cell or a memory B cell. This is a complex activation process marked by several alternative pathways, depending on the nature of the initial antigenic stimulus.
M R, Gold, A L, DeFranco
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B LYMPHOCYTES IN MACROGLOBULINÆMIA

The Lancet, 1971
A M, Marmont, E E, Damasio
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