Results 211 to 220 of about 13,971,057 (260)

Correction: Spatial organization of B lymphocytes and prognosis prediction in patients with gastric cancer. [PDF]

Gastric Cancer
Tay RYK, Sachdeva M, Ma H, Kim YW, Kook MC, Kim H, Cheong JH, Hewitt LC, Nekolla K, Schmidt G, Yoshikawa T, Oshima T, Arai T, Srivastava S, Teh M, Ong X, Tay ST, Sheng T, Zhao JJ, Tan P, Grabsch HI, Sundar R.   +21 more
europepmc   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Alternative splicing in the RBMXL1 5'-UTR induces uORF-mediated translation control in activated B lymphocytes. [PDF]

Sci Rep
de Breyne S, Polvèche H, Auboeuf D, Ohlmann T, Gruffat H, Manet E.   +5 more
europepmc   +1 more source

Natural‐Inspired Engineered Microalgae With Selenium Enrichment Enabled Potent Anti‐Tumor Immunity

Advanced Science, EarlyView.
Se‐Ssp was engineered as a potent immunomodulator for activating innate immunity via the TLR and cGAS‐STING pathways, therefore converting “cold” tumors into “hot” tumors to achieve high efficacy and long‐term therapeutic outcomes. ABSTRACT Immunotherapy has shed light on clinical oncology for several decades.
Yuqi Yang, Xiaowei Cai, Xiaoyan Zhong, Tian Qiu, Qinwei Lu, Jiahao Qin, Fei Gong, Yecheng Huang, Chenyu Jiang, Youdong Chen, Yuan Cheng, Liang Cheng   +11 more
wiley   +1 more source

Phenotypic alterations in peripheral blood B Lymphocytes of patients with Alzheimer's Disease. [PDF]

J Prev Alzheimers Dis
Wang MT, Wang YR, Zeng GH, Zeng XQ, Fei ZC, Chen J, Zhou J, Li XP, Xu ZQ, Wang YJ, Liu YH.   +10 more
europepmc   +1 more source

Organic Nanozyme‐Embedded Biotherapeutic Thermosensitive Hydrogel for Extracellular GSH Depletion and Postoperative Tumor Suppression

Advanced Science, EarlyView.
A temperature‐sensitive hydrogel loaded with cyanine nanozymes and Escherichia coli is locally injected into postoperative tumor resection beds. Upon light irradiation, synergistic PTT and PDT work with cascaded reactive oxygen species to deplete extracellular GSH, eliminate residual tumor cells, and induce robust antitumor immune responses for ...
Cong Jiang, Zifan Yang, Rong Guo, Meng Suo, Guowei Wang, Dong Chen, Lilin Su, Fuhuan Wang, Shipeng Ning, Kelong Fan, Xuan Wang   +10 more
wiley   +1 more source

Interleukin-6 accelerates the progression of warm autoimmune hemolytic anemia by affecting the DNA methylation status of peripheral blood B lymphocytes. [PDF]

Sci Rep
Zhao M, Zhang Y, Liu Z, Fu R, Wang H, Shao Z, Xing L.   +6 more
europepmc   +1 more source

Inorganic Nanomaterials can Promote or Inhibit Tumor Metastasis Depending on Tumor Microenvironment Composition

Advanced Science, EarlyView.
As engineered nanomaterials gain prominence in cancer imaging and therapy, understanding their impact on tumor progression becomes increasingly critical. We demonstrate that gold and silica‐coated gold nanomaterials can either suppress or enhance breast cancer metastasis through distinct tumor microenvironment interactions, while identifying ...
Kiana Buttiens, Xiaoqi Zheng, Xueqi Fan, Mukaddes Izci, Christy Maksoudian, Irati Perez Gilabert, Tianjiao Chu, Filipa Goncalves, Jonas Dehairs, Johan Swinnen, Bella B. Manshian, Stefaan J. Soenen   +11 more
wiley   +1 more source

Rescued with T and B lymphocytes depletion therapy for immune checkpoint inhibitor-associated transplant rejection. [PDF]

Immunotherapy
Qiu S, Zong Z, He K.
europepmc   +1 more source