Results 341 to 350 of about 14,119,663 (382)
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CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes.
Science, 1992Lymphocytes must proliferate and differentiate in response to low concentrations of a vast array of antigens. The requirements of broad specificity and sensitivity conflict because the former is met by low-affinity antigen receptors, which precludes ...
R. Carter, D. Fearon
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Antigen Receptors on B Lymphocytes
Annual Review of Immunology, 1992Recent studies on the structure of the B cell antigen receptor demonstrate that the membrane-bound and antigen-binding immunoglobulin molecules are noncovalently associated with a heterodimer of two novel transmembrane proteins. The B cell antigen receptor is thus a multicomponent receptor complex whose structural features are similar to those of the ...
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B-Lymphocytes in Carcinogenesis
1979Cancer is not a single disease entity; the term is applied to a large number of diseases in which the abnormal and continued growth of cells of a given tissue is expressed. The immunologic mechanism responsible for the rejection of solid tumors in experimental animals is generally thought to be the same as that responsible for homograft rejection, i.e.,
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T and B lymphocyte quantitation in children
Irish Journal of Medical Science, 1978T and B-lymphocyte subpopulations in children were quantified using E-rosetting and immunofluorescence techniques respectively. Methanol fixation was used for B-lymphocyte preparations while E-rosettes were examined using conventional techniques. The preparations were stable for days and counts showed a high degree of reproducibility.
P. B. Deasy, A. P. Finch, J. Greally
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T and B Lymphocytes in Atopic Eczema
Archives of Dermatology, 1974Using E and EAC rossette assays, T and B lymphocytes were quantitated in patients with atopic eczema. Adult patients had percentages of T lymphocytes at the lower end of the range of normal. When evaluated as a group, their mean percentage was significantly lower than that of controls. B lymphocytes were present in normal percentages.
John R. Luckasen +3 more
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Archivum immunologiae et therapiae experimentalis, 1981
B lymphocyte markers in 24 full term newborn infants were evaluated within four days after birth. It was demonstrated that the percentage of cells with surface immunoglobulins (SmIg) in the blood of these subjects was normal when the lymphocytes were stained with polyvalent as well as monospecific antisera.
AGOSTINI, CARLO +6 more
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B lymphocyte markers in 24 full term newborn infants were evaluated within four days after birth. It was demonstrated that the percentage of cells with surface immunoglobulins (SmIg) in the blood of these subjects was normal when the lymphocytes were stained with polyvalent as well as monospecific antisera.
AGOSTINI, CARLO +6 more
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Tolerance in differentiating B lymphocytes
European Journal of Immunology, 1977AbstractThese experiments demonstrate that the response of B lymphocytes to particulate antigen in vivo can depend on their stage of differentiation: B lymphocytes differentiating from stem cells were rendered tolerant, while mature B lymphocytes were primed under the same conditions. Lethally irradiated mice of one allotype were repopulated with 13–15
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Signal transduction in B lymphocytes
Human Immunology, 1991We have examined the activity and intracellular compartmentalization of protein kinase C (PKC) following activation of human B lymphocytes by anti-human leukocyte antigen (HLA) class II antibodies. 12-O-Tetradecanoylphorbol 13-acetate (TPA) treatment increased membrane-associated PKC (between five and nine times greater than the control value) and ...
Dominique Charron +2 more
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