Results 141 to 150 of about 30,612,164 (294)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Detecting early kidney allograft fibrosis with multi-b-value spectral diffusion MRI. [PDF]

Sci Rep
Liu MM, Dyke J, Gladytz T, Jasse J, Bolger I, Calle S, Pavuluri S, Crews T, Kimm-Drapeau AL, Seshan S, Salvatore S, Stillman I, Muthukumar T, Taouli B, Farouk S, Bane O, Lewis S.   +16 more
europepmc   +1 more source

Image quality assessment using deep learning in high b-value diffusion-weighted breast MRI. [PDF]

Sci Rep, 2023
Kapsner LA, Balbach EL, Folle L, Laun FB, Nagel AM, Liebert A, Emons J, Ohlmeyer S, Uder M, Wenkel E, Bickelhaupt S.   +10 more
europepmc   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Differentiating Brain Metastasis and High-Grade Glioma Using Multi-b Value Diffusion MRI and Tumor Volumetry. [PDF]

J Neuroimaging
Kopřivová T, Dostál M, Jůza T, Vybíhal V, Ovesná P, Kozubek M, Keřkovský M.   +6 more
europepmc   +1 more source

Accelerating High b-Value Diffusion-Weighted MRI Using a Convolutional Recurrent Neural Network (CRNN-DWI). [PDF]

Bioengineering (Basel), 2023
Zhong Z, Ryu K, Mao J, Sun K, Dan G, Vasanawala SS, Zhou XJ.   +6 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Enhancing prostate cancer detection: The role of b-value and apparent diffusion coefficient in DWI. [PDF]

F1000Res
Goveas B, Dkhar W, Kadavigere R, Nayak K, Pradhan A, Venugopal A, Shastry P, Barnes Abraham N.   +7 more
europepmc   +1 more source

Computed high-b-value high-resolution DWI improves solid lesion detection in IPMN of the pancreas. [PDF]

Eur Radiol, 2023
Harder FN, Jung E, Weiss K, Graf MM, Kamal O, McTavish S, Van AT, Demir IE, Friess H, Phillip V, Schmid RM, Lohöfer FK, Kaissis GA, Makowski MR, Karampinos DC, Braren RF.   +15 more
europepmc   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source