Results 151 to 160 of about 30,612,164 (294)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Corrigendum: Study on the acoustic emission characteristics of different rock types and its fracture mechanism in brazilian splitting test

Frontiers in Physics, 2022
Li Shengxiang, Li Shengxiang, Xie Qin, Liu Xiling, Liu Xiling, Li Xibing, Luo Yu, Chen Daolong   +7 more
doaj   +1 more source

A Study Based on b-Value and Information Entropy in the 2008 Wenchuan 8.0 Earthquake. [PDF]

Entropy (Basel)
Liang S, Wang Z, Wang X.
europepmc   +1 more source

B-value variations in the Central Chile seismic gap assessed by a Bayesian transdimensional approach. [PDF]

Sci Rep, 2022
Morales-Yáñez C, Bustamante L, Benavente R, Sippl C, Moreno M.   +4 more
europepmc   +1 more source

"b value" of diffusion weighted imaging

Tuberkuloz ve Toraks, 2015
openaire   +2 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Virtual contrast-enhanced maximum intensity projections from high-b-value diffusion-weighted breast MRI: a feasibility study. [PDF]

Eur Radiol Exp
Liebert A, Schreiter H, Hadler D, Kapsner LA, Ohlmeyer S, Eberle J, Erber R, Emons J, Laun FB, Uder M, Wenkel E, Bickelhaupt S.   +11 more
europepmc   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

The utility of multi-b-value diffusion and arterial spin labelling magnetic resonance imaging in gliomas grading and prediction of isocitrate dehydrogenase status. [PDF]

Quant Imaging Med Surg
Kopřivová T, Dostál M, Jůza T, Vybíhal V, Neuman E, Ovesná P, Kozubek M, Keřkovský M.   +7 more
europepmc   +1 more source

Dependence on b-value of the direction-averaged diffusion-weighted imaging signal in brain.

Magnetic Resonance Imaging, 2017
Emilie T. McKinnon, J. Jensen, G. Glenn, J. Helpern   +3 more
semanticscholar   +1 more source