Ex Vivo Murine Skin Model for B. burgdorferi Biofilm [PDF]
Antibiotics, 2020 Borrelia burgdorferi, the causative agent of Lyme disease, has been recently shown to form biofilm structures in vitro and in vivo. Biofilms are tightly clustered microbes characterized as resistant aggregations that allow bacteria to withstand harsh ...
Jason P. Torres +5 more
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The cyclic-di-GMP signaling pathway in the Lyme disease spirochete, Borrelia burgdorferi [PDF]
Frontiers in Cellular and Infection Microbiology, 2014 In nature, the Lyme disease spirochete Borrelia burgdorferi cycles between the unrelated environments of the Ixodes tick vector and mammalian host. In order to survive transmission between hosts, B.
Elizabeth A. Novak +2 more
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Activity of Sulfa Drugs and Their Combinations against Stationary Phase B. burgdorferi In Vitro.
Antibiotics (Basel), 2017 Lyme disease is a most common vector borne disease in the US. Although the majority of Lyme patients can be cured with the standard 2-4 week antibiotic treatment, at least 10-20% of patients continue to suffer from prolonged post-treatment Lyme disease ...
Feng J, Zhang S, Shi W, Zhang Y.
europepmc +2 more sources
RNA-Seq of Borrelia burgdorferi in Multiple Phases of Growth Reveals Insights into the Dynamics of Gene Expression, Transcriptome Architecture, and Noncoding RNAs. [PDF]
PLoS ONE, 2016 Borrelia burgdorferi, the agent of Lyme disease, differentially expresses numerous genes and proteins as it cycles between mammalian hosts and tick vectors.
William K Arnold +5 more
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Borrelia burgdorferi Manipulates Innate and Adaptive Immunity to Establish Persistence in Rodent Reservoir Hosts. [PDF]
Frontiers in Immunology, 2017 Borrelia burgdorferi sensu lato species complex is capable of establishing persistent infections in a wide variety of species, particularly rodents. Infection is asymptomatic or mild in most reservoir host species, indicating successful co-evolution of ...
Baumgarth, Nicole, Tracy, Karen E
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Borrelia mayonii induces carditis but not arthritis in Lyme-susceptible mice [PDF]
Frontiers in ImmunologyBackgroundBorrelia mayonii, a Borrelia burgdorferi sensu lato (Bbsl) genospecies, is a cause of Lyme disease in the upper midwestern United States. B.
Dawn W. Cleveland +5 more
doaj +2 more sources
A Dual Luciferase Reporter System for B. burgdorferi Measures Transcriptional Activity during Tick-Pathogen Interactions [PDF]
Frontiers in Cellular and Infection Microbiology, 2017 Knowledge of the transcriptional responses of vector-borne pathogens at the vector-pathogen interface is critical for understanding disease transmission.
Philip P. Adams +2 more
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Borrelia burgdorferi BBK32 Inhibits the Classical Pathway by Blocking Activation of the C1 Complement Complex [PDF]
PLoS Pathogens, 2016 Citation: Garcia, B. L., Zhi, H., Wager, B., Hook, M., & Skare, J. T. (2016). Borrelia burgdorferi BBK32 Inhibits the Classical Pathway by Blocking Activation of the C1 Complement Complex. Plos Pathogens, 12(1), 28.
A Alitalo +101 more
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PLoS ONE, 2023 Colonization of a localized area of human skin by Borrelia burgdorferi after a bite from an infected tick is the first step in the development of Lyme disease.
Berta Victoria +4 more
doaj +1 more source
Borrelia burgdorferi infection modifies protein content in saliva of Ixodes scapularis nymphs
BMC Genomics, 2021 Background Lyme disease (LD) caused by Borrelia burgdorferi is the most prevalent tick-borne disease. There is evidence that vaccines based on tick proteins that promote tick transmission of B. burgdorferi could prevent LD.
Tae Kwon Kim +6 more
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