Ex Vivo Murine Skin Model for B. burgdorferi Biofilm [PDF]
Antibiotics, 2020 Borrelia burgdorferi, the causative agent of Lyme disease, has been recently shown to form biofilm structures in vitro and in vivo. Biofilms are tightly clustered microbes characterized as resistant aggregations that allow bacteria to withstand harsh ...
Jason P. Torres +5 more
doaj +5 more sources
The cyclic-di-GMP signaling pathway in the Lyme disease spirochete, Borrelia burgdorferi [PDF]
Frontiers in Cellular and Infection Microbiology, 2014 In nature, the Lyme disease spirochete Borrelia burgdorferi cycles between the unrelated environments of the Ixodes tick vector and mammalian host. In order to survive transmission between hosts, B.
Elizabeth A. Novak +2 more
doaj +4 more sources
Acta Veterinaria Scandinavica, 2010 Background Borrelia burgdorferi sensu lato (s.l.) are the causative agent for Lyme borreliosis (LB), the most common tick-borne disease in the northern hemisphere.
Skarpaas Tone +3 more
doaj +4 more sources
Borrelia mayonii induces carditis but not arthritis in Lyme-susceptible mice [PDF]
Frontiers in ImmunologyBackgroundBorrelia mayonii, a Borrelia burgdorferi sensu lato (Bbsl) genospecies, is a cause of Lyme disease in the upper midwestern United States. B.
Dawn W. Cleveland +5 more
doaj +2 more sources
A Dual Luciferase Reporter System for B. burgdorferi Measures Transcriptional Activity during Tick-Pathogen Interactions [PDF]
Frontiers in Cellular and Infection Microbiology, 2017 Knowledge of the transcriptional responses of vector-borne pathogens at the vector-pathogen interface is critical for understanding disease transmission.
Philip P. Adams +2 more
doaj +2 more sources
PLoS ONE, 2023 Colonization of a localized area of human skin by Borrelia burgdorferi after a bite from an infected tick is the first step in the development of Lyme disease.
Berta Victoria +4 more
doaj +1 more source
Borrelia burgdorferi infection modifies protein content in saliva of Ixodes scapularis nymphs
BMC Genomics, 2021 Background Lyme disease (LD) caused by Borrelia burgdorferi is the most prevalent tick-borne disease. There is evidence that vaccines based on tick proteins that promote tick transmission of B. burgdorferi could prevent LD.
Tae Kwon Kim +6 more
doaj +1 more source
Effect of Borrelia burgdorferi Outer Membrane Vesicles on Host Oxidative Stress Response
Antibiotics, 2020 Outer membrane vesicles (OMVs) are spherical bodies containing proteins and nucleic acids that are released by Gram-negative bacteria, including Borrelia burgdorferi, the causative agent of Lyme disease. The functional relationship between B. burgdorferi
Keith Wawrzeniak +3 more
doaj +1 more source
Synthesis of RpoS is dependent on a putative enhancer binding protein Rrp2 in Borrelia burgdorferi. [PDF]
PLoS ONE, 2014 The RpoN-RpoS regulatory pathway plays a central role in governing adaptive changes by B. burgdorferi when the pathogen shuttles between its tick vector and mammalian hosts.
Zhiming Ouyang +2 more
doaj +1 more source
RNA-Seq of Borrelia burgdorferi in Multiple Phases of Growth Reveals Insights into the Dynamics of Gene Expression, Transcriptome Architecture, and Noncoding RNAs. [PDF]
PLoS ONE, 2016 Borrelia burgdorferi, the agent of Lyme disease, differentially expresses numerous genes and proteins as it cycles between mammalian hosts and tick vectors.
William K Arnold +5 more
doaj +1 more source