The cyclic-di-GMP signaling pathway in the Lyme disease spirochete, Borrelia burgdorferi
Frontiers in Cellular and Infection Microbiology, 2014 In nature, the Lyme disease spirochete Borrelia burgdorferi cycles between the unrelated environments of the Ixodes tick vector and mammalian host. In order to survive transmission between hosts, B.
Elizabeth A. Novak +2 more
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Borrelia miyamotoi sensu lato Seroreactivity and Seroprevalence in the Northeastern United States
Emerging Infectious Diseases, 2014 Borrelia miyamotoi sensu lato, a relapsing fever Borrelia sp., is transmitted by the same ticks that transmit B. burgdorferi (the Lyme disease pathogen) and occurs in all Lyme disease–endemic areas of the United States. To determine the seroprevalence of
Peter J. Krause +16 more
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Hyperglycemia Impairs Neutrophil-Mediated Bacterial Clearance in Mice Infected with the Lyme Disease Pathogen. [PDF]
PLoS ONE, 2016 Insulin-insufficient type 1 diabetes is associated with attenuated bactericidal function of neutrophils, which are key mediators of innate immune responses to microbes as well as pathological inflammatory processes.
Ashkan Javid +14 more
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An optimized SYBR Green I/PI assay for rapid viability assessment and antibiotic susceptibility testing for Borrelia burgdorferi. [PDF]
PLoS ONE, 2014 Lyme disease caused by Borrelia burgdorferi is the most common tick-borne disease in the US and Europe. Unlike most bacteria, measurements of growth and viability of B. burgdorferi are challenging. The current B.
Jie Feng +4 more
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Frontiers in Veterinary Science, 2021 Cats that spend time outdoors and dogs are particularly at risk of exposure to ticks and the pathogens they transmit. A retrospective study on data collected through passive tick surveillance was conducted to estimate the risk of exposure to tick-borne ...
Lauriane Duplaix +15 more
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Large scale spatial risk and comparative prevalence of Borrelia miyamotoi and Borrelia burgdorferi sensu lato in Ixodes pacificus. [PDF]
PLoS ONE, 2014 Borrelia miyamotoi is a newly described emerging pathogen transmitted to people by Ixodes species ticks and found in temperate regions of North America, Europe, and Asia.
Kerry Padgett +8 more
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Human neuroglial cells internalize Borrelia burgdorferi by coiling phagocytosis mediated by Daam1. [PDF]
PLoS ONE, 2018 Borrelia burgdorferi, the agent of Lyme borreliosis, can elude hosts' innate and adaptive immunity as part of the course of infection. The ability of B. burgdorferi to invade or be internalized by host cells in vitro has been proposed as a mechanism for ...
Shanna K Williams +2 more
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Журнал микробиологии, эпидемиологии и иммунобиологии, 2021 Background. Information on the geographical distribution of different species of the Borrelia burgdorferi sensu lato (B. burgdorferi s.l.) complex is of great epidemiological importance, since different genospecies are associated with certain clinical ...
A. O. Bissenbay +12 more
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Identification of Three Species of Borrelia burgdorferi Sensu Lato (B. burgdorferi Sensu Stricto, B. garinii, and B. afzelii) Among Isolates from Acrodermatitis Chronica Atrophicans Lesions [PDF]
Journal of Investigative Dermatology, 1998 In Europe, at least three species of Borrelia are known to be causative agents of Lyme borreliosis: B. burgdorferi sensu stricto, B. garinii, and B. afzelii. Observable differences in the molecular characteristics of the three species have led to speculation that they may also differ in their pathogenic potential and/or tissue tropisms. Several studies
Picken, Roger N. +6 more
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Optimization of tissue sampling for Borrelia burgdorferi in white-footed mice (Peromyscus leucopus).
PLoS ONE, 2020 Peromyscus leucopus (the white-footed mouse) is a known reservoir of the Lyme disease spirochete Borrelia burgdorferi. Sampling of white-footed mice allows for year-round B.
Sonya G Zawada +4 more
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