Ex Vivo Murine Skin Model for B. burgdorferi Biofilm [PDF]
Antibiotics, 2020 Borrelia burgdorferi, the causative agent of Lyme disease, has been recently shown to form biofilm structures in vitro and in vivo. Biofilms are tightly clustered microbes characterized as resistant aggregations that allow bacteria to withstand harsh ...
Jason P. Torres +5 more
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Borrelia burgdorferi Enolase Is a Surface-Exposed Plasminogen Binding Protein
PLoS ONE, 2011 Borrelia burgdorferi is the causative agent of Lyme disease, the most commonly reported arthropod-borne disease in the United States. B. burgdorferi is a highly invasive bacterium, yet lacks extracellular protease activity.
Catherine A Brissette
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The cyclic-di-GMP signaling pathway in the Lyme disease spirochete, Borrelia burgdorferi
Frontiers in Cellular and Infection Microbiology, 2014 In nature, the Lyme disease spirochete Borrelia burgdorferi cycles between the unrelated environments of the Ixodes tick vector and mammalian host. In order to survive transmission between hosts, B.
Syed Z Sultân, Md A Motaleb
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A Dual Luciferase Reporter System for B. burgdorferi Measures Transcriptional Activity during Tick-Pathogen Interactions [PDF]
Frontiers in Cellular and Infection Microbiology, 2017 Knowledge of the transcriptional responses of vector-borne pathogens at the vector-pathogen interface is critical for understanding disease transmission.
Philip P. Adams +2 more
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PLoS ONE, 2023 Colonization of a localized area of human skin by Borrelia burgdorferi after a bite from an infected tick is the first step in the development of Lyme disease.
Berta Victoria +4 more
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Borrelia burgdorferi infection modifies protein content in saliva of Ixodes scapularis nymphs
BMC Genomics, 2021 Background Lyme disease (LD) caused by Borrelia burgdorferi is the most prevalent tick-borne disease. There is evidence that vaccines based on tick proteins that promote tick transmission of B. burgdorferi could prevent LD.
Tae Kwon Kim +6 more
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Effect of Borrelia burgdorferi Outer Membrane Vesicles on Host Oxidative Stress Response
Antibiotics, 2020 Outer membrane vesicles (OMVs) are spherical bodies containing proteins and nucleic acids that are released by Gram-negative bacteria, including Borrelia burgdorferi, the causative agent of Lyme disease. The functional relationship between B. burgdorferi
Keith Wawrzeniak +3 more
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Synthesis of RpoS is dependent on a putative enhancer binding protein Rrp2 in Borrelia burgdorferi. [PDF]
PLoS ONE, 2014 The RpoN-RpoS regulatory pathway plays a central role in governing adaptive changes by B. burgdorferi when the pathogen shuttles between its tick vector and mammalian hosts.
Zhiming Ouyang +2 more
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RNA-Seq of Borrelia burgdorferi in Multiple Phases of Growth Reveals Insights into the Dynamics of Gene Expression, Transcriptome Architecture, and Noncoding RNAs. [PDF]
PLoS ONE, 2016 Borrelia burgdorferi, the agent of Lyme disease, differentially expresses numerous genes and proteins as it cycles between mammalian hosts and tick vectors.
William K Arnold +5 more
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PLoS Pathogens, 2020 Lyme disease, the most common vector-borne illness in North America, is caused by the spirochete Borrelia burgdorferi. Infection begins in the skin following a tick bite and can spread to the hearts, joints, nervous system, and other organs. Diverse host
Akash Gupta +16 more
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