Results 31 to 40 of about 18,441 (181)

Human neuroglial cells internalize Borrelia burgdorferi by coiling phagocytosis mediated by Daam1. [PDF]

PLoS ONE, 2018
Borrelia burgdorferi, the agent of Lyme borreliosis, can elude hosts' innate and adaptive immunity as part of the course of infection. The ability of B. burgdorferi to invade or be internalized by host cells in vitro has been proposed as a mechanism for ...
Shanna K Williams, Zachary P Weiner, Robert D Gilmore   +2 more
doaj   +1 more source

Epidemiology and molecular genetic characteristics of Lyme borreliosis pathogens circulating in tick’s population in the Almaty oblast of the Republic of Kazakhstan

Журнал микробиологии, эпидемиологии и иммунобиологии, 2021
Background. Information on the geographical distribution of different species of the Borrelia burgdorferi sensu lato (B. burgdorferi s.l.) complex is of great epidemiological importance, since different genospecies are associated with certain clinical ...
A. O. Bissenbay, A. V. Zhigailov, Yu. V. Perfilyeva, D. A. Naizabayeva, A. S. Neupokoyeva, Zh. A. Berdygulova, Ye. O. Ostapchuk, E. R. Maltseva, S. A. Kuatbekova, A. S. Nizkorodova, A. M. Dmitrovskiy, Yu. A. Skiba, S. M. Mamadaliyev   +12 more
doaj   +1 more source

Identification of Borrelia burgdorferi and B. hermsii using DNA hybridization probes [PDF]

Journal of Clinical Microbiology, 1989
Fragments of plasmid DNA from Borrelia burgdorferi and B. hermsii were cloned and tested for specificity as hybridization probes to identify these two species of pathogenic spirochetes. Three fragments from the 49-kilobase-pair linear plasmid of B.
T G, Schwan, W J, Simpson, M E, Schrumpf, R H, Karstens   +3 more
openaire   +2 more sources

Genotypic variation and mixtures of Lyme Borrelia in Ixodes ticks from North America and Europe. [PDF]

PLoS ONE, 2010
Lyme disease, caused by various species of Borrelia, is transmitted by Ixodes ticks in North America and Europe. Studies have shown the genotype of Borrelia burgdorferi sensu stricto (s.s.) or the species of B.
Chris D Crowder, Heather E Matthews, Steven Schutzer, Megan A Rounds, Benjamin J Luft, Oliver Nolte, Scott R Campbell, Curtis A Phillipson, Feng Li, Ranga Sampath, David J Ecker, Mark W Eshoo   +11 more
doaj   +1 more source

Maternal transfer of oral vaccine induced anti-OspA antibodies protects Peromyscus spp. from tick-transmitted Borrelia burgdorferi

Infection and Immunity
The efficacy and duration of passive immunity protection depend on maternal antibody levels and transfer efficiency. We investigated whether oral vaccination of Peromyscus leucopus dams with recombinant outer surface protein A (OspA)-expressing ...
Jose F. Azevedo, Greg Joyner, Suman Kundu, Kamalika Samanta, Maria Gomes-Solecki   +4 more
doaj   +1 more source

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

iNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu, Gayani K. Nanayakkara, Yifan Lu, Fatma Saaoud, Keman Xu, Ying Shao, Bo Yuan, Shih‐Yu Hung, Haiyan Xiang, Xianwei Wang, Sadia Mohsin, Sheng Wu, Xiaolei Liu, Juncheng Wei, Zhengjie Zhou, Beata Kosmider, Mingui Fu, Laisel Martinez, Roberto Vazquez‐Padron, Wenhui Hu, Shuping Ge, Hong Wang, Xiaofeng Yang   +22 more
wiley   +1 more source

Demonstration of Borrelia burgdorferi DNA in urine samples from healthy humans whose sera contain B. burgdorferi-specific antibodies [PDF]

Journal of Clinical Microbiology, 1994
Since the possibility of asymptomatic infection with Borrelia burgdorferi has been suggested by a positive serology found in healthy subjects, we hypothesized that these subjects might excrete borrelial DNA sequences in urine as happens in patients with Lyme borreliosis.
H, Karch, H I, Huppertz, M, Böhme, H, Schmidt, D, Wiebecke, A, Schwarzkopf   +5 more
openaire   +2 more sources

Borrelia and Genital Lichen Sclerosus: A Critical Review of the Evidence

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Lichen sclerosus (LSc) is a chronic inflammatory dermatosis that primarily affects the genitalia. Growing evidence supports chronic occlusive urine exposure as the principal pathogenic driver, though other mechanisms, including mechanical irritation, hormonal influences, autoimmunity, and infection, have been proposed.
Liang Zhi Wong, Richard Watchorn, Sandra Jerkovic Gulin, Christopher B. Bunker, Georgios Kravvas   +4 more
wiley   +1 more source

Effect of Invasion of Borrelia burgdorferi in Normal and Neoplastic Mammary Epithelial Cells

Antibiotics, 2021
Borrelia burgdorferi, the causative agent of Lyme Disease, is known to be able to disseminate and colonize various organs and tissues of its hosts, which is very crucial for its pathogenicity and survival.
Gauri Gaur, Janhavi Y. Sawant, Ankita S. Chavan, Vishwa A. Khatri, Yueh-Hsin Liu, Min Zhang, Eva Sapi   +6 more
doaj   +1 more source

‘Reservoir dogs’: The emerging zoonotic risk associated with European dog imports to the UK

Veterinary Record, EarlyView.
Abstract Background The movement of dogs from continental Europe to the UK poses a growing public health threat due to the associated risk of disease incursions. Current legislation is insufficient to address the risks and pre‐import control measures are focused only on rabies virus and the fox tapeworm Echinococcus multilocularis. Methods We conducted
Poppy Simonson, Tapan Bhattacharyya, Michael A. Miles   +2 more
wiley   +1 more source