Results 31 to 40 of about 18,726 (190)

Local Community Composition Drives Avian Borrelia burgdorferi Infection and Tick Infestation

Veterinary Sciences, 2022
Globally, zoonotic vector-borne diseases are on the rise and understanding their complex transmission cycles is pertinent to mitigating disease risk.
Marie Lilly, Wilmer Amaya-Mejia, Lucas Pavan, Ceili Peng, Arielle Crews, Nghia Tran, Ravinder Sehgal, Andrea Swei   +7 more
doaj   +1 more source

B. burgdorferi enrichment from feeding ticks v1

, 2022
Borrelia burgdorferi (Bb), the causative agent of Lyme disease, must adapt to vastly different environments as the bacterium cycles between the tick vector and a vertebrate host. During a bloodmeal, Bb migrates from the tick midgut to the salivary glands and changes its gene expression, priming Bb for vertebrate infection.
Anne Sapiro, Jenny Zhang, Beth Hayes, Seemay Chou   +3 more
openaire   +1 more source

Genotypic variation and mixtures of Lyme Borrelia in Ixodes ticks from North America and Europe. [PDF]

PLoS ONE, 2010
Lyme disease, caused by various species of Borrelia, is transmitted by Ixodes ticks in North America and Europe. Studies have shown the genotype of Borrelia burgdorferi sensu stricto (s.s.) or the species of B.
Chris D Crowder, Heather E Matthews, Steven Schutzer, Megan A Rounds, Benjamin J Luft, Oliver Nolte, Scott R Campbell, Curtis A Phillipson, Feng Li, Ranga Sampath, David J Ecker, Mark W Eshoo   +11 more
doaj   +1 more source

Maternal transfer of oral vaccine induced anti-OspA antibodies protects Peromyscus spp. from tick-transmitted Borrelia burgdorferi

Infection and Immunity
The efficacy and duration of passive immunity protection depend on maternal antibody levels and transfer efficiency. We investigated whether oral vaccination of Peromyscus leucopus dams with recombinant outer surface protein A (OspA)-expressing ...
Jose F. Azevedo, Greg Joyner, Suman Kundu, Kamalika Samanta, Maria Gomes-Solecki   +4 more
doaj   +1 more source

Rewriting Tumor Immunity With Bacterial Membrane Vesicles: A Versatile and Potent Therapeutic Strategy

Advanced NanoBiomed Research, EarlyView.
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi, Md Mijanur Rahman, Asma Talukder, Urooj Yousaf Virk, Jennifer C. Wilson, Nigel McMillan, Ming Q. Wei   +6 more
wiley   +1 more source

Evidence for B-lymphocyte mitogen activity in Borrelia burgdorferi-infected mice [PDF]

Infection and Immunity, 1992
Borrelia burgdorferi produces a mitogen for murine B lymphocytes which can be measured in vitro by polyclonal stimulation of proliferation and immunoglobulin production (R. Schoenfeld, B. Araneo, Y. Ma, L. Yang, and J. J. Weis, Infect. Immun. 60:455-464, 1992). Sonicated B. burgdorferi cells also stimulated IL-6 production by splenocyte cultures.
L, Yang, Y, Ma, R, Schoenfeld, M, Griffiths, E, Eichwald, B, Araneo, J J, Weis   +6 more
openaire   +2 more sources

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

iNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu, Gayani K. Nanayakkara, Yifan Lu, Fatma Saaoud, Keman Xu, Ying Shao, Bo Yuan, Shih‐Yu Hung, Haiyan Xiang, Xianwei Wang, Sadia Mohsin, Sheng Wu, Xiaolei Liu, Juncheng Wei, Zhengjie Zhou, Beata Kosmider, Mingui Fu, Laisel Martinez, Roberto Vazquez‐Padron, Wenhui Hu, Shuping Ge, Hong Wang, Xiaofeng Yang   +22 more
wiley   +1 more source

Identification of Borrelia burgdorferi and B. hermsii using DNA hybridization probes [PDF]

Journal of Clinical Microbiology, 1989
Fragments of plasmid DNA from Borrelia burgdorferi and B. hermsii were cloned and tested for specificity as hybridization probes to identify these two species of pathogenic spirochetes. Three fragments from the 49-kilobase-pair linear plasmid of B.
T G, Schwan, W J, Simpson, M E, Schrumpf, R H, Karstens   +3 more
openaire   +2 more sources

Effect of Invasion of Borrelia burgdorferi in Normal and Neoplastic Mammary Epithelial Cells

Antibiotics, 2021
Borrelia burgdorferi, the causative agent of Lyme Disease, is known to be able to disseminate and colonize various organs and tissues of its hosts, which is very crucial for its pathogenicity and survival.
Gauri Gaur, Janhavi Y. Sawant, Ankita S. Chavan, Vishwa A. Khatri, Yueh-Hsin Liu, Min Zhang, Eva Sapi   +6 more
doaj   +1 more source

A Comprehensive Study of Bidirectional Interactions Between the Human Microbiome and Blood Malignancies and Hematologic Conditions: Focus on Novel Therapeutic Strategies

Journal of Clinical Laboratory Analysis, EarlyView.
Microbiota‐targeted therapeutic strategies in hematological disorders. aHSCT: Transplanted immune cells from the donor may attack the recipient's tissues, especially when damage to the intestinal epithelium disrupts the gut microbiota, contributing to GVHD. Maintaining a balanced gut microbiota that supports immune regulation helps reduce GVHD risk and
Alireza Molajafari, Hadi Sedigh Ebrahim‐Saraie, Majid Taati Moghadam, Meysam Hasannejad‐Bibalan   +3 more
wiley   +1 more source