Borrelia burgdorferi exposure in coyotes: an indicator of B. burgdorferi levels in urban versus rural environments. [PDF]
PICO question Do wild coyotes in the US that are in an urban habitat compared to a rural habitat have a higher prevalence of Borrelia burgdorferi seroconversion? Clinical bottom line Category of research question Prevalence The number and type of study designs reviewed Two papers, both utilising a cross-sectional study design Strength of ...
Shultz L, Fausak E.
europepmc +4 more sources
Lyme Neuroborreliosis: Mechanisms of B. burgdorferi Infection of the Nervous System. [PDF]
Lyme borreliosis is the most prevalent tick-borne disease in the United States, infecting ~476,000 people annually. Borrelia spp. spirochetal bacteria are the causative agents of Lyme disease in humans and are transmitted by Ixodes spp ticks. Clinical manifestations vary depending on which Borrelia genospecies infects the patient and may be a ...
Ford L, Tufts DM.
europepmc +5 more sources
Culture of Borrelia burgdorferi [PDF]
Marques et al. (2) recently evaluated a new culture medium for the growth of Borrelia burgdorferi from human blood based on a report by Phillips et al. (3). The MPM medium described by Phillips et al. was prepared with Detroit tap water. However, Marques et al.
Richard C. Tilton +2 more
openaire +1 more source
Synthesis of RpoS is dependent on a putative enhancer binding protein Rrp2 in Borrelia burgdorferi. [PDF]
The RpoN-RpoS regulatory pathway plays a central role in governing adaptive changes by B. burgdorferi when the pathogen shuttles between its tick vector and mammalian hosts.
Zhiming Ouyang +2 more
doaj +1 more source
RNA-Seq of Borrelia burgdorferi in Multiple Phases of Growth Reveals Insights into the Dynamics of Gene Expression, Transcriptome Architecture, and Noncoding RNAs. [PDF]
Borrelia burgdorferi, the agent of Lyme disease, differentially expresses numerous genes and proteins as it cycles between mammalian hosts and tick vectors.
William K Arnold +5 more
doaj +1 more source
Lyme disease, the most common vector-borne illness in North America, is caused by the spirochete Borrelia burgdorferi. Infection begins in the skin following a tick bite and can spread to the hearts, joints, nervous system, and other organs. Diverse host
Akash Gupta +16 more
doaj +1 more source
Background: The presence of co-infections induced by tick-borne pathogens in humans is an important epidemiological phenomenon. This issue has attracted growing attention of doctors and people working under conditions of an increased risk of being ...
Małgorzata Tokarska-Rodak +4 more
doaj +1 more source
Contribution of the infection-associated complement regulator-acquiring surface protein 4 (ErpC) to complement resistance of Borrelia burgdorferi [PDF]
Borrelia burgdorferi evades complement-mediated killing by interacting with complement regulators through distinct complement regulator-acquiring surface proteins (CRASPs).
Hallström, Teresia +6 more
core +4 more sources
Increasing of informational content of serological diagnosis of acute Lyme- borreliosis
Aim. To improve the serological diagnosis of erythematous form of Lyme borreliosis by detecting antibodies to the Borrelia burgdorferi sensu lato (B. burgdorferi sensu stricto, B. afzelii and B.
M.I. Shkilna +7 more
doaj +1 more source
Lyme disease, which is caused by infection with Borrelia burgdorferi and related species, can lead to inflammatory pathologies affecting the joints, heart, and nervous systems including the central nervous system (CNS).
Timothy Casselli +5 more
doaj +1 more source

