Monoinfections caused by Borrelia burgdorferi and Borrelia burgdorferi / Anaplasma phagocytophilum co-infections in forestry workers and farmers [PDF]
Medycyna Pracy, 2015 Background: The presence of co-infections induced by tick-borne pathogens in humans is an important epidemiological phenomenon. This issue has attracted growing attention of doctors and people working under conditions of an increased risk of being ...
Małgorzata Tokarska-Rodak +4 more
doaj +3 more sources
A Dual Luciferase Reporter System for B. burgdorferi Measures Transcriptional Activity during Tick-Pathogen Interactions [PDF]
Frontiers in Cellular and Infection Microbiology, 2017 Knowledge of the transcriptional responses of vector-borne pathogens at the vector-pathogen interface is critical for understanding disease transmission.
Philip P. Adams +2 more
doaj +2 more sources
Identifying platelet-derived factors as amplifiers of B. burgdorferi-induced cytokine production. [PDF]
Clin Exp Immunol, 2022 Previous studies have shown that monocytes can be ‘trained’ or tolerized by certain stimuli to respond stronger or weaker to a secondary stimulation. Rewiring of glucose metabolism was found to be important in inducing this phenotype.
Kerstholt M +18 more
europepmc +4 more sources
Rheumatology, 2011 Borelioza z Lyme ma bogatą symptomatologię i w znacznym odsetkuprzypadków może przypominać wczesne stadia układowej chorobytkanki łącznej. Część pacjentów trafia po wizycie u lekarza POZdo reumatologa.
Karolina Miąskiewicz +9 more
doaj +1 more source
Contribution of the infection-associated complement regulator-acquiring surface protein 4 (ErpC) to complement resistance of Borrelia burgdorferi [PDF]
, 2012 Borrelia burgdorferi evades complement-mediated killing by interacting with complement regulators through distinct complement regulator-acquiring surface proteins (CRASPs).
Teresia Hallström +14 more
core +1 more source
PLoS Pathogens, 2021 Lyme disease, which is caused by infection with Borrelia burgdorferi and related species, can lead to inflammatory pathologies affecting the joints, heart, and nervous systems including the central nervous system (CNS).
Timothy Casselli +5 more
doaj +1 more source
Complement factor H-related proteins CFHR2 and CFHR5 represent novel ligands for the infection-associated CRASP proteins of Borrelia burgdorferi [PDF]
, 2010 Background: One virulence property of Borrelia burgdorferi is its resistance to innate immunity, in particular to complement-mediated killing. Serum-resistant B.
Teresia Hallström +34 more
core +2 more sources
Increasing of informational content of serological diagnosis of acute Lyme- borreliosis
Acta Medica Leopoliensia, 2020 Aim. To improve the serological diagnosis of erythematous form of Lyme borreliosis by detecting antibodies to the Borrelia burgdorferi sensu lato (B. burgdorferi sensu stricto, B. afzelii and B.
M.I. Shkilna +7 more
doaj +1 more source
Early production of IL-22 but not IL-17 by peripheral blood mononuclear cells exposed to live Borrelia burgdorferi: the role of monocytes and interleukin-1 [PDF]
, 2010 If insufficiently treated, Lyme borreliosis can evolve into an inflammatory disorder affecting skin, joints, and the CNS. Early innate immunity may determine host responses targeting infection. Thus, we sought to characterize the immediate cytokine storm
Nicole Darsow +40 more
core +1 more source
Antigen-Specific CD4 T Cell and B Cell Responses to Borrelia burgdorferi. [PDF]
, 2023 Long-lived T-dependent B cell responses fail to develop during persistent infection of mice with Borrelia burgdorferi, the causative agent of Lyme disease, raising questions about the induction and/or functionality of anti-B.
Laura S. Hall +17 more
core +1 more source