B. burgdorferi in Switzerland. [PDF]
Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology, 1987 André Aeschlimann +5 more
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Lyme Neuroborreliosis: Mechanisms of B. burgdorferi Infection of the Nervous System. [PDF]
Brain Sci, 2021 Lyme borreliosis is the most prevalent tick-borne disease in the United States, infecting ~476,000 people annually. Borrelia spp. spirochetal bacteria are the causative agents of Lyme disease in humans and are transmitted by Ixodes spp ticks. Clinical manifestations vary depending on which Borrelia genospecies infects the patient and may be a ...
Ford L, Tufts DM.
europepmc +5 more sources
Identification of three species of Borrelia burgdorferi sensu lato (B. burgdorferi sensu stricto, B. garinii, and B. afzelii) among isolates from acrodermatitis chronica atrophicans lesions. [PDF]
Journal of Investigative Dermatology, 1998 In Europe, at least three species of Borrelia are known to be causative agents of Lyme borreliosis: B. burgdorferi sensu stricto, B. garinii, and B. afzelii. Observable differences in the molecular characteristics of the three species have led to speculation that they may also differ in their pathogenic potential and/or tissue tropisms. Several studies
R. Picken +6 more
semanticscholar +3 more sources
Demonstration of Borrelia burgdorferi DNA in urine samples from healthy humans whose sera contain B. burgdorferi-specific antibodies [PDF]
Journal of Clinical Microbiology, 1994 Since the possibility of asymptomatic infection with Borrelia burgdorferi has been suggested by a positive serology found in healthy subjects, we hypothesized that these subjects might excrete borrelial DNA sequences in urine as happens in patients with Lyme borreliosis.
Helge Karch +5 more
semanticscholar +3 more sources
Identifying platelet-derived factors as amplifiers of B. burgdorferi-induced cytokine production. [PDF]
Clin Exp Immunol, 2022 AbstractPrevious studies have shown that monocytes can be ‘trained’ or tolerized by certain stimuli to respond stronger or weaker to a secondary stimulation. Rewiring of glucose metabolism was found to be important in inducing this phenotype. As we previously found that Borrelia burgdorferi (B. burgdorferi), the causative agent of Lyme borreliosis (LB),
Kerstholt M +18 more
europepmc +5 more sources
Tick-Tattoo: DNA Vaccination Against B. burgdorferi or Ixodes scapularis Tick Proteins. [PDF]
Front Immunol, 2021 IntroductionBorrelia burgdorferi sensu lato (sl) is the causative agent of Lyme borreliosis. Currently there is no human vaccine against Lyme borreliosis, and most research focuses on recombinant protein vaccines. DNA tattoo vaccination with B. afzelii strain PKo OspC in mice has proven to be fully protective against B.
Klouwens MJ +5 more
europepmc +6 more sources
Journal of Clinical Microbiology, 1996 A total of 36 European Borrelia burgdorferi sensu lato cerebrospinal fluid isolates (mainly from southern Germany) were analyzed by pulsed-field gel electrophoresis (PFGE) for large restriction fragment pattern (LRFP) and linear plasmid profiles. Analyzing this large panel of isolates, we detected all three species of B.
Ulrich Busch +6 more
semanticscholar +3 more sources
Decreased Electroporation Efficiency in Borrelia burgdorferi Containing Linear Plasmids lp25 and lp56: Impact on Transformation of Infectious B. burgdorferi [PDF]
Infection and Immunity, 2002 ABSTRACT The presence of the linear plasmids lp25 and lp56 of Borrelia burgdorferi B31 was found to dramatically decrease the rate of transformation by electroporation with the shuttle vector pBSV2, an autonomously replicating plasmid that confers kanamycin resistance (P. E. Stewart, R. Thalken, J. L. Bono,
M. Lawrenz +3 more
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Culture of Borrelia burgdorferi [PDF]
Journal of Clinical Microbiology, 2001 Marques et al. (2) recently evaluated a new culture medium for the growth of Borrelia burgdorferi from human blood based on a report by Phillips et al. (3). The MPM medium described by Phillips et al. was prepared with Detroit tap water. However, Marques et al.
Richard C. Tilton +2 more
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Effect of Borrelia burgdorferi Outer Membrane Vesicles on Host Oxidative Stress Response
Antibiotics, 2020 Outer membrane vesicles (OMVs) are spherical bodies containing proteins and nucleic acids that are released by Gram-negative bacteria, including Borrelia burgdorferi, the causative agent of Lyme disease. The functional relationship between B. burgdorferi
Keith Wawrzeniak +3 more
doaj +1 more source