Results 21 to 30 of about 12,436,409 (236)

Synthesis of RpoS is dependent on a putative enhancer binding protein Rrp2 in Borrelia burgdorferi. [PDF]

open access: yesPLoS ONE, 2014
The RpoN-RpoS regulatory pathway plays a central role in governing adaptive changes by B. burgdorferi when the pathogen shuttles between its tick vector and mammalian hosts.
Zhiming Ouyang   +2 more
doaj   +1 more source

The BosR Is Back! [PDF]

open access: yesMol Microbiol
ABSTRACT BosR is a novel nucleic acid‐binding protein in the ferric uptake regulator (FUR) family that regulates gene expression in the Lyme disease spirochete Borrelia (Borreliella) burgdorferi. This issue of Molecular Microbiology contains a comprehensive transcriptomic study that keenly defines the regulatory swath of BosR in the vertebrate host of ...
Samuels DS, Lybecker MC.
europepmc   +2 more sources

The urokinase receptor (uPAR) facilitates clearance of Borrelia burgdorferi. [PDF]

open access: yesPLoS Pathogens, 2009
The causative agent of Lyme borreliosis, the spirochete Borrelia burgdorferi, has been shown to induce expression of the urokinase receptor (uPAR); however, the role of uPAR in the immune response against Borrelia has never been investigated.
Joppe W R Hovius   +15 more
doaj   +1 more source

Borrelia burgdorferi exposure in coyotes: an indicator of B. burgdorferi levels in urban versus rural environments

open access: yesVeterinary Evidence, 2022
PICO question Do wild coyotes in the US that are in an urban habitat compared to a rural habitat have a higher prevalence of Borrelia burgdorferi seroconversion?   Clinical bottom line Category of research question Prevalence The number and type of study designs reviewed Two papers, both utilising a cross-sectional study design Strength of ...
Laura Shultz, Erik Fausak
openaire   +3 more sources

A murine model of Lyme disease demonstrates that Borrelia burgdorferi colonizes the dura mater and induces inflammation in the central nervous system.

open access: yesPLoS Pathogens, 2021
Lyme disease, which is caused by infection with Borrelia burgdorferi and related species, can lead to inflammatory pathologies affecting the joints, heart, and nervous systems including the central nervous system (CNS).
Timothy Casselli   +5 more
doaj   +1 more source

Monoinfections caused by Borrelia burgdorferi and Borrelia burgdorferi / Anaplasma phagocytophilum co-infections in forestry workers and farmers

open access: yesMedycyna Pracy, 2015
Background: The presence of co-infections induced by tick-borne pathogens in humans is an important epidemiological phenomenon. This issue has attracted growing attention of doctors and people working under conditions of an increased risk of being ...
Małgorzata Tokarska-Rodak   +4 more
doaj   +1 more source

A human secretome library screen reveals a role for Peptidoglycan Recognition Protein 1 in Lyme borreliosis.

open access: yesPLoS Pathogens, 2020
Lyme disease, the most common vector-borne illness in North America, is caused by the spirochete Borrelia burgdorferi. Infection begins in the skin following a tick bite and can spread to the hearts, joints, nervous system, and other organs. Diverse host
Akash Gupta   +16 more
doaj   +1 more source

B. burgdorferi enrichment from feeding ticks v1

open access: yes, 2022
Borrelia burgdorferi (Bb), the causative agent of Lyme disease, must adapt to vastly different environments as the bacterium cycles between the tick vector and a vertebrate host. During a bloodmeal, Bb migrates from the tick midgut to the salivary glands and changes its gene expression, priming Bb for vertebrate infection.
Anne Sapiro   +3 more
openaire   +1 more source

Increasing of informational content of serological diagnosis of acute Lyme- borreliosis

open access: yesActa Medica Leopoliensia, 2020
Aim. To improve the serological diagnosis of erythematous form of Lyme borreliosis by detecting antibodies to the Borrelia burgdorferi sensu lato (B. burgdorferi sensu stricto, B. afzelii and B.
M.I. Shkilna   +7 more
doaj   +1 more source

Increased Borrelia burgdorferi Seroprevalence in Nova Scotia-Prevalence and Distribution 10 Years Later. [PDF]

open access: yesZoonoses Public Health
ABSTRACT Lyme disease (LD), a tick‐borne infection, is endemic in Nova Scotia. One decade ago, the seropositivity rate to Borrelia burgdorferi was 2/1855 (0.14%). In the current study, using residual sera representing ages 10–64 years, we demonstrate an increase in seroprevalence, to 25/1872 (1.60%), with the highest seroprevalence in the western area ...
Phillips C   +10 more
europepmc   +2 more sources

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