Contribution of the infection-associated complement regulator-acquiring surface protein 4 (ErpC) to complement resistance of Borrelia burgdorferi [PDF]
, 2012 Borrelia burgdorferi evades complement-mediated killing by interacting with complement regulators through distinct complement regulator-acquiring surface proteins (CRASPs).
Hammerschmidt, Claudia +6 more
core +3 more sources
B. burgdorferi enrichment from feeding ticks v1
, 2022 Borrelia burgdorferi (Bb), the causative agent of Lyme disease, must adapt to vastly different environments as the bacterium cycles between the tick vector and a vertebrate host. During a bloodmeal, Bb migrates from the tick midgut to the salivary glands and changes its gene expression, priming Bb for vertebrate infection.
Anne Sapiro +3 more
openaire +1 more source
Increasing of informational content of serological diagnosis of acute Lyme- borreliosis
Acta Medica Leopoliensia, 2020 Aim. To improve the serological diagnosis of erythematous form of Lyme borreliosis by detecting antibodies to the Borrelia burgdorferi sensu lato (B. burgdorferi sensu stricto, B. afzelii and B.
M.I. Shkilna +7 more
doaj +1 more source
Demonstration of Borrelia burgdorferi DNA in urine samples from healthy humans whose sera contain B. burgdorferi-specific antibodies [PDF]
Journal of Clinical Microbiology, 1994 Since the possibility of asymptomatic infection with Borrelia burgdorferi has been suggested by a positive serology found in healthy subjects, we hypothesized that these subjects might excrete borrelial DNA sequences in urine as happens in patients with Lyme borreliosis.
H, Karch +5 more
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Identification of New Drug Candidates Against \u3cem\u3eBorrelia burgdorferi\u3c/em\u3e Using High-Throughput Screening [PDF]
, 2016 Lyme disease is the most common zoonotic bacterial disease in North America. It is estimated that .300,000 cases per annum are reported in USA alone. A total of 10%–20% of patients who have been treated with antibiotic therapy report the recrudescence of
Babar, Mustafeez Mujtaba +9 more
core +3 more sources
Clinical and Developmental Immunology, 2012 Borrelia burgdorferi is a spirochetal bacterium that causes Lyme disease. These studies address whether current research methods using either ELISA to detect seroconversion to B.
John J. Lazarus +3 more
doaj +1 more source
Annals of Agricultural and Environmental Medicine, 2019 Introduction Ticks (Acari: Ixodida) are vectors and/or reservoirs of many pathogens, i.e. Borrelia burgdorferi sensu lato, Anaplasma phagocytophilum and Babesia microti .
Marek Asman +4 more
doaj +1 more source
Landscape structure affects the prevalence and distribution of a tick-borne zoonotic pathogen [PDF]
, 2018 Background Landscape structure can affect pathogen prevalence and persistence with consequences for human and animal health. Few studies have examined how reservoir host species traits may interact with landscape structure to alter pathogen communities ...
A Mannelli +66 more
core +5 more sources
Eco-epidemiology of Borrelia miyamotoi and Lyme borreliosis spirochetes in a popular hunting and recreational forest area in Hungary [PDF]
, 2015 BACKGROUND: Borrelia miyamotoi, the newly discovered human pathogenic relapsing fever spirochete, and Borrelia burgdorferi sensu lato are maintained in natural rodent populations. The aim of this study was to investigate the natural cycle of B. miyamotoi
Coipan, Elena Claudia +6 more
core +1 more source
Evidence for B-lymphocyte mitogen activity in Borrelia burgdorferi-infected mice [PDF]
Infection and Immunity, 1992 Borrelia burgdorferi produces a mitogen for murine B lymphocytes which can be measured in vitro by polyclonal stimulation of proliferation and immunoglobulin production (R. Schoenfeld, B. Araneo, Y. Ma, L. Yang, and J. J. Weis, Infect. Immun. 60:455-464, 1992). Sonicated B. burgdorferi cells also stimulated IL-6 production by splenocyte cultures.
L, Yang +6 more
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