Results 91 to 100 of about 1,188,690 (195)
Furin‐Mediated Cleavage of Zona Pellucida Proteins Is Essential for Oocyte Development
MedComm, Volume 6, Issue 12, December 2025.The furin cleavage site mutation leads to a failure in transmembrane transport process of non‐modified ZP2 protein. This unsuccessful ZP2 secretion might result in the decreased expression of exocytosis complex SNAREs, which further induces oocyte apoptosis via p53 pathway and PI3K signaling.
Tiechao Ruan +15 more
wiley +1 more source
, 2015 Expression of target miRNA seed sequences (A) miR-690 and (B) miR-223 determined to be important in radiation combined skin burn injury pathways of female B6D2F1/J mice subjected to skin burn injury alone (BURN), whole-body ionizing irradiation alone (RI)
Joshua M. Swift (628430) +3 more
core +1 more source
Innate NKTγδ and NKTαβ cells exert similar functions and compete for a thymic niche.
, 2012 International audienceThe transcriptional regulator promyelocytic leukemia zinc finger (PLZF) is highly expressed during the differentiation of natural killer T (NKT) cells and is essential for the acquisition of their effector/memory innate-like ...
Laurent Boucontet +3 more
core +1 more source
, 2013 Para pesquisa experimental relacionada à síndrome metabólica (SM) e diabetes melito tipo 2 (DMT2), uma dieta que induz obesidade e que desenvolve alterações em modelos animais não alterados geneticamente, é essencial.
Nolli, Adriane Paduan [UNESP]
core +2 more sources
IL-5, MCP-1, G-CSF and KC cytokine levels in serum of sham, burn, RI and CI mice.
, 2015 Analysis performed using cytokine multiplex assays to assess (A) IL-5, (B) MCP-1, (C) G-CSF and (D) KC serum levels in female B6D2F1/J mice subjected to skin burn injury alone (BURN), whole-body ionizing irradiation alone (RI) or when combined with skin ...
Joshua M. Swift (628430) +3 more
core +1 more source
Frontiers in Neuroscience, 2018 Background: Accumulation of the α-synuclein (α-syn) protein and depletion of dopaminergic neurons in the substantia nigra are hallmarks of Parkinson’s disease (PD).
Jared Schommer +3 more
doaj +1 more source
Strain differences in the radiosensitivity of mouse spermatogonia
, 1985 The radiosensitivity of spermatogonia was found to be greater by up to a factor of 2 in C3H mice than in B6D2F1 mice, whether assessed for the highly sensitive spermatogonia (types A2 to In) or the much more resistant clonogenic spermatogonia which ...
Bianchi, M +3 more
core +1 more source
Fullerol treatment reduces mortality and clinical signs in experimental GVHD.
, 2015 GVHD was induced by the transfer of 3 x 107 splenocytes from C57BL/6J donors to B6D2F1 mice that were irradiated with low dose two days before transplantation.
Maurício V. B. Pinheiro (721078) +11 more
core +1 more source
Abnormal gene expression in regular and aggregated somatic cell nuclear transfer placentas
BMC Biotechnology, 2017 Background Placental defects in somatic cell nuclear transfer (SCNT) are a major cause of complications during pregnancy. One of the most critical factors for the success of SCNT is the successful epigenetic reprogramming of donor cells. Recently, it was
Bo-Woong Sim +3 more
doaj +1 more source
Macrophage Activation by Adjuvants in Aging Mice
, 1984 Peritoneal macrophages from young (3–8 mo) and aging (12–29 mo) mice of the C58, BALB/c, C3H/He, C57BI/6J, and B6D2F1 strains were compared for their capacity to become activated by various adjuvants in four assays.
Arthur G Johnson, Pamela R Petrequin
core +1 more source