Results 1 to 10 of about 911 (209)

Beyond the Inner Cell Mass: Evaluating the Impact of Inner Cell Mass Visibility on Implantation Prediction in Static Blastocyst Images – A Retrospective Cohort Study

Journal of Human Reproductive Sciences
Background: Embryo selection in IVF often relies on inner cell mass (ICM) morphology as a predictor of implantation. However, in static two-dimensional images, ICM visibility may be limited by technical factors like orientation or focus, rather than ...
Gaurav Majumdar
doaj   +7 more sources

Entropy sorting of single-cell RNA sequencing data reveals the inner cell mass in the human pre-implantation embryo

Stem Cell Reports, 2023
Summary: A major challenge in single-cell gene expression analysis is to discern meaningful cellular heterogeneity from technical or biological noise. To address this challenge, we present entropy sorting (ES), a mathematical framework that distinguishes
Arthur Radley, Elena Corujo-Simon, Jennifer Nichols, Austin Smith, Sara-Jane Dunn   +4 more
doaj   +3 more sources

Nr5a2 ensures inner cell mass formation in mouse blastocyst

Cell Reports
Summary: Recent studies have elucidated Nr5a2’s role in activating zygotic genes during early mouse embryonic development. Subsequent research, however, reveals that Nr5a2 is not critical for zygotic genome activation but is vital for the gene program ...
Yanhua Zhao, Meiting Zhang, Jiqiang Liu, Xinglin Hu, Yuchen Sun, Xingwei Huang, Jingyu Li, Lei Lei   +7 more
doaj   +3 more sources

Beyond the Inner Cell Mass: Evaluating the Impact of Inner Cell Mass Visibility on Implantation Prediction in Static Blastocyst Images

Journal of Human Reproductive Sciences
Doel Bose Pande, Hemant Deshmukh, Sandeep Kumar Verma, Gajendra Singh Tomar   +3 more
doaj   +4 more sources

A Haspin promoter element induces tissue-specific methylation of a transcription region and the regulation of gene expression in mouse ova [PDF]

Cell Journal, 2022
HASPIN is a nuclear serine-threonine kinase originally identified in the mouse testis. Its 193 bp DNA promoter element(hereafter, 193PE) regulates bidirectional, synchronous gene expression in the germ cells of male mice.
Hiromitsu Tanaka, Keizo Tokuhiro
doaj   +1 more source

Morphology of inner cell mass: a better predictive biomarker of blastocyst viability [PDF]

PeerJ, 2022
Background Transfer of embryos at the blastocyst stage is one of the best approaches for achieving a higher success rate in In vitro fertilization (IVF) treatment as it demonstrates an improved uterine and embryonic synchrony at implantation.
Sargunadevi Sivanantham, Mahalakshmi Saravanan, Nidhi Sharma, Jayashree Shrinivasan, Ramesh Raja   +4 more
doaj   +2 more sources

Mosaicism in the inner cell mass of human blastocysts [PDF]

Human Reproduction, 1998
Although mosaicism was shown to be a normal feature in cleaving embryos, its consequences for the late preimplantation stages are unknown. We performed blastocyst immunosurgery, followed by fluorescent in-situ hybridization (FISH), to determine the number of cells and degree of mosaicism in the inner cell mass (ICM) of human blastocysts.
S, Evsikov, Y, Verlinsky
openaire   +2 more sources

Glutamine transport by mouse inner cell masses [PDF]

Reproduction, 1995
Abstract Mouse blastocysts take up glutamine by specific transport systems. Glutamine is an important precursor for macromolecular synthesis and a potential alternative fuel to glucose. This study compared glutamine uptake in blastocysts and isolated inner cell masses and characterized the major participating systems in the latter ...
Jamshidi M.B., Kaye P.L.
openaire   +4 more sources

Ploidy Testing of Blastocoel Fluid for Screening May Be Technically Challenging and More Invasive Than That of Spent Cell Culture Media

Frontiers in Physiology, 2022
BackgroundRecent studies have demonstrated that both blastocoel fluid (BF) and spent cell culture media (SCM) have potential as materials for non-invasive or less-invasive pre-implantation genetic analysis.
Wenhao Shi, Zhenghao Zhao, Xia Xue, Qian Li, Yaxin Yao, Dongyang Wang, Jing Wang, Sijia Lu, Juanzi Shi   +8 more
doaj   +1 more source

A Shorter Equilibration Period Improves Post-Warming Outcomes after Vitrification and in Straw Dilution of In Vitro-Produced Bovine Embryos

Biology, 2021
This study was designed to the optimize vitrification and in-straw warming protocol of in vitro-produced bovine embryos by comparing two different equilibration periods, short equilibrium (SE: 3 min) and long equilibrium (LE: 12 min).
Iris Martínez-Rodero, Tania García-Martínez, Erika Alina Ordóñez-León, Meritxell Vendrell-Flotats, Carlos Olegario Hidalgo, Joseba Esmoris, Xabier Mendibil, Sabino Azcarate, Manel López-Béjar, Marc Yeste, Teresa Mogas   +10 more
doaj   +1 more source