Results 11 to 20 of about 911 (209)
BackgroundThe scoring system for human blastocysts is traditionally based on morphology; however, there are controversies on the effect of morphology parameters on pregnancy outcomes.
Jihui Ai +5 more
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Characterizing Inner Pressure and Stiffness of Trophoblast and Inner Cell Mass of Blastocysts [PDF]
It has long been recognized that mechanical forces underlie mammalian embryonic shape changes. Before gastrulation, the blastocyst embryo undergoes significant shape changes, namely, the blastocyst cavity emerges and expands, and the inner cell mass (ICM) forms and changes in shape.
Xian, Wang +5 more
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Cell fate clusters in ICM organoids arise from cell fate heredity and division: a modelling approach
During the mammalian preimplantation phase, cells undergo two subsequent cell fate decisions. During the first decision, the trophectoderm and the inner cell mass are formed.
Tim Liebisch +5 more
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Replacement of inner cell mass in mouse
The intraor inter-strain reconstituted blastocysts were produced by replacing the inner cell mass of Kunming mouse blastocysts with that of Kunming or C57BL/6 mouse strain blastocysts. A total of 192 intra-strain reconstituted blastocysts were transferred into 17 pseudo-pregnant Kunming mice, and 2 reconstituted embryos were developed into term; while ...
Chunming Bi +4 more
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Role of the inner cell mass in controlling implantation in the mouse [PDF]
Summary. Studies with mouse blastocysts and trophoblastic vesicles showed that the inner cell mass was not essential for controlling trophoblast activity during delay of implantation.
M H, Snow, J, Aitken, J D, Ansell
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Generating porcine chimeras using inner cell mass cells and parthenogenetic preimplantation embryos. [PDF]
BACKGROUND: The development and validation of stem cell therapies using induced pluripotent stem (iPS) cells can be optimized through translational research using pigs as large animal models, because pigs have the closest characteristics to humans among ...
Kazuaki Nakano +16 more
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BackgroundElective single blastocyst transfer (eSBT) is considered to reduce the incidence of multiple pregnancy compared to double embryo transfer. Blastocyst selection is the key to achieving pregnancy.
Bing-Xin Ma +4 more
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Moving Inward: Establishing the Mammalian Inner Cell Mass [PDF]
Early in mammalian development, a few cells move to the center of the embryo to establish the inner cell mass-the early precursor of the fetus. In this issue of Developmental Cell, Samarage et al. (2015) shed light on how these cells move inward.
Goldstein, Bob, Kiehart, Daniel P.
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The segregation of the trophectoderm (TE) from the inner cell mass (ICM) in the mouse blastocyst is determined by position-dependent Hippo signaling. However, the window of responsiveness to Hippo signaling, the exact timing of lineage commitment and the
Eszter Posfai +7 more
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A developmental insurance policy
Why does a totipotent state linger within the inner cell mass of mouse embryos?
Nestor Saiz, Anna-Katerina Hadjantonakis
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