Results 11 to 20 of about 911 (209)

The Morphology of Inner Cell Mass Is the Strongest Predictor of Live Birth After a Frozen-Thawed Single Embryo Transfer

open access: yesFrontiers in Endocrinology, 2021
BackgroundThe scoring system for human blastocysts is traditionally based on morphology; however, there are controversies on the effect of morphology parameters on pregnancy outcomes.
Jihui Ai   +5 more
doaj   +1 more source

Characterizing Inner Pressure and Stiffness of Trophoblast and Inner Cell Mass of Blastocysts [PDF]

open access: yesBiophysical Journal, 2018
It has long been recognized that mechanical forces underlie mammalian embryonic shape changes. Before gastrulation, the blastocyst embryo undergoes significant shape changes, namely, the blastocyst cavity emerges and expands, and the inner cell mass (ICM) forms and changes in shape.
Xian, Wang   +5 more
openaire   +2 more sources

Cell fate clusters in ICM organoids arise from cell fate heredity and division: a modelling approach

open access: yesScientific Reports, 2020
During the mammalian preimplantation phase, cells undergo two subsequent cell fate decisions. During the first decision, the trophectoderm and the inner cell mass are formed.
Tim Liebisch   +5 more
doaj   +1 more source

Replacement of inner cell mass in mouse

open access: yesChinese Science Bulletin, 2003
The intraor inter-strain reconstituted blastocysts were produced by replacing the inner cell mass of Kunming mouse blastocysts with that of Kunming or C57BL/6 mouse strain blastocysts. A total of 192 intra-strain reconstituted blastocysts were transferred into 17 pseudo-pregnant Kunming mice, and 2 reconstituted embryos were developed into term; while ...
Chunming Bi   +4 more
openaire   +2 more sources

Role of the inner cell mass in controlling implantation in the mouse [PDF]

open access: yesReproduction, 1976
Summary. Studies with mouse blastocysts and trophoblastic vesicles showed that the inner cell mass was not essential for controlling trophoblast activity during delay of implantation.
M H, Snow, J, Aitken, J D, Ansell
openaire   +2 more sources

Generating porcine chimeras using inner cell mass cells and parthenogenetic preimplantation embryos. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: The development and validation of stem cell therapies using induced pluripotent stem (iPS) cells can be optimized through translational research using pigs as large animal models, because pigs have the closest characteristics to humans among ...
Kazuaki Nakano   +16 more
doaj   +1 more source

Cytoplasmic strings between ICM and mTE are a positive predictor of clinical pregnancy and live birth outcomes: A time-lapse study

open access: yesFrontiers in Medicine, 2022
BackgroundElective single blastocyst transfer (eSBT) is considered to reduce the incidence of multiple pregnancy compared to double embryo transfer. Blastocyst selection is the key to achieving pregnancy.
Bing-Xin Ma   +4 more
doaj   +1 more source

Moving Inward: Establishing the Mammalian Inner Cell Mass [PDF]

open access: yesDevelopmental Cell, 2015
Early in mammalian development, a few cells move to the center of the embryo to establish the inner cell mass-the early precursor of the fetus. In this issue of Developmental Cell, Samarage et al. (2015) shed light on how these cells move inward.
Goldstein, Bob, Kiehart, Daniel P.
openaire   +2 more sources

Position- and Hippo signaling-dependent plasticity during lineage segregation in the early mouse embryo

open access: yeseLife, 2017
The segregation of the trophectoderm (TE) from the inner cell mass (ICM) in the mouse blastocyst is determined by position-dependent Hippo signaling. However, the window of responsiveness to Hippo signaling, the exact timing of lineage commitment and the
Eszter Posfai   +7 more
doaj   +1 more source

A developmental insurance policy

open access: yeseLife, 2017
Why does a totipotent state linger within the inner cell mass of mouse embryos?
Nestor Saiz, Anna-Katerina Hadjantonakis
doaj   +1 more source

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