Results 21 to 30 of about 927 (206)

Moving Inward: Establishing the Mammalian Inner Cell Mass [PDF]

Developmental Cell, 2015
Early in mammalian development, a few cells move to the center of the embryo to establish the inner cell mass-the early precursor of the fetus. In this issue of Developmental Cell, Samarage et al. (2015) shed light on how these cells move inward.
Goldstein, Bob, Kiehart, Daniel P.
openaire   +2 more sources

Position- and Hippo signaling-dependent plasticity during lineage segregation in the early mouse embryo

eLife, 2017
The segregation of the trophectoderm (TE) from the inner cell mass (ICM) in the mouse blastocyst is determined by position-dependent Hippo signaling. However, the window of responsiveness to Hippo signaling, the exact timing of lineage commitment and the
Eszter Posfai, Sophie Petropoulos, Flavia Regina Oliveira de Barros, John Paul Schell, Igor Jurisica, Rickard Sandberg, Fredrik Lanner, Janet Rossant   +7 more
doaj   +1 more source

Cytoplasmic strings between ICM and mTE are a positive predictor of clinical pregnancy and live birth outcomes: A time-lapse study

Frontiers in Medicine, 2022
BackgroundElective single blastocyst transfer (eSBT) is considered to reduce the incidence of multiple pregnancy compared to double embryo transfer. Blastocyst selection is the key to achieving pregnancy.
Bing-Xin Ma, Liu Yang, Yu Tian, Lei Jin, Bo Huang   +4 more
doaj   +1 more source

A developmental insurance policy

eLife, 2017
Why does a totipotent state linger within the inner cell mass of mouse embryos?
Nestor Saiz, Anna-Katerina Hadjantonakis
doaj   +1 more source

Effect of follicular fluid supplementation during in vitro maturation on total cell number in bovine blastocysts produced in vitro

Revista Brasileira de Zootecnia, 2014
This study evaluated the influence of follicular fluid (FF) added to the maturation medium on the quality of bovine embryos produced in vitro. In the first experiment, oocytes were matured in media containing five different FF concentrations with ...
Maria Helena Coelho Cruz, Naiara Zoccal Saraiva, Jurandir Ferreira da Cruz, Clara Slade Oliveira, Maite Del Collado, Hugo Fernandes, Fernanda Cavallari de Castro, Joaquim Mansano Garcia   +7 more
doaj   +3 more sources

Transcriptomic profiling of porcine pluripotency identifies species-specific reprogramming requirements for culturing iPSCs

Stem Cell Research, 2019
Porcine embryonic and induced pluripotent stem cells (ESCs; iPSCs) have proven difficult to derive and maintain in vitro. This may be due to inappropriate culturing conditions and incomplete activation of proper pluripotency networks.
Mette Habekost, Arne Lund Jørgensen, Per Qvist, Mark Denham   +3 more
doaj   +1 more source

The salt-and-pepper pattern in mouse blastocysts is compatible with signaling beyond the nearest neighbors

iScience, 2023
Summary: Embryos develop in a concerted sequence of spatiotemporal arrangements of cells. In the preimplantation mouse embryo, the distribution of the cells in the inner cell mass evolves from a salt-and-pepper pattern to spatial segregation of two ...
Sabine C. Fischer, Simon Schardt, Joaquín Lilao-Garzón, Silvia Muñoz-Descalzo   +3 more
doaj   +1 more source

Leukemia Inhibitory Factor Stimulates Primitive Endoderm Expansion in the Bovine Inner Cell Mass

Frontiers in Animal Science, 2021
Previous work determined that bovine interleukin-6 (IL6) increases inner cell mass (ICM), primitive endoderm (PE), and total cell number in in vitro produced (IVP) bovine blastocysts.
Lydia K. Wooldridge, Alan D. Ealy
doaj   +1 more source

Bovine conceptus of Bos indicus produced by somatic cell nuclear transfer and parthenogenesis present morphological variations since the blastocyst stage

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2015
In cattle, embryo development is characterized by the appearance of two distinct cell layers, the trophectoderm and the inner cell mass. The latter will undergo differentiation to form the embryonic disc consisting of the epiblast and hypoblast.
F.D. Oliveira, J.R. Sangalli, F.V. Meirelles, F. Perecin, P.P.C. Silva Filho, Y.F. Watanabe, M.A. Miglino, A.C. Assis Neto   +7 more
doaj   +1 more source

The location of "8"-shaped hatching influences inner cell mass formation in mouse blastocysts. [PDF]

PLoS ONE, 2017
The hatching of a blastocyst where the blastocyst portions on the inside and the outside of the zona pellucida feature a figure-of-eight shape is termed "8"-shaped hatching; this type of hatching has been reported to affect the proper presentation of the
Yohei Onodera, Kazumasa Takahashi, Mayumi Goto, Mibuki Anzai, Natsuki Ono, Hiromitsu Shirasawa, Wataru Sato, Hiroshi Miura, Naoki Sato, Akira Sato, Yukiyo Kumazawa, Yukihiro Terada   +11 more
doaj   +1 more source