Results 31 to 40 of about 911 (209)
Establishment of trophectoderm and inner cell mass lineages in the mouse embryo [PDF]
Molecular Reproduction and Development, 2009 AbstractThe first cell lineage specification in mouse embryo development is the formation of trophectoderm (TE) and inner cell mass (ICM) of the blastocyst. This article is to review and discuss the current knowledge on the cellular and molecular mechanisms of this particular event.
Yusuke, Marikawa, Vernadeth B, Alarcón
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Completely ES cell-derived mice produced by tetraploid complementation using inner cell mass (ICM) deficient blastocysts. [PDF]
PLoS ONE, 2014 Tetraploid complementation is often used to produce mice from embryonic stem cells (ESCs) by injection of diploid (2n) ESCs into tetraploid (4n) blastocysts (ESC-derived mice). This method has also been adapted to mouse cloning and the derivation of mice
Duancheng Wen +4 more
doaj +1 more source
Morphometric assessment of blastocysts: relationship with the ongoing pregnancy rate
F&S Reports, 2023 Objective: To explore a morphometric grading system for blastocysts that is associated with ongoing pregnancy. Design: Cross-sectional study. Setting: None.
Hiroki Utsuno, Ph.D. +9 more
doaj +1 more source
SNAI1 and SNAI2 are asymmetrically expressed at the 2-cell stage and become segregated to the TE in the mouse blastocyst. [PDF]
PLoS ONE, 2009 SNAI1 and SNAI2 are transcription factors that initiate Epithelial-to-Mesenchymal cell transitions throughout development and in cancer metastasis. Here we show novel expression of SNAI1 and SNAI2 throughout mouse preimplantation development revealing ...
Christine E Bell, Andrew J Watson
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Gynecological Endocrinology, 2023 Research question To determine whether blastocyst quality affects the sex ratio at birth through a single blastocyst frozen - thawed embryo transfer (SBFET) cycle.Design In this retrospective analysis, we examined 3,041 singleton infants born following ...
Yuling Mao +6 more
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Glucose metabolism in the trophectoderm and inner cell mass of the rabbit embryo [PDF]
Reproduction, 1991 Summary. The metabolism of glucose in the intact Day-6 and -7 post coitum (p.c.) rabbit blastocyst and in the separated trophectoderm and inner cell mass (ICM) of the Day-7 p.c. embryo was investigated. At Day-6 p.c., glucose traversed the trophectoderm with a half-time of 39 ± 9·3 min, and was metabolized to CO2 at a rate of 25·5 ± 1·6 nmol·cm−2·h−1 ...
D H, Robinson, D J, Benos
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
浙江大学学报. 农业与生命科学版, 2023 Low reproductive efficiency of high-yielding dairy cows is a worldwide challenge, among which the high mortality rate of early embryos is one of the main reasons.
WU Xiaotong +4 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source