Results 31 to 40 of about 9,113,445 (285)

Moving Inward: Establishing the Mammalian Inner Cell Mass. [PDF]

Dev Cell, 2015
Early in mammalian development, a few cells move to the center of the embryo to establish the inner cell mass-the early precursor of the fetus. In this issue of Developmental Cell, Samarage et al. (2015) shed light on how these cells move inward.
Goldstein B, Kiehart DP.
europepmc   +4 more sources

Numb is not a critical regulator of Notch-mediated cell fate decisions in the developing chick inner ear. [PDF]

, 2015
The Notch signaling pathway controls differentiation of hair cells and supporting cells in the vertebrate inner ear. Here, we have investigated whether Numb, a known regulator of Notch activity in Drosophila, is involved in this process in the embryonic ...
Mark eEddison, Weber, SJ, Ariza-McNaughton, L, Julian eLewis, Nicolas eDaudet, Lewis, J, Sara Johanna Weber, Eddison, M, Daudet, N, Linda eAriza-McNaughton, Sara J. Weber, Mark Eddison, Linda Ariza-McNaughton, Julian Lewis, Nicolas Daudet   +14 more
core   +1 more source

Cytoplasmic strings between ICM and mTE are a positive predictor of clinical pregnancy and live birth outcomes: A time-lapse study

Frontiers in Medicine, 2022
BackgroundElective single blastocyst transfer (eSBT) is considered to reduce the incidence of multiple pregnancy compared to double embryo transfer. Blastocyst selection is the key to achieving pregnancy.
Bing-Xin Ma, Liu Yang, Yu Tian, Lei Jin, Bo Huang   +4 more
doaj   +1 more source

Generating porcine chimeras using inner cell mass cells and parthenogenetic preimplantation embryos. [PDF]

PLoS ONE, 2013
BACKGROUND: The development and validation of stem cell therapies using induced pluripotent stem (iPS) cells can be optimized through translational research using pigs as large animal models, because pigs have the closest characteristics to humans among ...
Kazuaki Nakano, Masahito Watanabe, Hitomi Matsunari, Taisuke Matsuda, Kasumi Honda, Miki Maehara, Takahiro Kanai, Gota Hayashida, Mirina Kobayashi, Momoko Kuramoto, Yoshikazu Arai, Kazuhiro Umeyama, Shuh-Hei Fujishiro, Yoshihisa Mizukami, Masaki Nagaya, Yutaka Hanazono, Hiroshi Nagashima   +16 more
doaj   +1 more source

Role of the inner cell mass in controlling implantation in the mouse [PDF]

Reproduction, 1976
Summary. Studies with mouse blastocysts and trophoblastic vesicles showed that the inner cell mass was not essential for controlling trophoblast activity during delay of implantation.
M H, Snow, J, Aitken, J D, Ansell
openaire   +2 more sources

RAF kinase activity regulates neuroepithelial cell proliferation and neuronal progenitor cell differentiation during early inner ear development [PDF]

, 2010
Background: Early inner ear development requires the strict regulation of cell proliferation, survival, migration and differentiation, coordinated by the concerted action of extrinsic and intrinsic factors.
Rapp Ulf R., Marta Magariños, Varela-Nieto, Isabel, Hortensia Sánchez-Calderón, Aburto María R., Muñoz-Agudo, Carmen, Muñoz-Agudo Carmen, Rapp, Ulf Rüdiger, Rodriguez Aburto, Maria, María R. Aburto, Magariños Marta, María R Aburto, Sánchez-Calderón, Hortensia, Rapp, Ulf R., Ulf R Rapp, Isabel Varela-Nieto, Varela-Nieto Isabel, Magariños, Marta, Carmen Muñoz-Agudo, Sánchez-Calderón Hortensia, Ulf R. Rapp, Muñoz Agudo, Carmen   +21 more
core   +2 more sources

Position- and Hippo signaling-dependent plasticity during lineage segregation in the early mouse embryo

eLife, 2017
The segregation of the trophectoderm (TE) from the inner cell mass (ICM) in the mouse blastocyst is determined by position-dependent Hippo signaling. However, the window of responsiveness to Hippo signaling, the exact timing of lineage commitment and the
Eszter Posfai, Sophie Petropoulos, Flavia Regina Oliveira de Barros, John Paul Schell, Igor Jurisica, Rickard Sandberg, Fredrik Lanner, Janet Rossant   +7 more
doaj   +1 more source

Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass. [PDF]

Nat Commun, 2017
X-chromosome inactivation is established during early development. In mice, transcriptional repression of the paternal X-chromosome (Xp) and enrichment in epigenetic marks such as H3K27me3 is achieved by the early blastocyst stage.
Borensztein M, Okamoto I, Syx L, Guilbaud G, Picard C, Ancelin K, Galupa R, Diabangouaya P, Servant N, Barillot E, Surani A, Saitou M, Chen CJ, Anastassiadis K, Heard E.   +14 more
europepmc   +3 more sources

A developmental insurance policy

eLife, 2017
Why does a totipotent state linger within the inner cell mass of mouse embryos?
Nestor Saiz, Anna-Katerina Hadjantonakis
doaj   +1 more source

Day-3-embryo fragmentation is associated with singleton birth weight following fresh single blastocyst transfer: A retrospective study

Frontiers in Endocrinology, 2022
BackgroundPrevious studies have arguably associated poor embryo morphology with low birth weight in singletons following single embryo transfer. However, the association between birth weight and specific morphological features in the cleavage stage ...
Jiali Cai, Jiali Cai, Lanlan Liu, Lanlan Liu, Jinghua Chen, Zhenfang Liu, Xiaoming Jiang, Haixiao Chen, Jianzhi Ren   +8 more
doaj   +1 more source