Results 1 to 10 of about 3,321 (117)

Tracking changes of the parameters of glucose-insulin homeostasis during the course of obesity in B6D2F1 mice [PDF]

Heliyon, 2020
Obesity is one of the primary causes of type 2 diabetes mellitus (T2DM). To better understand how obesity impairs glucose-insulin homeostasis, we tracked fasting blood glucose and insulin levels and the key components of glucose-insulin homeostasis for 7
Sakineh Esmaeili Mohsen Abadi, Ramin Balouchzadeh, Guney Uzun, Hoo Sang Ko, H. Felix Lee, Sarah Park, Guim Kwon   +6 more
doaj   +2 more sources

Inheritance of Steroid-Independent Male Sexual Behavior in Male Offspring of B6D2F1 Mice [PDF]

Hormones and Behavior, 2016
Emilie Rissman, Christine M McInnis, Jin Ho Park   +2 more
exaly   +2 more sources

Androgen- and Estrogen-Independent Regulation of Copulatory Behavior Following Castration in Male B6D2F1 Mice [PDF]

Hormones and Behavior, 2009
Emilie Rissman, Jin Ho Park
exaly   +2 more sources

TNFα Blockade Inhibits Both Initial and Continued Control of Pulmonary Coccidioides

Frontiers in Cellular and Infection Microbiology, 2022
Tumor necrosis factor alpha (TNFα) is a pluripotent cytokine that is important in many infections, though its role in Coccidioides infection remains poorly understood.
Daniel A. Powell, Daniel A. Powell, Lisa F. Shubitz, Christine D. Butkiewicz, Hien T. Trinh, Fariba M. Donovan, Fariba M. Donovan, Jeffrey A. Frelinger, John N. Galgiani, John N. Galgiani   +9 more
doaj   +1 more source

Compound A Increases Cell Infiltration in Target Organs of Acute Graft-versus-Host Disease (aGVHD) in a Mouse Model

Molecules, 2021
Systemic steroids are used to treat acute graft-versus-host disease (aGVHD) caused by allogenic bone marrow transplantation (allo-BMT); however, their prolonged use results in complications. Hence, new agents for treating aGVHD are required.
Abdellatif Bouazzaoui, Ahmed A. H. Abdellatif, Faisal A. Al-Allaf, Neda M. Bogari, Mohiuddin M. Taher, Mohammad Athar, Thomas Schubert, Turki M. Habeebullah, Sameer H. Qari   +8 more
doaj   +1 more source

Anti-E. coli Immunoglobulin Yolk (IgY): Reduction of pathogen receptors and inflammation factors could be caused by decrease in E. coli load

Heliyon, 2023
Graft versus host disease (GVHD) remains the major cause of morbidity and mortality after allogeneic stem cell transplantation, especially for intestinal GVHD, as steroid resistant GVHD results in high mortality.
Abdellatif Bouazzaoui, Neda M. Bogari, Faisal A. Al-Allaf, Samar N. Ekram, Mohammad Athar, Anas Dannoun, Thomas Schubert, Shahzad N. Syed, Abdel-Rahman Youssef, Mashael Alqahtani, Ahmed A.H. Abdellatif   +10 more
doaj   +1 more source

The effects of secondary iron overload and iron chelation on a radiation-induced acute myeloid leukemia mouse model

BMC Cancer, 2021
Background Patients with myelodysplastic syndrome (MDS) require chronic red blood cell (RBC) transfusion due to anemia. Multiple RBC transfusions cause secondary iron overload and subsequent excessive generation of reactive oxygen species (ROS), which ...
Lap Shu Alan Chan, Lilly ChunHong Gu, Richard A. Wells   +2 more
doaj   +1 more source

Defibrotide modulates pulmonary endothelial cell activation and protects against lung inflammation in pre-clinical models of LPS-induced lung injury and idiopathic pneumonia syndrome

Frontiers in Immunology, 2023
IntroductionA multiple organ dysfunction syndrome (MODS) workshop convened by the National Institute of Child Health and Human Development in 2015 identified acute respiratory distress syndrome (ARDS) and complications of allogeneic blood and marrow ...
Orly R. Klein, Yiouli P. Ktena, Elizabeth Pierce, Han-Hsuan Fu, Azeb Haile, Chen Liu, Kenneth R. Cooke   +6 more
doaj   +1 more source

Effect of Different Volume of Microdrop Culture on B6D2F1 Mice Oogenesis

Journal of Animal Reproduction and Biotechnology, 2016
This study was conducted to evaluate the effects of different volume (100 μl vs. 2 ml) of microdrop culture on B6D2F1 mice oogenesis. In the present study, B6D2F1/CrljOri F1 mice were utilized in order to maximize oogenesis.
Chang-Seok Yoo, Kee Sang Park, Byoung Boo Seo   +2 more
doaj   +1 more source

Increased dendritic spine density and tau expression are associated with individual differences in steroidal regulation of male sexual behavior. [PDF]

PLoS ONE, 2013
Male sexual behavior (MSB) is modulated by gonadal steroids, yet this relationship is highly variable across species and between individuals. A significant percentage (~30%) of B6D2F1 hybrid male mice demonstrate MSB after long-term orchidectomy (herein ...
Pranay Bharadwaj, Christine McInnis, Amanda M K Madden, Paul J Bonthuis, Susan Zup, Emilie F Rissman, Jin Ho Park   +6 more
doaj   +1 more source