Results 11 to 20 of about 1,188,690 (195)

Effects of Six Sequential Charged Particle Beams on Behavioral and Cognitive Performance in B6D2F1 Female and Male Mice [PDF]

Frontiers in Physiology, 2020
The radiation environment astronauts are exposed to in deep space includes galactic cosmic radiation (GCR) with different proportions of all naturally occurring ions.
Jacob Raber, Jacob Raber, Andrea Fuentes Anaya, Eileen Ruth S. Torres, Joanne Lee, Sydney Boutros, Dmytro Grygoryev, Austin Hammer, Kristin D. Kasschau, Thomas J. Sharpton, Thomas J. Sharpton, Mitchell S. Turker, Amy Kronenberg   +12 more
doaj   +7 more sources

16Oxygen irradiation enhances cued fear memory in B6D2F1 mice [PDF]

Life Sciences in Space Research, 2015
The space radiation environment includes energetic charged particles that may impact cognitive performance. We assessed the effects of (16)O ion irradiation on cognitive performance of C57BL/6J × DBA/2J F1 (B6D2F1) mice at OHSU (Portland, OR) one month following irradiation at Brookhaven National Laboratory (BNL, Upton, NY).
Raber, Jacob, Marzulla, Tessa, Kronenberg, Amy, Turker, Mitchell S   +3 more
openaire   +6 more sources

Effect of OVOIL oil on B6D2F1 Mice Oogenesis

Journal of Animal Reproduction and Biotechnology, 2018
This study was performed to investigate the effect of types of oil (OVOIL vs. OIL) on B6D2F1 mice oogenesis. In this study, B6D2F1 F1 mice were used in order to maximize oogenesis. The expansion rate of cumulus cells (82.0%±0.2 vs.
Dan-Bi Lee, Kee Sang Park, Byoung Boo Se
doaj   +3 more sources

Effect of Type of Culture Media on B6D2F1 Mice Oogenesis

Journal of Animal Reproduction and Biotechnology, 2016
This study was conducted to evaluate the effects of type of culture media (BM, G2, OS, TCM, and MEM) on B6D2F1 mice oogenesis. In the present study, B6D2F1/CrljOri F1 mice were utilized in order to maximize oogenesis.
Chang-Seok Yoo, Kee Sang Park, Byoung Boo Seo   +2 more
doaj   +2 more sources

Effect of Transfer Temperature of Epididymis on Survival Rate of Semen and B6D2F1 Mice Developmental Capacity

Journal of Animal Reproduction and Biotechnology, 2016
This study was conducted to evaluate the effect of transfer temperature of epididymis on survival rate of semen and development ability of B6D2F1 mice embryos. No significant differences were noted in the survival rate of semen (59.0% ± 0.1 vs. 47.6% ± 0.
Dan-Bi Lee, Kee Sang Park, Byoung Boo Seo   +2 more
doaj   +2 more sources

Combined Effects of Three High-Energy Charged Particle Beams Important for Space Flight on Brain, Behavioral and Cognitive Endpoints in B6D2F1 Female and Male Mice [PDF]

Frontiers in Physiology, 2019
The radiation environment in deep space includes the galactic cosmic radiation with different proportions of all naturally occurring ions from protons to uranium.
Jacob Raber, Jacob Raber, Jacob Raber, Joy Yamazaki, Eileen Ruth S. Torres, Nicole Kirchoff, Keaton Stagaman, Thomas Sharpton, Thomas Sharpton, Mitchell S. Turker, Mitchell S. Turker, Amy Kronenberg   +11 more
doaj   +2 more sources

Dichotomous mechanisms of aortic stiffening in high-fat diet fed young and old B6D2F1 mice. [PDF]

Physiol Rep, 2014
Abstract Advancing age is associated with increased stiffness of large elastic arteries as assessed by aortic pulse wave velocity (PWV). Greater PWV, associated with increased risk of cardiovascular diseases, may result from altered expression of the extracellular matrix proteins, collagen and elastin, as well as cross-linking of proteins by advanced ...
Henson GD, Walker AE, Reihl KD, Donato AJ, Lesniewski LA.   +4 more
europepmc   +4 more sources

Bone Marrow Failure Model Mimics Aplastic Anemia Patients: Single-Cell Landscape of Immune Response Reveals Novel Mechanisms of Immune Imbalance in AA. [PDF]

Cancer Med
Single‐cell RNA‐seq is used in a mouse model of immune‐mediated bone marrow failure. Approach to platelets and mitochondrial data. Analysis of various immune cell landscapes, interactions and driving factors in BMF, involving platelets, CD4+ T Cells, CD8+ T Cells, macrophages, and mitochondrial energy metabolism pathways.
Tan S, Fang F, Sun J, Li Y, Chen Y, Sun W.   +5 more
europepmc   +2 more sources

Efficient Derivation and Transcriptional Characterization of Mouse Extra-Embryonic Endoderm Stem Cell Lines Generated by Somatic Cell Nuclear Transfer. [PDF]

Stem Cells Int
Somatic cell nuclear transfer (SCNT) holds great promise for regenerative medicine and agriculture, but its application is severely hampered by low efficiency, primarily attributable to aberrant epigenetic reprogramming. Although embryonic stem cells (ESCs) and trophoblast stem cells (TSCs) have been successfully derived from cloned embryos, an in ...
Li S, Wei S, Li G, Hu M, Lin J, Bao W.
europepmc   +2 more sources

The Immunoregulatory and Hematopoietic Effects of Momelotinib in a Murine Bone Marrow Failure Model. [PDF]

J Clin Lab Anal
Momelotinib, a selective small‐molecule inhibitor of JAK1/2 and the bone morphogenic protein receptor kinase activin A receptor type I (ACVR1), exerts its effects by inhibiting the overactivation of the BMP/ACVR1/SMAD signaling pathway. This inhibition reduces hepcidin production in hepatocytes, and reduces inflammation, aberrant cytokine signaling ...
Zhang Y, Zhang H, Hu N, Yang L, Liu Y, Yang L, Dong X, Wang H.   +7 more
europepmc   +2 more sources