Results 1 to 10 of about 2,296 (70)

Metabolomics in Prenatal Medicine: A Review

open access: yesFrontiers in Medicine, 2021
Pregnancy is a complicated and insidious state with various aspects to consider, including the well-being of the mother and child. Developing better non-invasive tests that cover a broader range of disorders with lower false-positive rates is a ...
Giovanni Monni   +7 more
doaj   +1 more source

Traf4 is required for tight junction complex during mouse blastocyst formation

open access: yesJournal of Animal Reproduction and Biotechnology, 2021
Traf4 (Tumor necrosis factor Receptor Associated Factor 4) is a member of the tumor necrosis factor receptor (TNFR) - associated factors (TRAFs) family.
Jian Lee, Inchul Choi
doaj   +1 more source

SIN3A Regulates Porcine Early Embryonic Development by Modulating CCNB1 Expression

open access: yesFrontiers in Cell and Developmental Biology, 2021
SIN3A is the central scaffold protein of the SIN3/histone deacetylase (HDAC) transcriptional repressor complex. SIN3A participates in the mouse preimplantation development by fine-tuning HDAC1 expression. However, it remains unresolved if this functional
Lei Luo   +6 more
doaj   +1 more source

Comparison of cell lineage development and regulation during early embryonic development in cattle and mice

open access: yes浙江大学学报. 农业与生命科学版, 2023
Low reproductive efficiency of high-yielding dairy cows is a worldwide challenge, among which the high mortality rate of early embryos is one of the main reasons.
WU Xiaotong   +4 more
doaj   +1 more source

Chromatin dynamics through mouse preimplantation development revealed by single molecule localisation microscopy

open access: yesBiology Open, 2022
Most studies addressing chromatin behaviour during preimplantation development are based on biochemical assays that lack spatial and cell-specific information, crucial during early development.
Marta Portela   +6 more
doaj   +1 more source

Overlapping functions of RBBP4 and RBBP7 in regulating cell proliferation and histone H3.3 deposition during mouse preimplantation development

open access: yesEpigenetics, 2022
Preimplantation development is critical for reproductive successes in mammals. Thus, it is important to understand how preimplantation embryogenesis is regulated.
Lieying Xiao   +6 more
doaj   +1 more source

Selecting Normalizers for MicroRNA RT-qPCR Expression Analysis in Murine Preimplantation Embryos and the Associated Conditioned Culture Media

open access: yesJournal of Developmental Biology, 2023
Normalizing RT-qPCR miRNA datasets that encompass numerous preimplantation embryo stages requires the identification of miRNAs that may be used as stable reference genes.
David C. Hawke   +2 more
doaj   +1 more source

Functions of developmental pluripotency-associated 2 and 4 (DPPA2/DPPA4) in bovine preimplantation embryo development and their potential mechanisms

open access: yes浙江大学学报. 农业与生命科学版, 2023
Developmental pluripotency-associated 2 and 4 (DPPA2/DPPA4) are important regulators of genome activation in 2-cell-like embryonic stem cells (2CL ESCs), meanwhile, they can regulate the proliferation of ESCs. However, the functions of DPPA2/DPPA4 during
QIU Jinlong   +7 more
doaj   +1 more source

Human embryo polarization requires PLC signaling to mediate trophectoderm specification

open access: yeseLife, 2021
Apico-basal polarization of cells within the embryo is critical for the segregation of distinct lineages during mammalian development. Polarized cells become the trophectoderm (TE), which forms the placenta, and apolar cells become the inner cell mass ...
Meng Zhu   +20 more
doaj   +1 more source

Differential Signals From TNFα-Treated and Untreated Embryos in Uterine Tissues and Splenic CD4+ T Lymphocytes During Preimplantation Pregnancy in Mice

open access: yesFrontiers in Veterinary Science, 2021
The main aim of this study was to examine if a female mouse body in preimplantation pregnancy can distinguish between embryos of normal and impaired biological quality in the local and peripheral compartments.
Katarzyna Buska-Mach   +12 more
doaj   +1 more source

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