Results 21 to 30 of about 2,389 (154)
Background: Seminal plasma (SP) promotes sperm survival and fertilizing capacity, and potentially affects embryo development, presumably via specific signaling pathways to the internal female genital tract.Objectives: This study evaluated how ...
Cristina A. Martinez +23 more
doaj +1 more source
The segregation of the trophectoderm (TE) from the inner cell mass (ICM) in the mouse blastocyst is determined by position-dependent Hippo signaling. However, the window of responsiveness to Hippo signaling, the exact timing of lineage commitment and the
Eszter Posfai +7 more
doaj +1 more source
Which Stage of Mouse Embryos Is More Appropriate for Vitrification? [PDF]
Background Vitrification has been shown as one of the most effective methods of cryopreservation for mammalian embryos. However, there is no consensus which stage of embryonic development is the most appropriate for vitrification with subsequent maximal ...
Nasibeh Ghandy +1 more
doaj +1 more source
Preimplantation Stress and Development [PDF]
The developmental origins of health and disease hypothesis holds that inappropriate environmental cues in utero, a period marked by tremendous developmental sensitivity, facilitate cellular reprogramming to ultimately predispose disease in adulthood. In this review, we analyze if stress during early stages of development can affect future health.
Feuer, Sky, Rinaudo, Paolo
openaire +4 more sources
Seminal Fluid Metabolomic Markers of Oligozoospermic Infertility in Humans
Infertility affects 12−15% of couples worldwide, and male factors are the cause of nearly half of all cases. Studying seminal fluid composition could lead to additional diagnostic accuracy and a better understanding of the pathophysiology of male ...
Federica Murgia +9 more
doaj +1 more source
Expression Profile of Developmentally Important Genes in preand peri-Implantation Goat Embryos Produced In Vitro [PDF]
Background: Little is understood about the regulation of gene expression during early goat embryo development. This study investigated the expression profile of 19 genes, known to be critical for early embryo development in mouse and human, at five ...
Pouria HosseinNia +6 more
doaj +1 more source
Persistence of a fetal thickened nuchal translucency (NT), one of the most sensitive and specific individual markers of fetal disorders, is strongly correlated with the possibility of a genetic syndrome, congenital infections, or other malformations ...
Federica Murgia +7 more
doaj +1 more source
MERVL/Zscan4 Network Activation Results in Transient Genome-wide DNA Demethylation of mESCs
Mouse embryonic stem cells are dynamic and heterogeneous. For example, rare cells cycle through a state characterized by decondensed chromatin and expression of transcripts, including the Zscan4 cluster and MERVL endogenous retrovirus, which are usually ...
Mélanie A. Eckersley-Maslin +12 more
doaj +1 more source
Preimplantation HLA Testing [PDF]
Preimplantation genetic diagnosis (PGD) has become an option for couples for whom termination of an affected pregnancy identified by traditional prenatal diagnosis is unacceptable and is applicable to indications beyond those of prenatal diagnosis, such as HLA matching to affected siblings to provide stem cell transplantation.To describe ...
Yury, Verlinsky +5 more
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Preimplantation Genetic Diagnosis
Preimplantation genetic diagnosis or screening is a very early form of prenatal diagnosis that allows embryos to be tested for genetic disorders before pregnancy has begun. The procedure offers an advantage for couples with genetic disorders whose offspring has an increased risk of a specific genetic condition by helping in the delivery of a healthy ...
Pavelić, Krešimir +1 more
openaire +1 more source

