Results 41 to 50 of about 2,389 (154)

Electroclinical features and dynamic network connectivity of orbitofrontal epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Orbitofrontal epilepsy (OFE) is rare and underrecognized. This study aims to characterize electroclinical features and dynamic network connectivity of OFE and subtypes. Methods We retrospectively analyzed 17 patients with OFE who underwent stereoelectroencephalographic (SEEG) electrode implantation and epilepsy surgery at our center.
Meixuan Ren   +13 more
wiley   +1 more source

A developmental insurance policy

open access: yeseLife, 2017
Why does a totipotent state linger within the inner cell mass of mouse embryos?
Nestor Saiz, Anna-Katerina Hadjantonakis
doaj   +1 more source

Legal Regulation of Preimplantation Genetic Diagnosis: A Comparative Analysis of the Baltic Sea Region and the Nordic Countries

open access: yesTeisė, 2022
This paper examines the concept and regulation of some of the latest research in the field of fertility – preimplantation genetic diagnosis – in Lithuania, Poland, the Baltic States, and the Nordic countries.
Nastė Grubliauskienė
doaj   +1 more source

Perils and progress in epilepsy surgery utilization: Twenty‐five years later

open access: yesEpilepsia, EarlyView.
Abstract More than 25 years have passed since the first randomized controlled trial (RCT) established that surgery is superior to continued anti‐seizure medication (ASM) for drug‐resistant temporal lobe epilepsy, and nearly as long since a joint practice parameter urged that appropriate surgical candidates be referred to a specialized center for ...
Dario J. Englot
wiley   +1 more source

Preimplantation Genetic Diagnosis

open access: yesAMA Journal of Ethics, 2001
Preimplantation genetic diagnosis raises ethical and moral concerns about using one person as a means to save another, especially as highlighted in recent cases where parents have more children in the hopes of saving a sick child. Virtual Mentor is a monthly bioethics journal published by the American Medical Association.
openaire   +2 more sources

Bridging computational and clinical strategies for presurgical identification of epileptogenic networks

open access: yesEpilepsia Open, EarlyView.
Abstract Objective About one third of epilepsy patients are drug‐resistant. Resective epilepsy surgery remains a key treatment option but depends critically on accurate identification of the seizure onset zone (SOZ), which is still guided mainly by subjective visual inspection of electrophysiological signals.
Tena Dubcek   +5 more
wiley   +1 more source

Maternal SMCHD1 controls both imprinted Xist expression and imprinted X chromosome inactivation

open access: yesEpigenetics & Chromatin, 2022
Embryonic development is dependent on the maternal supply of proteins through the oocyte, including factors setting up the adequate epigenetic patterning of the zygotic genome.
Iromi Wanigasuriya   +9 more
doaj   +1 more source

The effect of ovarian stimulation protocol on follicular asynchrony during in vitro fertilization – A retrospective cohort study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To examine the effect of controlled ovarian stimulation (COS) protocol on follicular synchrony in a subsequent in vitro fertilization (IVF) cycle in patients whose previous cycle was canceled due to asynchrony. Methods A single‐center retrospective‐cohort study (January 2018–March 2024), including women undergoing IVF who had: (1) a ...
Alyssa Hochberg   +5 more
wiley   +1 more source

H4K20 monomethylation inhibition causes loss of genomic integrity in mouse preimplantation embryos

open access: yesThe Journal of Reproduction and Development, 2020
Maintaining genomic integrity in mammalian early embryos, which are deficient in DNA damage repair, is critical for normal preimplantation and subsequent development.
Daiki SHIKATA   +4 more
doaj   +1 more source

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

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