Results 61 to 70 of about 44,045 (236)

H4K20 monomethylation inhibition causes loss of genomic integrity in mouse preimplantation embryos

The Journal of Reproduction and Development, 2020
Maintaining genomic integrity in mammalian early embryos, which are deficient in DNA damage repair, is critical for normal preimplantation and subsequent development.
Daiki SHIKATA, Takuto YAMAMOTO, Shinnosuke HONDA, Shuntaro IKEDA, Naojiro MINAMI   +4 more
doaj   +1 more source

The Preimplantation Embryo: Handle with Care [PDF]

Seminars in Reproductive Medicine, 2008
The past decade has seen considerable advances in our understanding of intrinsic developmental mechanisms associated with gametogenesis and embryogenesis and accompanying applications in the fields of reproductive medicine, embryonic stem cell biology, and nuclear reprogramming.
Watkins, Adam J., Papenbrock, Tom, Fleming, Tom P.   +2 more
openaire   +3 more sources

How much does the reduced electroencephalographic montage matter for seizure detection? A large‐cohort simulation study

Epilepsia, EarlyView.
Abstract Objective Subscalp electroencephalographic (EEG) systems with few channels have emerged as promising solutions for ultra‐long‐term seizure monitoring, but the impact of montage configuration on automated seizure detection is unclear. We compared automated detection performance between full‐scalp and simulated reduced montages approximating ...
Joe Kojima, Haoer Shi, Svanik Jaikumar, William K. S. Ojemann, Carlos Aguila, Juri Kim, Taneeta Mindy Ganguly, Brian Litt, Erin C. Conrad   +8 more
wiley   +1 more source

Preimplantation genetic testing for aneuploidy in uterus transplant patients

Therapeutic Advances in Reproductive Health, 2021
Uterus transplantation is an emerging treatment for uterine factor infertility. In vitro fertilization with cryopreservation of embryos prior is required before a patient can be listed for transplant.
Rhea Chattopadhyay, Elliott Richards, Valerie Libby, Rebecca Flyckt   +3 more
doaj   +1 more source

Predictive Factors for Recovery Time in Conceived Women Suffering From Moderate to Severe Ovarian Hyperstimulation Syndrome

Frontiers in Endocrinology, 2022
ObjectiveThis study aimed to evaluate potential predictors for recovery time in pregnant patients with moderate to severe ovarian hyperstimulation syndrome (OHSS).MethodsA total of 424 pregnant patients with moderate to severe OHSS who underwent in vitro
Kai Huang, Ying Shi, Gezi Chen, Hao Shi, Jun Zhai   +4 more
doaj   +1 more source

The effect of ovarian stimulation protocol on follicular asynchrony during in vitro fertilization – A retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To examine the effect of controlled ovarian stimulation (COS) protocol on follicular synchrony in a subsequent in vitro fertilization (IVF) cycle in patients whose previous cycle was canceled due to asynchrony. Methods A single‐center retrospective‐cohort study (January 2018–March 2024), including women undergoing IVF who had: (1) a ...
Alyssa Hochberg, Maria Hincapie, Uri Amikam, Nir Kugelman, William Buckett, Shauna Reinblatt   +5 more
wiley   +1 more source

Alternative splicing signatures in preimplantation embryo development

Cell & Bioscience, 2020
Background Preimplantation embryo development is a highly ordered sequence of processes and it requires a precise temporal and spatial control of gene expression.
Geng G. Tian, Jing Li, Ji Wu
doaj   +1 more source

Preimplantation diagnosis for neurofibromatosis

Reproductive BioMedicine Online, 2002
Preimplantation genetic diagnosis (PGD) has recently been performed for inherited cancer predisposition determined by p53 tumour suppressor gene mutations, suggesting the usefulness of PGD for late onset disorders with genetic predisposition, including those caused by the germline mutations of other tumour suppressor genes.
Yury, Verlinsky, Svetlana, Rechitsky, Oleg, Verlinsky, Anna, Chistokhina, Tatyana, Sharapova, Christina, Masciangelo, Michael, Levy, Brian, Kaplan, Kevin, Lederer, Anver, Kuliev   +9 more
openaire   +2 more sources

Breakpoint Mapping and Disrupted Gene Identification in Azoospermic Patients With Chromosomal Balanced Translocation by Nanopore Sequencing

Journal of Clinical Laboratory Analysis, EarlyView.
This study employed nanopore long‐read sequencing to achieve single‐base‐pair resolution breakpoint mapping in azoospermic patients with chromosomal balanced translocations, revealing cryptic breakpoints and an inverted insertion undetectable by conventional karyotyping.
Jian Zhang, Xiao‐lu Chen, Jia‐yan Chen, Yun‐sheng Ge   +3 more
wiley   +1 more source

Chromosome segregation and recombination in human meiosis: Clinical applications and insight into disjunction errors [PDF]

, 2015
Chromosome copy number errors (or aneuploidy) of gametes and embryos occurs in humans more frequently than in any other studied species, with a spectrum of manifestations from implantation failure to affected live births.
Ottolini, Christian Simon, The Bridge Centre Ltd, UK   +1 more
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