Results 81 to 90 of about 2,389 (154)
Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley +1 more source
Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone +1 more
wiley +1 more source
ABSTRACT Fructose‐1,6‐bisphosphatase deficiency is a rare inherited metabolic disorder of gluconeogenesis characterized by recurrent hypoglycemia and lactic acidosis, typically triggered by inadequate glucose intake or increased consumption of fructose, sucrose, or sorbitol.
Raashda A. Sulaiman +6 more
wiley +1 more source
Cochlear Implantation in Autoimmune Inner‐Ear Disease: Outcome and Patient‐Reported Benefit
This study demonstrates that patients with secondary autoimmune inner‐ear disease (AIED) achieve significant improvements in speech perception and quality of life following cochlear implantation. Although AIED patients may show slightly lower performance in noisy environments compared to controls, their subjective hearing benefit converges with matched
Merete Hartmann +4 more
wiley +1 more source
Prenatal Genomics for Sonographers: Enhancing Confidence, Communication, and Clinical Care
ABSTRACT Genomic medicine is advancing rapidly, bringing significant changes to prenatal care and expanding the role of health professionals. As clinicians responsible for performing prenatal ultrasounds which may detect fetal anomalies and ultimately lead to genetic diagnoses, sonographers should have an understanding of genomic concepts to support a ...
Deborah Wye +2 more
wiley +1 more source
New perspectives on preimplantation genetic diagnosis and preimplantation genetic screening
Preimplantation genetic diagnosis is a procedure that involves the removal of one or more nuclei from oocytes (a polar body) or embryos (blastomeres or trophectoderm cells) in order to test for problems in genome sequence or chromosomes of the embryo prior to implantation.
Chun-Kai Chen +3 more
openaire +3 more sources
Long-chain fatty acid β-oxidation regulates embryonic development by H3K18 acetylation in mice
Fatty acids are not only important as energy sources, but also playing crucial roles in maintaining cellular homeostasis. However, their role in preimplantation development remains unclear. Here, we find that fatty acids gradually accumulate after 4-cell
Kefan Zheng +7 more
doaj +1 more source
Advanced maternal age impairs uterine decidualization via downregulated RICTOR‐ATK3‐FoxO1 signaling. The RICTOR agonist MHY1485 rescues decidual defects, offering a therapy for age‐related pregnancy failure. ABSTRACT Miscarriage and abnormal embryonic development in women of advanced maternal age (AMA) are often associated with impaired decidualization.
Yifeng Lin +9 more
wiley +1 more source
ABSTRACT Background Advanced paternal age is associated with reduced male fertility and testicular dysfunction. Among the molecular regulators involved in aging, SIRT1, a NAD+‐dependent deacetylase, plays a pivotal role in maintaining oxidative balance and cellular homeostasis.
María Iniesta‐Cuerda +7 more
wiley +1 more source
ABSTRACT Background Sperm acquire fertility ability during epididymal maturation mainly in the epididymal caput and corpus, and once matured, are stored in the epididymal cauda. During storage, interactions with cauda epididymosomes (epEVs) may influence sperm fertility potential; however, the role of such interactions on sperm fertility remains ...
Maíra Bianchi Rodrigues Alves +7 more
wiley +1 more source

