Results 81 to 90 of about 44,045 (236)
Banking Biodiversity: Ex Vivo Solutions for a Planet in Crisis
Zoo Biology, EarlyView.Genetic diversity is being lost faster than it can be cataloged. Biobanking preserves cells, gametes, and DNA as recoverable material for future conservation use, and delivers most when collections are established proactively rather than deployed once populations are already critically depleted.
Oz Pomp, Nicole Tay, Shangzhe Xie
wiley +1 more source
Transcriptome activity of isochores during preimplantation process in human and mouse [PDF]
, 2016 This work investigates the role of isochores during preimplantation process. Using RNA-seq data from human and mouse preimplantation stages, we created the spatio-temporal transcriptional profiles of the isochores during preimplantation.
Carl Barton +7 more
core +1 more source
eLifeLoss of maternal SETDB1, a histone H3K9 methyltransferase, leads to developmental arrest prior to implantation, with very few mouse embryos advancing beyond the eight-cell stage, which is currently unexplained. We genetically investigate SETDB1’s role in
Tie-Bo Zeng +5 more
doaj +1 more source
Reproductive Challenges of the Ageing Female: A Comprehensive Narrative Review
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT Changes in societal norms over the last few decades have resulted in novel family planning trends, notably delayed childbearing and increased maternal age at the birth of the first child. Despite advances in reproductive medicine, ageing poses significant challenges.
Sofia Bitzika +6 more
wiley +1 more source
Frontiers in Genetics, 2019 Preimplantation genetic testing for the monogenic disorder (PGT-M) spinal muscular atrophy (SMA) is significantly improved by supplementation of SMN1 deletion detection with marker-based linkage analysis. To expand the availability of informative markers
Mingjue Zhao +8 more
doaj +1 more source
A Spotlight on Yolk‐sac Tumors: Molecular Pathology, Current Diagnostics, and Novel Therapeutics
Andrology, EarlyView.ABSTRACT Background Yolk‐sac tumors are an aggressive subtype of testicular cancer that significantly contribute to disease progression and therapy resistance, especially in adults. While testicular cancer generally has high cure rates with cisplatin‐based treatment, adult yolk‐sac tumors often appear as components of mixed tumors with poor response to
Evangelos Prokakis +3 more
wiley +1 more source
Prevention of Leber congenital amaurosis through preimplantation genetic diagnosis
, 2018 © 2018 American Association for Pediatric Ophthalmology and Strabismus Preimplantation genetic diagnosis can allow a family with a hereditary genetic mutation to conceive a disease-free child.
Fox, J. E. +7 more
core +1 more source
Andrology, EarlyView.ABSTRACT Background A large number of children have been born using testicular sperm from men with Klinefelter syndrome (KS), whereas reports of children conceived using ejaculated sperm are rare. Objective To review all published cases of children conceived using ejaculated sperm from men with KS, assess their health and karyotype, and evaluate ...
Jens Fedder, Freja Sørensen
wiley +1 more source
Non-invasive and invasive preimplantation genetic testing workflow.
, 2018 Non-invasive and invasive preimplantation genetic testing workflow.
Ran Antes (417275) +6 more
core +1 more source
, 2013 The preimplantation mammalian embryo is sensitive to the environment in which they develop and grow, either in vivo or in vitro. Disturbance to embryo environmental conditions can affect embryo growth.
Bakheet, Ayat
core +1 more source