Results 51 to 60 of about 44,045 (236)
ViTAMIn‐O: Democratizing Computer Vision‐Based Machine Learning for Stem Cell Research
Advanced Intelligent Systems, EarlyView.This study introduces a fully open generalist computer vision model for predicting the differentiation outcomes of stem cell‐based model systems, together with its code‐free deployment platform, ColabViTAMIn‐O. It is benchmarked against various architectures, datasets, and training protocols.
Ferhat Hamurcu +11 more
wiley +1 more source
A developmental insurance policy
eLife, 2017 Why does a totipotent state linger within the inner cell mass of mouse embryos?
Nestor Saiz, Anna-Katerina Hadjantonakis
doaj +1 more source
Teisė, 2022 This paper examines the concept and regulation of some of the latest research in the field of fertility – preimplantation genetic diagnosis – in Lithuania, Poland, the Baltic States, and the Nordic countries.
Nastė Grubliauskienė
doaj +1 more source
Preimplantation Diagnosis of Thalassemias [PDF]
Journal of Assisted Reproduction and Genetics, 1998 Preimplantation genetic diagnosis (PGD) is an important option for couples at risk of having children with beta-globin mutations to avoid selective abortions of affected fetuses following prenatal diagnosis.We performed PGD for thalassemia in 12 clinical cycles (IVS1-110, and IVS-745 mutations) using biopsy of the first and second polar bodies (PBs ...
A, Kuliev +10 more
openaire +2 more sources
Annals of Neurology, EarlyView.Objective Memory impairment is a frequent comorbidity of focal epilepsy, incompletely explained by seizure frequency or structural pathology. Ictal and postictal hippocampal dysfunction disrupt memory processes, but their cumulative impact remains poorly quantified.
Ionuț‐Flavius Bratu +5 more
wiley +1 more source
X Chromosome Inactivation Is Initiated in Human Preimplantation Embryos [PDF]
, 2009 X chromosome inactivation (XCI) is the mammalian mechanism that compensates for the difference in gene dosage between XX females and XY males. Genetic and epigenetic regulatory mechanisms induce transcriptional silencing of one X chromosome in female ...
Gribnau, Joost +6 more
core +3 more sources
Electroclinical features and dynamic network connectivity of orbitofrontal epilepsy
Epilepsia, EarlyView.Abstract Objective Orbitofrontal epilepsy (OFE) is rare and underrecognized. This study aims to characterize electroclinical features and dynamic network connectivity of OFE and subtypes. Methods We retrospectively analyzed 17 patients with OFE who underwent stereoelectroencephalographic (SEEG) electrode implantation and epilepsy surgery at our center.
Meixuan Ren +13 more
wiley +1 more source
Maternal SMCHD1 controls both imprinted Xist expression and imprinted X chromosome inactivation
Epigenetics & Chromatin, 2022 Embryonic development is dependent on the maternal supply of proteins through the oocyte, including factors setting up the adequate epigenetic patterning of the zygotic genome.
Iromi Wanigasuriya +9 more
doaj +1 more source
Perils and progress in epilepsy surgery utilization: Twenty‐five years later
Epilepsia, EarlyView.Abstract More than 25 years have passed since the first randomized controlled trial (RCT) established that surgery is superior to continued anti‐seizure medication (ASM) for drug‐resistant temporal lobe epilepsy, and nearly as long since a joint practice parameter urged that appropriate surgical candidates be referred to a specialized center for ...
Dario J. Englot
wiley +1 more source
Genetic Normalization of Differentiating Aneuploid Human Embryos [PDF]
, 2011 Early embryogenesis involves a series of dynamic processes, many of which are currently not well described or understood. Aneuploidy and aneuploid mosaicism, a mixture of aneuploid and euploid cells within one embryo, in early embryonic development are ...
Paul Brezina +8 more
core