Results 11 to 20 of about 2,389 (154)
Preimplantation genetic diagnosis
The Lancet, 2004 Preimplantation genetic diagnosis (PGD) was introduced at the beginning of the 1990s as an alternative to prenatal diagnosis, to prevent termination of pregnancy in couples with a high risk for offspring affected by a sex-linked genetic disease. At that time, embryos obtained in vitro were tested to ascertain their sex, and only female embryos were ...
Sermon, Karen +2 more
+11 more sources
Hemoglobinopathies and preimplantation diagnostics
International Journal of Laboratory Hematology, 2022 AbstractHemoglobinopathies constitute some of the most common inherited disorders worldwide. Manifestations are very severe, patient management is difficult and treatment is not easily accessible. Preimplantation genetic testing for monogenic disorders (PGT‐M) is a valuable reproductive option for hemoglobinopathy carrier‐couples as it precludes the ...
Thalia Mamas +3 more
openaire +3 more sources
A Case of Enlarged Intracranial Translucency in a Fetus with Blake’s Pouch Cyst
Case Reports in Obstetrics and Gynecology, 2014 The intracranial translucency (IT) is a recently introduced marker of open spina bifida (OSB). In this study, we describe a case of a fetus affected by Blake’s pouch cyst which showed alterations of BS/BSOB ratio at the first trimester screening.
Ambra Iuculano +3 more
doaj +1 more source
The Journal of Reproduction and Development, 2020 The extracellular matrix between the oocyte and zona pellucida (ZP) plays an important role in mammalian fertilization and preserves the specific environment of the perivitelline space (PVS) during the development of a preimplantation embryo after ...
Hiroka OKAJI +3 more
doaj +1 more source
Color Doppler Score: A New Approach for Monitoring a Large Placental Chorioangioma
Case Reports in Obstetrics and Gynecology, 2014 We employed color Doppler score as an innovative approach for the prenatal diagnosis and monitoring of a large placental chorioangioma case diagnosed at 26 weeks and the subjective semiquantitative assessment of the vascularization.
Maria Angelica Zoppi +7 more
doaj +1 more source
Life, 2020 During the early stages of pregnancy, the uterine endometrium undergoes dramatic morphologic and functional changes accompanied with dynamic variation in gene expression. Pregnancy-stage specific differentially expressed gene (DEG)-transcript-probes were
Mariusz Pierzchała +22 more
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The NR2F2-HAND2 signaling axis regulates progesterone actions in the uterus at early pregnancy
Frontiers in Endocrinology, 2023 Endometrial function is dependent on a tight crosstalk between the epithelial and stromal cells of the endometrium. This communication is critical to ensure a fertile uterus and relies on progesterone and estrogen signaling to prepare a receptive uterus ...
Yeongseok Oh +11 more
doaj +1 more source
Preimplantation genetic diagnosis [PDF]
International Journal of Gynecology & Obstetrics, 2003 Preimplantation genetic diagnosis (PGD) is an exciting new approach for the prevention of transmission of genetic disorders between generations. The use of genetically screened, healthy embryos to establish a pregnancy avoids the need for termination of an affected pregnancy, a procedure which can be traumatic physically and emotionally for potential ...
G-L, Zhuang, J, Deng, D, Zhang
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Epigenetics, 2020 Epigenetic modifications, including DNA methylation and histone modifications, are reprogrammed considerably following fertilization during mammalian early embryonic development.
Panpan Zhao +10 more
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Effects of diabetes between generations on the pre-embryos of rats
Anais da Academia Brasileira de Ciências, 2022 Pregestational hyperglycemia cause adverse effects on mothers and their offspring. We aimed to evaluate the maternal hyperglycemia influence on pre-embryos from diabetic rats and on their generations (daughters and granddaughters).
VINÍCIUS S. BARCO +6 more
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