Results 11 to 20 of about 44,045 (236)

Preimplantation genetic screening [PDF]

Journal of Medical Screening, 2017
Preimplantation genetic diagnosis was first successfully performed in 1989 as an alternative to prenatal diagnosis for couples at risk of transmitting a genetic or chromosomal abnormality, such as cystic fibrosis, to their child. From embryos generated in vitro, biopsied cells are genetically tested.
Joyce C Harper
openaire   +4 more sources

[Preimplantation genetic diagnosis].

Ugeskrift for laeger, 2018
In Denmark, preimplantation genetic diagnosis (PGD) is offered within the public healthcare to families with a known risk of an inherited disease in a child - as an alternative to prenatal diagnosis. It is a well-established technique with rather well-described perinatal- and neonatal outcomes, being comparable to what is seen following in vitro ...
Ingerslev, Hans Jakob, Degn, Birte, Hnida, Christina, Diemer, Tue, Petersen, Michael Bjørn, Olesen, Tine Nørregaard, Krarup, Henrik, Pedersen, Inge Søkilde   +7 more
openaire   +4 more sources

Preimplantation genetic diagnosis

The Lancet, 2004
Preimplantation genetic diagnosis (PGD) was introduced at the beginning of the 1990s as an alternative to prenatal diagnosis, to prevent termination of pregnancy in couples with a high risk for offspring affected by a sex-linked genetic disease. At that time, embryos obtained in vitro were tested to ascertain their sex, and only female embryos were ...
Sermon, Karen, Van Steirteghem, Andre, Liebaers, Ingeborg   +2 more
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Dynamic expression of chromatin modifiers during developmental transitions in mouse preimplantation embryos [PDF]

, 2015
During mouse preimplantation development, major changes in cell fate are accompanied by extensive alterations of gene expression programs. Embryos first transition from a maternal to zygotic program and subsequently specify the pluripotent and the ...
Peters, Antoine H. F. M., Liu, Zichuan, Nestorov, Peter, Hotz, Hans-Rudolf, Peters AH, Liu Z, Hotz HR, Nestorov P   +7 more
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A ‘healthy baby’: The double imperative of preimplantation genetic diagnosis [PDF]

, 2010
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2010 The Authors.This article reports from a study exploring the social processes, meanings and institutions that frame and produce ...
Williams, C, Ehrich, K, Ehrich, Kathryn, Williams, Clare   +3 more
core   +1 more source

Cell arrest and cell death in mammalian preimplantation development [PDF]

, 2011
The causes, modes, biological role and prospective significance of cell death in preimplantation development in humans and other mammals are still poorly understood.
Tuna Güngör, Eckhard Wolf, Güngör Tuna, Horst-Dieter Reichenbach, Leidenfrost, Sandra, Reichenbach, Myriam, Reichenbach Myriam, Leidenfrost Sandra, Reichenbach, Horst-Dieter, Myriam Reichenbach, Sandra Leidenfrost, Marc Boelhauve, Fred Sinowatz, Habermann, Felix A., Felix A Habermann, Wolf Eckhard, Felix A. Habermann, Boelhauve, Marc, Güngör, Tuna, Boelhauve Marc, Wolf, Eckhard, Sinowatz, Fred, Reichenbach Horst-Dieter, Sinowatz Fred, Habermann Felix A.   +24 more
core   +2 more sources

Preimplantation genetic diagnosis [PDF]

International Journal of Gynecology & Obstetrics, 2003
Preimplantation genetic diagnosis (PGD) is an exciting new approach for the prevention of transmission of genetic disorders between generations. The use of genetically screened, healthy embryos to establish a pregnancy avoids the need for termination of an affected pregnancy, a procedure which can be traumatic physically and emotionally for potential ...
G-L, Zhuang, J, Deng, D, Zhang
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Hemoglobinopathies and preimplantation diagnostics

International Journal of Laboratory Hematology, 2022
AbstractHemoglobinopathies constitute some of the most common inherited disorders worldwide. Manifestations are very severe, patient management is difficult and treatment is not easily accessible. Preimplantation genetic testing for monogenic disorders (PGT‐M) is a valuable reproductive option for hemoglobinopathy carrier‐couples as it precludes the ...
Thalia Mamas, Georgia Kakourou, Christina Vrettou, Joanne Traeger‐Synodinos   +3 more
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A Case of Enlarged Intracranial Translucency in a Fetus with Blake’s Pouch Cyst

Case Reports in Obstetrics and Gynecology, 2014
The intracranial translucency (IT) is a recently introduced marker of open spina bifida (OSB). In this study, we describe a case of a fetus affected by Blake’s pouch cyst which showed alterations of BS/BSOB ratio at the first trimester screening.
Ambra Iuculano, Maria Angelica Zoppi, Rosa Maria Ibba, Giovanni Monni   +3 more
doaj   +1 more source

New cellular imaging of oocytes and preimplantation embryos using Lumitein™: Evaluation of oocyte quality and new information on protein dynamics within the perivitelline space during the one-cell oocyte stage in mice

The Journal of Reproduction and Development, 2020
The extracellular matrix between the oocyte and zona pellucida (ZP) plays an important role in mammalian fertilization and preserves the specific environment of the perivitelline space (PVS) during the development of a preimplantation embryo after ...
Hiroka OKAJI, Kenta TETSUKA, Ren WATANABE, Satoshi KISHIGAMI   +3 more
doaj   +1 more source