Results 151 to 160 of about 46,982 (194)

c-JUN enhances CRISPR knockin anti-B7-H3 CAR T cell function in small cell lung cancer and thoracic SMARCA4-deficient undifferentiated tumors. [PDF]

Cell Rep Med
Balke-Want H, Keerthi V, Del Carmen Arenas M, Chen Y, Malipatlolla M, Klysz DD, Xu P, Ho K, Asano K, Stahl D, Huang J, Retherford A, Patel S, Fowler C, Maas L, Gkitsas-Long N, Jiang Q, Liu X, Ullrich R, George J, Heitzeneder S, Tunuguntla R, Sage J, Sotillo E, Mackall CL, Feldman SA.   +25 more
europepmc   +1 more source

A New Paradigm of Bispecific Antibodies in Clinical Management of Gastrointestinal Cancers. [PDF]

Oncol Res
Zhao H, Wang X, Fan Z, Sun A, Zhang C, Sun C.   +5 more
europepmc   +1 more source

Development of Genetically Modified ARH-77 Feeder Cells for Efficient Expansion of Natural Killer Cells with Potent Anti-Tumor Activity. [PDF]

Cancers (Basel)
Lim YJ, Marr B, Ghaziasgar S, Kim CJ, Baek YJ, Kim GS, Lee JJ, Park YJ, An Y, Lee SH, Kim SK.   +10 more
europepmc   +1 more source

Evolution and recent advances in antibody-drug conjugate therapy for lung cancer: a comprehensive systematic review based on the Trialtrove database (inception to July 1, 2025). [PDF]

Front Oncol
Chen Y, Zhang Y, Tian C, Li Z, Guo G.
europepmc   +1 more source

A molecular and biological study of the role of B7-1 and B7-2 antigens in the immunostimulatory properties of myeloid leukaemic cells

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Genomic organization of the gene coding for the costimulatory human B-lymphocyte antigen B7-2 (CD86)

Immunogenetics, 1995
The generation of an antigen-specific T-cell response requires that the T lymphocyte receive two signals from the antigen presenting cell. The specificity of this response is provided by antigen presented to the T lymphocyte and involves stimulation of the T lymphocyte via the T-cell receptor (TCR)/CD3 complex.
C L, Jellis, S S, Wang, P, Rennert, F, Borriello, A H, Sharpe, N R, Green, G S, Gray   +6 more
openaire   +2 more sources

CD86 (B7-2) Can Function to Drive MHC-Restricted Antigen-Specific CTL Responses In Vivo

The Journal of Immunology, 1999
Abstract Activation of T cells requires both TCR-specific ligation by direct contact with peptide Ag-MHC complexes and coligation of the B7 family of ligands through CD28/CTLA-4 on the T cell surface. We recently reported that coadministration of CD86 cDNA along with DNA encoding HIV-1 Ags i.m.
M G, Agadjanyan, J J, Kim, N, Trivedi, D M, Wilson, B, Monzavi-Karbassi, L D, Morrison, L K, Nottingham, T, Dentchev, A, Tsai, K, Dang, A A, Chalian, M A, Maldonado, W V, Williams, D B, Weiner   +13 more
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Importance of B7-1-Expressing Host Antigen-Presenting Cells for the Eradication of B7-2 Transfected P815 Tumor Cells

The Journal of Immunology, 1998
Abstract We have previously shown that B7-2 (CD86)-transfected P815 tumor cells elicit tumor-eradicating immunity that leads to the regression of the B7-2+ P815 tumor after transient growth in normal DBA/2 mice. Here, we show that both the B7-2 and B7-1 (CD80) molecules contribute to the eradication of B7-2+ P815 tumors as treatment ...
R N, La Motte, A H, Sharpe, J A, Bluestone, M B, Mokyr   +3 more
openaire   +2 more sources

Association of co-stimulatory human B-lymphocyte antigen B7-2 (CD86) gene polymorphism with colorectal cancer risk.

Gastroenterology and hepatology from bed to bench, 2013
This study investigated the role of CD86 +237 G/C polymorphism in intensifying the risk of CRC development.Colorectal cancer (CRC) is a multi-factorial diseases. Genetic background could affect the susceptibility of individuals to CRC development. CD86 is a co-stimulatory factor on antigen-presenting cells that plays key roles in several cancer related
Azimzadeh, Pedram, Romani, Sara, Mirtalebi, Hanieh, Fatemi, Seyed Reza, Kazemian, Shabnam, Khanyaghma, Mahsa, Mohebbi, Seyed Reza   +6 more
openaire   +2 more sources