Synergistic Anticancer Effects of Apatinib and PD-L1 Inhibition in Breast Cancer. [PDF]
Han D, Xu J, Guo C.
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Immunostimulatory and Immunodynamic Modeling Analysis to Determine a Plausible Starting Dose of mRNA-4359 for Use in First-In-Human Trials. [PDF]
Greene SA +7 more
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Advances in protein ubiquitination modification and immune evasion of breast cancer. [PDF]
Wu Y, Jin J, Cheng X, Fu Z, Xie H.
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Research progress on the molecular mechanisms of PD-1 and LAG-3 synergy in regulating T cell exhaustion and immunotherapy. [PDF]
Li M, Duan D, Liu C, Xiong Q.
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Case Report: Unexpected non-pathogenic autoantibodies without clinical involvement following PD-L1 blockade. [PDF]
Zhang L, Jin Z, Wang S.
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Histone lactylation-driven B7-H3 expression promotes tumor immune evasion. [PDF]
Ma Z +9 more
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M2 macrophages predict response to neoadjuvant chemotherapy in triple negative breast cancer patients. [PDF]
Chen WX +7 more
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Pro-Inflammatory Macrophage Phenotype Skewing Induced by Tumor Treating Fields (TTFields). [PDF]
Kan T +9 more
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Stimulation of B7-H1 in Hepatocarcinoma Cells by Hepatitis B virus X Antigen
Immunological Investigations, 2010The cross-talk between the hepatitis B virus X protein (HBx) and B7-H1 in hepatocarcinoma (HCC) is unclear. This study analyzed the potential relationships between HBx and B7-H1 in hepatocarcinogenesis. One of human HCC cell lines, HepG2 cells, was transfected to stably express HBx protein (HBx(+)-HepG2).
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Abstract Impaired CD8+ T cells have been implicated to play a role in the establishment of HCV persistent infection. HCV has evolved multiple strategies to avoid T cell responses. HCV core protein has been shown to contain immunomodulatory functions.
John R Lukens, Young S Hahn
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