Results 61 to 70 of about 545,026 (158)
Immunology, Volume 177, Issue 4, Page 752-765, April 2026.Our data show that suppressing IRF2, genetically or by siRNA, modulates PD‐L1 and MHC‐I levels. This induced immune‐evasive state critically underlies the significantly prolonged survival of cardiac allografts, revealing a novel therapeutic avenue.
Li Tian +5 more
wiley +1 more source
Detrimental contribution of the immuno-inhibitor b7-h1 to rabies virus encephalitis. [PDF]
, 2008 International audienceRabies virus is the etiological agent of an acute encephalitis, which in absence of post exposure treatment is fatal in almost all cases. Virus lethality rests on its ability to evade the immune response.
Prehaud, Prehaud +14 more
core +1 more source
Clinical significance and regulation of the costimulatory molecule B7-H1 in pancreatic cancer.
, 2008 We investigated the expression pattern and clinical significance of the costimulatory ligands B7-1, B7-2, B7-H1, and B7-DC, and their counter-receptors CTLA-4 and PD-1 in pancreatic cancer.
Loos, M;Giese, NA;Kleeff, J;Giese, T;Gaida, MM;Bergmann, F;Laschinger, M;W Büchler, M;Friess, H
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B7-H1–Dependent Sex-Related Differences in Tumor Immunity and Immunotherapy Responses
, 2010 CD4+CD25+Foxp3+ regulatory T cells (Tregs) are immunopathogenic in cancers by impeding tumor-specific immunity. B7-homologue 1 (B7-H1) (CD274) is a cosignaling molecule with pleiotropic effects, including hindering antitumor immunity.
Ratna K. Vadlamudi +13 more
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Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
B7-H1(PD-L1) confers chemoresistance through ERK and p38 MAPK pathway in tumor cells
, 2018 Development of resistance to chemotherapy and immunotherapy is a major obstacle in extending the survival of patients with cancer. Although several molecular mechanisms have been identified that can contribute to chemoresistance, the role of immune ...
Chunhua Chen +13 more
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Kinetics and dose response of PG mediated B7-H1 upregulation.
, 2015 (A) Flow cytometry was done to measure B7-H1 expression on AGS cells after treating the cells with different concentrations (1 μg/ml, 10 μg/ml and 100 μg/ml) of iEDAP for 24-h.
Jennifer House (711490) +7 more
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, 2003 Human glioblastoma is a highly lethal tumor that is known for its immune inhibitory capabilities. B7-homologue 1 (B7-H1), a recently identified homologue of B7.1/2 (CD80/86), has been described to exert costimulatory and immune regulatory functions.
Chen, L +7 more
core +1 more source
Resting respiratory tract dendritic cells preferentially stimulate T helper cell Type 2(Th2) responses and require obligatory cytokine signals for induction of Th1 immunity [PDF]
, 1998 Consistent with their role in host defense, mature dendritic cells (DCs) from central lymphoid organs preferentially prime for T helper cell type 1 (Th1)-polarized immunity.
Venaille, T.J. +6 more
core
HDAC is indispensable for IFN-γ-induced B7-H1 expression in gastric cancer
, 2018 Background B7 homolog 1 (B7-H1) overexpression on tumor cells is an important mechanism of immune evasion in gastric cancer (GC). Elucidation of the regulation of B7-H1 expression is urgently required to guide B7-H1-targeted cancer therapy.
Kaixiong Tao +11 more
core +1 more source