Results 111 to 120 of about 12,335 (206)

Anterior Pituitary Progenitor Cells Express Costimulatory Molecule 4Ig-B7-H31 [PDF]

open access: yes, 2008
Stem/Progenitor cells in the postnatal pituitary gland are embedded in a marginal cell layer around Rathke’s pouch. However, the nature and behavior of anterior pituitary progenitor cells remain unclear.
Aso, Hisashi   +9 more
core   +2 more sources

Open Innovation for Circular Business Models: Addressing the Right Challenge at the Right Time

open access: yesJournal of Product Innovation Management, EarlyView.
ABSTRACT Academic Summary In response to escalating societal challenges, such as climate change and resource constraints, this article examines the transition from linear toward circular business models (CBMs). It explores the challenges of CBM transitions and how to tackle them through open innovation.
Daniel Wörner   +4 more
wiley   +1 more source

Immune checkpoint B7-H3 is a potential therapeutic target in prostate cancer

open access: yesDiscover Oncology
High expression of immune checkpoint molecule B7-H3 (CD276) in many cancer types makes it a promising immunotherapeutic target. Both coinhibitory and costimulatory effects of B7-H3 in tumors have been demonstrated, but the mechanism of B7-H3 immune ...
Qi Shen   +7 more
doaj   +1 more source

B7-H3/CD276 and small-cell lung cancer: What's new? [PDF]

open access: yes
Immunotherapy revolutionized the treatment landscape of several cancers, including small-cell lung cancer (SCLC), with a huge number of practice-changing trials, and becoming a new frontier for their management.
Fabrizio FP, Muscarella LA, Rossi A
core   +1 more source

Increased concentrations of soluble B7-H3 and interleukin 36 in bronchoalveolar lavage fluid of Children with Mycoplasma pneumoniae pneumonia [PDF]

open access: yes, 2016
Supporting data.
Canhong Zhu   +9 more
core   +2 more sources

Mendelian randomization analysis identifies HLA‐A and AP2M1 as genetic biomarkers linked to immune–endocytic crosstalk in intervertebral disc degeneration

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 1, March 2026.
HLA‐A and AP2M1 are identified as key endocytosis‐related biomarkers that modulate immune–endocytic crosstalk via mTOR signaling to regulate cell survival, immune infiltration, and the progression of intervertebral disc degeneration. Abstract Intervertebral disc degeneration (IVDD) is a major contributor to chronic spinal disorders, yet the role of ...
Yukui Tian   +4 more
wiley   +1 more source

A promising target for breast cancer: B7-H3

open access: yesBMC Cancer
AbstractBreast cancer (BC) is the second-leading factor of mortality for women globally and is brought on by a variety of genetic and environmental causes. The conventional treatments for this disease have limitations, making it difficult to improve the lifespan of breast cancer patients. As a result, extensive research has been conducted over the past
Ying Jiang   +4 more
openaire   +3 more sources

High expression of B7-H3 on monocyte/macrophages in tumor microenvironment promotes lung cancer progression by inhibiting apoptosis

open access: yesTranslational Oncology
Monocyte/macrophages constitute a significant population of tumor-infiltrating immune cells and play a crucial role in tumor growth, invasion, and metastasis.
Dongze Zhang   +8 more
doaj   +1 more source

Cellular interactions in the tumor microenvironment: the role of secretome [PDF]

open access: yes, 2019
Over the past years, it has become evident that cancer initiation and progression depends on several components of the tumor microenvironment, including inflammatory and immune cells, fibroblasts, endothelial cells, adipocytes, and extracellular matrix ...
Castelo-Branco, Pedro   +6 more
core   +1 more source

Turning Everything Upside Down: The Impact of Illness on Romantic Relationships—A SEM‐Based Actor‐Partner Interdependence Model

open access: yesFamily Process, Volume 65, Issue 1, March 2026.
ABSTRACT Illnesses are often associated with fundamental changes in relationship dynamics. Yet, little is known about how different acute and chronic conditions distinctly impact both partners' well‐being. This study analyzed the reciprocal associations between different illnesses on life satisfaction and relationship satisfaction in partnerships ...
Franziska Reinhardt, Imad Maatouk
wiley   +1 more source

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