Results 61 to 70 of about 31,066,857 (388)
Transplantation, 2006 Autoreactive B cells are actively tolerized to more abundant self-antigens by a series of checkpoints involving receptor editing, deletion, anergy and competition for growth factors. In contrast, B cells reactive against rare, sequestered or tissue specific self-antigens remain functionally naïve.
Ferry, H +6 more
openaire +3 more sources
The B cell receptor, but not the pre-B cell receptor, mediates arrest of B cell differentiation [PDF]
European Journal of Immunology, 2000 B cell development in organ cultures of fetal liver from mice at day 14 of gestation resembles in kinetics and cell numbers generated the one observed in vivo. This development in vitro can be blocked by an IL-7 receptor-specific monoclonal antibody. Monoclonal antibodies specific for the pre-B cell receptor, i. e. for VpreB, lambda5, or muH chains, do
Antonius Rolink +3 more
openaire +3 more sources
B cell memory: building two walls of protection against pathogens
Nature reviews. Immunology, 2019 Surviving a single infection often results in lifelong immunity to the infecting pathogen. Such protection is mediated, in large part, by two main B cell memory ‘walls’ — namely, long-lived plasma cells and memory B cells.
M. Akkaya, Kihyuck Kwak, S. Pierce
semanticscholar +1 more source
Association of B-cell Lymphoma Protein-2 and Caspase-3 Expression in Ovarian Cancer [PDF]
, 2013 Ovarian cancer remains a major problem of women's health in the world, including Indonesia, and is associated with high rates of incidence and mortality. There are many efforts in early diagnosis on ovarian cancer, but until now there have not been found
Budiana, I. N. (I)
core
Conjugate Haemophilus influenzae type b vaccines for sickle cell disease. [PDF]
, 2016 BACKGROUND: People affected with sickle cell disease are at high risk of infection from Haemophilus influenzae type b. Before the implementation of Haemophilus influenzae type b conjugate vaccination in high-income countries, this was responsible for a ...
Allali, Slimane +4 more
core +2 more sources
occumb: An R package for site occupancy modeling of eDNA metabarcoding data
Population Ecology, EarlyView.This study introduces a new R package, occumb, for the convenient application of site occupancy modeling using environmental DNA (eDNA) metabarcoding data. We outline a data analysis workflow, including data setup, model fitting, model assessment, and comparison of potential study settings based on model predictions, all of which can be performed using
Keiichi Fukaya, Yuta Hasebe
wiley +1 more source
Iraqi Journal of HematologyBACKGROUND: B-cells express a variety of clusters of differentiation markers during development. These markers determine the basic function of the immune phenotype specific to B-cells.
Rahab Abd-Ali Al-Madany +1 more
doaj +1 more source
EMBO Molecular Medicine, 2015 Activation‐induced deaminase (AID) initiates secondary antibody diversification in germinal center B cells, giving rise to higher affinity antibodies through somatic hypermutation (SHM) or to isotype‐switched antibodies through class switch recombination
Arantxa Pérez‐García +7 more
doaj +1 more source
Molecular and functional properties of human Plasmodium falciparum CSP C‐terminus antibodies
EMBO Molecular Medicine, 2023 Human monoclonal antibodies (mAbs) against the central repeat and junction domain of Plasmodium falciparum circumsporozoite protein (PfCSP) have been studied extensively to guide malaria vaccine design compared to antibodies against the PfCSP C terminus.
Opeyemi Ernest Oludada +12 more
doaj +1 more source
Primary mediastinal lymphoma: diagnosis and treatment options. [PDF]
, 2014 Primary mediastinal large B-cell lymphoma (PMBCL) is a unique B-cell lymphoma variant that arises from a putative thymic medulla B cell. It constitutes 2-4% of non-Hodgkin lymphomas and occurs most frequently in young females. PMBCL is characterized by a
DI ROCCO, Alice +4 more
core +1 more source