Results 71 to 80 of about 21,583,992 (313)
Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari +5 more
wiley +1 more source
Towards Understanding KSHV Fusion and Entry
Viruses, 2019 How viruses enter cells is of critical importance to pathogenesis in the host and for treatment strategies. Over the last several years, the herpesvirus field has made numerous and thoroughly fascinating discoveries about the entry of alpha-, beta-, and ...
Stephen J. Dollery
doaj +1 more source
Proceedings of the National Academy of Sciences, 2000 Interest is reviving in the role of antibodies in autoimmunity. Over the last two decades, T cells occupied center stage for several reasons: They predominate within tissues undergoing autoimmune attack, they can transfer autoimmune disease in animal models, and diseases such as rheumatoid arthritis and insulin-dependent diabetes mellitus associate ...
N A, Mitchison, L R, Wedderburn
openaire +3 more sources
B cells and atherosclerosis [PDF]
American Journal of Physiology-Heart and Circulatory Physiology, 2017 B cells have emerged as important immune cells in cardiovascular disease. Initial studies have suggested that B cells protect against atherosclerosis development. However, subsequent studies demonstrating aggravation of atherosclerosis by B-2 cells have shed light on the subset-dependent effects of B cells.
Prasad, Srikakulapu, Coleen A, McNamara
openaire +2 more sources
Lineage-specific genes are prominent DNA damage hotspots during leukemic transformation of B-cell precursors [PDF]
, 2017 In human leukemia, lineage - specific genes represent predominant targets of deletion, with lymphoid - specific genes frequently affected in lymphoid leukemia and myeloid - specific genes in myeloid leukemia.
Mark E. Robinson +32 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman +9 more
wiley +1 more source
Scientific Reports, 2019 One of the central goals of today’s neuroscience is to achieve the conceivably most accurate classification of neuron types in the mammalian brain. As part of this research effort, electrophysiologists commonly utilize current clamp techniques to gain a ...
Ferenc Hernáth +2 more
doaj +1 more source
Autoimmunity, 2020 High mobility group box 1 (HMGB1) played pathogenic role in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). Recent findings demonstrated that Toll-like receptor 9 (TLR9) was involved in B cell tolerance breaking of autoimmune ...
Chen Wang +5 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad +9 more
wiley +1 more source