Results 41 to 50 of about 5,027,866 (266)

Advancements in understanding the regulatory mechanism of B-cell immune activation associated with adenotonsillar hypertrophy

open access: yes生物医学转化
B cells play a crucial role in recognizing external antigens through their surface B cell receptor (BCR), essential for generating protective antibodies and immune memory.
Chen Wenjing   +4 more
doaj   +1 more source

Purification, characterization, and expression of rat intestinal alkaline sphingomyelinase

open access: yesJournal of Lipid Research, 2002
Intestinal alkaline sphingomyelinase (SMase) has physiological roles in the digestion of sphingomyelin (SM) and clinical implications in colonic carcinogenesis.
Yajun Cheng   +3 more
doaj   +1 more source

Molecular and functional properties of human Plasmodium falciparum CSP C‐terminus antibodies

open access: yesEMBO Molecular Medicine, 2023
Human monoclonal antibodies (mAbs) against the central repeat and junction domain of Plasmodium falciparum circumsporozoite protein (PfCSP) have been studied extensively to guide malaria vaccine design compared to antibodies against the PfCSP C terminus.
Opeyemi Ernest Oludada   +12 more
doaj   +1 more source

Assay Development for Phagocytosis Activity Evaluation

open access: yesBiology and Life Sciences Forum, 2023
The efficiency of phagocytic activity is a significant organism indicator which decreases with the aging of the immune system. Medications are able to influence phagocytosis, having a blocking or activating effect, and therefore are important modulators ...
Elena Lysakova   +4 more
doaj   +1 more source

The B cell antigen receptor in B-cell development

open access: yesCurrent Opinion in Immunology, 1994
During B-cell development, immature and mature forms of the B cell antigen receptor complex are deployed in a regulated fashion; thus, B cell antigen receptor complexes play essential roles in the transit of cells through ontogeny. The past year has seen progress in our understanding of how antigen receptor gene assembly is controlled and in defining ...
openaire   +2 more sources

Rational Use of Herbal Products in Pediatric Patients Treated With Anticancer Drugs in the European Union

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot   +6 more
wiley   +1 more source

CD19 and POU2AF1 are Potential Immune-Related Biomarkers Involved in the Emphysema of COPD: On Multiple Microarray Analysis

open access: yesJournal of Inflammation Research, 2022
Da-Wei Zhang,1,2,* Jing-Jing Ye,1,2,* Ying Sun,1,2 Shuang Ji,1,2 Jia-Ying Kang,1,2 Yuan-Yuan Wei,1,2 Guang-He Fei1,2 1Department of Respiratory and Critical Care Medicine, First Affiliated Hospital of Anhui Medical University, Hefei, 230022 ...
Zhang DW   +6 more
doaj  

Improved Early Referral in Long‐Term Survivor Care With Institutional Standardized Practice Among Childhood Leukemia Survivors#

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT In 2018, the Texas Children's Cancer and Hematology Center Leukemia Program implemented a practice standard to support the transition from treatment to survivorship that includes shared, alternating care between leukemia and survivorship clinicians and a reminder to refer survivors to the long‐term survivor clinic (LTSC) 2 years after ...
Ji Yun Tark   +9 more
wiley   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall   +2 more
wiley   +1 more source

Interferon regulatory factor 1 enhances T cell differentiation in patients with myasthenia gravis

open access: yesNeural Regeneration Research
Interferon regulatory factor 1 is involved in many autoimmune conditions and is increased in patients with myasthenia gravis. However, its function in myasthenia gravis remains unclear.
Yuebei Luo   +5 more
doaj   +1 more source

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