Results 31 to 40 of about 9,437,655 (307)
Opposing roles of B lymphocyte subsets in atherosclerosis
Autoimmunity, 2017 Atherosclerosis is initiated by cholesterol entry into arteries that triggers chronic immune-inflammatory lesions in the vessels. Early lesions are clinically insignificant but advanced complex lesions and vulnerable rupture prone lesions impact on ...
Tin Kyaw +3 more
doaj +1 more source
B cells and atherosclerosis [PDF]
American Journal of Physiology-Heart and Circulatory Physiology, 2017 B cells have emerged as important immune cells in cardiovascular disease. Initial studies have suggested that B cells protect against atherosclerosis development. However, subsequent studies demonstrating aggravation of atherosclerosis by B-2 cells have shed light on the subset-dependent effects of B cells.
Prasad, Srikakulapu, Coleen A, McNamara
openaire +2 more sources
Sequential induction of NF-κB/Rel family proteins during B-cell terminal differentiation [PDF]
, 1994 The NF-kappa B/Rel family of at least five transcription factor polypeptides is thought to function both as a developmental regulator in B cells and as a rapid response system in all cells. To examine this notion in more detail, we determined the protein
Baltimore, David +3 more
core +1 more source
IgM and IgD B cell receptors differentially respond to endogenous antigens and control B cell fate. [PDF]
, 2018 Naive B cells co-express two BCR isotypes, IgM and IgD, with identical antigen-binding domains but distinct constant regions. IgM but not IgD is downregulated on autoreactive B cells. Because these isotypes are presumed to be redundant, it is unknown how
Brombacher, Frank +5 more
core +3 more sources
Stem Cells International, 2019 Impaired wound healing and tissue regeneration have severe consequences on the patient’s quality of life. Micrograft therapies are emerging as promising and affordable alternatives to improve skin regeneration by enhancing the endogenous wound repair ...
Martina Balli +6 more
doaj +1 more source
SDF-1 and PDGF enhance [alpha]v[beta]5-mediated ERK activation and adhesion-independent growth of human pre-B cell lines [PDF]
, 2009 CD23 acts through the [alpha]v[beta]5 integrin to promote growth of human pre-B cell lines in an adhesion-independent manner. [alpha]v[beta]5 is expressed on normal B-cell precursors in the bone marrow.
Acharya, M. +3 more
core +2 more sources
Conjugate Haemophilus influenzae type b vaccines for sickle cell disease. [PDF]
, 2016 BACKGROUND: People affected with sickle cell disease are at high risk of infection from Haemophilus influenzae type b. Before the implementation of Haemophilus influenzae type b conjugate vaccination in high-income countries, this was responsible for a ...
Allali, Slimane +4 more
core +2 more sources
Iraqi Journal of HematologyBACKGROUND: B-cells express a variety of clusters of differentiation markers during development. These markers determine the basic function of the immune phenotype specific to B-cells.
Rahab Abd-Ali Al-Madany +1 more
doaj +1 more source
Acute disruption of bone marrow B lymphopoiesis and apoptosis of transitional and marginal zone B cells in the spleen following a blood-stage Plasmodium chabaudi infection in mice [PDF]
, 2011 B cells and antibodies are essential for the protective immune response against a blood-stagePlasmodiuminfection. Although extensive research has focused on memory as well as plasma B-cell responses during infection, little is known about how malaria ...
Bockstal, Viki +2 more
core +2 more sources
Kidney DiseasesIntroduction: The increasing incidence of diabetic kidney disease (DKD) and the challenges in its management highlight the necessity for a deeper understanding of its pathogenesis.
Yuan Ma +7 more
doaj +1 more source