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CD4-helper-independent antiviral function of CD8-positive memory T lymphocytes derived from latently infected donors [PDF]
The ability of memory T lymphocytes derived from latently infected mice to control murine cytomegalovirus disease in the immunocompromised host was studied by adoptive transfer experiments.
Reddehase, Matthias J. +4 more
core +1 more source
Conditional immortalization of human B cells by CD40 ligation [PDF]
It is generally assumed that human differentiated cells have a limited life-span and proliferation capacity in vivo, and that genetic modifications are a prerequisite for their immortalization in vitro.
Mayr, C. +27 more
core +1 more source
CD5-Positive B Lymphocytes after Kidney Transplantation
Kidney transplantation is the treatment of choice for end-stage kidney diseases. Unfortunately, kidney allograft recipients rarely develop tolerance or accommodation and require life-long immunosuppression.
Maciej Zieliński +9 more
doaj +1 more source
Background The objective was to evaluate concordance between 2002 American-European Consensus Group (AECG) and 2016 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) classification criteria for primary Sjögren’s syndrome ...
Maëlle Le Goff +13 more
doaj +1 more source
Recent studies have revealed that B cells play a critical role in autoimmunity and disease expression through various functions, including autoantibody production, cytokine secretion, antigen presentation, and co-stimulatory effect. Selective targeting of B cells has been recently achieved using a chimeric monoclonal antibody against CD20 (Rituximab ...
openaire +3 more sources
Morphologic observations of human T and B lymphocytes by scanning electron microscopy
T cell concerned with cell mediated immunity and B cell concerned with humoral antibody are classified by scanning electron microscopy of the surface structure of lymphocytes using E binding lymphocytes and EAC (sensitized sheep erythrocytes treated with
Yamamoto, Isamu
core +1 more source
SummaryA major proportion of CD5+ B lymphocytes are committed to the production of a discrete type of antibody that is polyreactive. Polyreactive antibodies appear to use selected V and, perhaps, D gene segments, mostly in unmutated configuration. They generally display relatively low affinity for different antigens and are often part of the primary ...
M T, Kasaian, H, Ikematsu, P, Casali
openaire +2 more sources
Coupling imaging mass cytometry with Alcian blue histochemical staining for a single-slide approach
Imaging mass cytometry (IMC) is a metal mass spectrometry-based method allowing highly multiplex immunophenotyping of cells within tissue samples. However, some limitations of IMC are its 1-µm resolution and its time and costs of analysis limiting ...
Patrice Hemon +11 more
doaj +1 more source
RITUXIMAB TREATMENT FOR INTERSTITIAL LUNG INJURY IN SCLERODERMA SYSTEMATICA
Objective: to study the efficiency and tolerance of rituximab (RTM) treatment in patients with scleroderma systematica (SDS) with interstitial lung injury (ILI).Subjects and methods. The trial included 27 patients (26 women and 1 man) (mean age 45.7±13.0
Lidia Petrovna Ananieva +10 more
doaj +1 more source
B-lymphocytes as key players in chemical-induced asthma. [PDF]
T-lymphocytes and B-lymphocytes are key players in allergic asthma, with B-lymphocytes producing antigen-specific immunoglobulins E (IgE). We used a mouse model of chemical-induced asthma and transferred B-lymphocytes from sensitized animals into naïve ...
Vanessa De Vooght +7 more
doaj +1 more source

