Results 1 to 10 of about 14,694,625 (350)

CD19 and CD20 targeted vectors induce minimal activation of resting B lymphocytes. [PDF]

open access: yesPLoS ONE, 2013
B lymphocytes are an important cell population of the immune system. However, until recently it was not possible to transduce resting B lymphocytes with retro- or lentiviral vectors, making them unsusceptible for genetic manipulations by these vectors ...
Sabrina Kneissl   +5 more
doaj   +16 more sources

Advances in tumor-infiltrating B lymphocytes [PDF]

open access: yesCentral European Journal of Immunology
In the landscape of tumor immunotherapy, T cell-mediated immune responses have consistently captured the attention, while the contributions of B cells have been neglected.
Yule Zhang   +4 more
doaj   +2 more sources

The Prognostic Importance of CD20+ B lymphocytes in Colorectal Cancer and the Relation to Other Immune Cell subsets

open access: yesScientific Reports, 2019
The anti-tumour immune response is critical to patient prognosis in colorectal cancer (CRC). The aim of this study was to investigate infiltration of B lymphocytes into CRC tumours, and their clinical relevance, prognostic value and relation to other ...
Sofia Edin   +9 more
doaj   +2 more sources

The Inflammatory Contribution of B-Lymphocytes and Neutrophils in Progression to Osteoporosis [PDF]

open access: yesCells, 2023
Osteoporosis is a bone disease characterized by structural deterioration and low bone mass, leading to fractures and significant health complications. In this review, we summarize the mechanisms by which B-lymphocytes and neutrophils contribute to the ...
Drew Frase   +4 more
doaj   +2 more sources

Aberrations in peripheral B lymphocytes and B lymphocyte subsets levels in Parkinson disease: a systematic review [PDF]

open access: yesFrontiers in Immunology
ObjectiveThe association of B lymphocytes and B lymphocyte subsets and Parkinson’s disease (PD) is increasingly acknowledged. However, there is inconsistence in the alterations of B lymphocytes or B lymphocyte subsets in peripheral blood of PD patients ...
Hongxia Ma   +5 more
doaj   +2 more sources

Application of High-Throughput Imaging Mass Cytometry Hyperion in Cancer Research

open access: yesFrontiers in Immunology, 2022
Imaging mass cytometry (IMC) enables the in situ analysis of in-depth-phenotyped cells in their native microenvironment within the preserved architecture of a single tissue section.
Marion Le Rochais   +5 more
doaj   +1 more source

Deciphering the maturation of tertiary lymphoid structures in cancer and inflammatory diseases of the digestive tract using imaging mass cytometry

open access: yesFrontiers in Immunology, 2023
Persistent inflammation can promote the development of tertiary lymphoid structures (TLS) within tissues resembling secondary lymphoid organs (SLO) such as lymph nodes (LN).
Marion Le Rochais   +10 more
doaj   +1 more source

Could AMPs and B-cells be the missing link in understanding periodontitis?

open access: yesFrontiers in Immunology, 2022
Periodontal diseases are common inflammatory conditions characterized by bone loss in response to simultaneous bacterial aggression and host defenses. The etiology of such diseases is still not completely understood, however.
Vanessa Dominique Lobognon   +2 more
doaj   +1 more source

IL-7-Adjuvanted Vaginal Vaccine Elicits Strong Mucosal Immune Responses in Non-Human Primates

open access: yesFrontiers in Immunology, 2021
Mucosal immune responses are crucial in protecting against pathogens entering through mucosal surfaces. However, due to poor T-cell responsiveness upon mucosal antigenic stimulation, mucosal immunity remains difficult to obtain through vaccines and ...
Sandrine Logerot   +9 more
doaj   +1 more source

Discrimination of human cytotoxic lymphocytes from regulatory and B-lymphocytes by orthogonal light scattering [PDF]

open access: yes, 1986
Light scattering properties of human lymphocyte subpopulations selected by immunofluorescence were studied with a flow cytometer. Regulatory and B-lymphocytes showed a low orthogonal light scatter signal, whereas cytotoxic lymphocytes identified with leu-
Berkel, W. van   +4 more
core   +9 more sources

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