Results 101 to 110 of about 216,975 (333)

Examining the basis of isoniazid tolerance in nonreplicating Mycobacterium tuberculosis using transcriptional profiling [PDF]

, 2010
Background: Understanding how growth state influences Mycobacterium tuberculosis responses to antibiotic exposure provides a window into drug action during patient chemotherapy.
Cunningham, Denis A Mitchison, Griselda Tudó, Ken Laing, Miesel, Philip D Butcher, Simon J Waddell, Wayne, Zhang   +8 more
core   +2 more sources

Beginning on bacilli [PDF]

Nature, 1983
Bacillus subtilis. The Molecular Biology of the Bacilli, Vol. 1. Edited by David A. Dubnau. Academic: 1982. $44, £29.20.
openaire   +1 more source

Self‐Adjusting Engineered Probiotic for Targeted Tumor Colonization and Local Therapeutics Delivery

Advanced Science, EarlyView.
Zou et al. developed an engineered strain of Escherichia coli Nissle 1917 with precise targeting abilities for colonization and on‐demand payload release. The engineered probiotic survives and embolizes tumors only in the presence of more than 5 mM L‐lactate. Furthermore, the introduction of an α‐hemolysin circuit enhances its anti‐tumor effect.
Zhen‐Ping Zou, Xin‐Ge Wang, Xuan‐Ren Shi, Shu‐Ting Sun, Jing Mi, Xiao‐Peng Zhang, Bin‐Cheng Yin, Ying Zhou, Bang‐Ce Ye   +8 more
wiley   +1 more source

In vitro Effects of Two Silver Electrodes on Select Wound Pathogens [PDF]

, 1995
The use of electrical current to promote wound healing is well documented. However, little is understood about the effects of micro-amperage direct current (μADC) on growth of wound pathogens.
Kloth, Luther C., Laatsch-Lybeck, Linda Jean, Ong, Poh Chye   +2 more
core   +1 more source

Colonic Submucosa Targeted Delivery of Probiotic and Rhein for Ulcerative Colitis Treatment

Advanced Science, EarlyView.
A novel orally drug‐probiotic co‐delivery system designated as Rh‐YBS for UC treatment, which highlights three innovations: (i) YPs involves colonic submucosa delivery via M cells; (ii) Rh (drug) promotes the colonization and growth of BS (probiotic) in the colon.
Lingqiang Li, Linxin Dai, Meisi Lin, Shuang He, Hongye Du, Dasheng Lin, Yanbin Wang, Fenglian Zhang, Sian Tao, Xiaoluo Sun, Xinggui Huang, Haihui Liu, Qian Wang, Lingling He, Kunhe Wu, Jieshu You, Minyue Zhang, Chaomei Fu, He Tu, Naijing Ye, Jibin Liu, Fei Gao   +21 more
wiley   +1 more source

The bactericidal activity of moxifloxacin in patients with pulmonary tuberculosis [PDF]

, 2003
Patients in whom acid-fast bacilli smear-positive pulmonary tuberculosis was newly diagnosed were randomized to receive 400 mg moxifloxacin, 300 mg isonaizid, or 600 mg rifampin daily for 5 days. Sixteen-hour overnight sputa collections were made for the
Bongard, E, Gillespie, SH, Gosling, RD, Kanduma, EG, Morris, RW, Nyindo, M, Sam, NE, Uiso, LO   +7 more
core   +1 more source

Microneedles at the Forefront of Next Generation Theranostics

Advanced Science, EarlyView.
The TOC figure illustrates the revolutionary role of microneedles in modern medicine, showcasing their dual diagnostic and therapeutic functions. On the left, microneedles access interstitial fluid for real‐time monitoring of biomarkers like glucose and hormones.
Chan Wang, Yuan Yang, Jiaqi Zhang, Hanrui Zhang, Qian Wang, Shengmei Ma, Pengfei Zhao, Zhou Li, Yuxin Liu   +8 more
wiley   +1 more source

The detection of airborne transmission of tuberculosis from HIV-infected patients, using an in vivo air sampling model [PDF]

, 2007
Background. Nosocomial transmission of tuberculosis remains an important public health problem. We created an in vivo air sampling model to study airborne transmission of tuberculosis from patients coinfected with human immunodeficiency virus (HIV) and ...
A. Gonzalez, A. R. Escombe, Balasubramanian, Beggs, Bhatia, C. A. Evans, C. Martinez, C. Noakes, C. Oeser, Caviedes, Cohn, Curtis, D. A. J. Moore, E. Ticona, Edlin, Elliott, Escombe, Gangadharam, Ikeda, J. S. Friedland, Katz, L. Caviedes, Luna-Herrera, M. Navincopa, Markowitz, Mastorides, Mills, Mitchison, Mitchison, Nardell, Nardell, Nunn, P. Sheen, Prabhakar, R. H. Gilman, Riley, RILEY, Riley, Schafer, Sultan, Xu   +40 more
core   +2 more sources

Elastic Deformation of Cellulose/Lignin‐Based Anode for Rejuvenating Aged Mix‐Cultured Electroactive Biofilms

Advanced Science, EarlyView.
A new strategy for revitalizing aged biofilms using the elastic deformation of biomass‐based flexible carbon aerogel is proposed. The elastic deformation removes the nonelectrogenic bacteria and the dead electrogenic bacteria, as well as a lot of loosely bound extracellular polymer materials.
Xue Liu, Zheng Zhang, Qingwen Zheng, Chengcheng Suo, Bailing Dong, Huiying Song, Jiayi Wang, Jia Liu, Runfeng Yuan, Sailike Milanbieke, Sha Luo, Chenhui Yang, Zhijun Chen, Ruiwen Wang, Wei Li, Shouxin Liu   +15 more
wiley   +1 more source

KK2DP7 Stimulates CD11b+ Cell Populations in the Spleen to Elicit Trained Immunity for Anti‐Tumor Therapy

Advanced Science, EarlyView.
This study introduces KK2DP7, a dendrimer‐structured peptide adjuvant, as a tool to decode trained immunity's role in antitumor therapy. Splenic CD11b+ cells mediate tumor suppression via TLR2‐IRF7 activation and epigenetic reprogramming, validated by adoptive transfer experiments.
Rui Zhang, Lin Tang, Yusi Wang, Xuejing Zhou, Zhenyu Ding, Li Yang   +5 more
wiley   +1 more source