Antitubercular specific activity of ibuprofen and the other 2-arylpropanoic acids using the HT-SPOTi whole-cell phenotypic assay [PDF]
, 2013 Objectives: Lead antituberculosis (anti-TB) molecules with novel mechanisms of action are urgently required to fuel the anti-TB drug discovery pipeline.
Bhakta, Sanjib +9 more
core +1 more source
The Atypical Dysentery Bacilli [PDF]
Journal of Hygiene, 1919 As there appears to be a considerable amount of uncertainty (as evidenced by recent writings on this subject) regarding the biological relationships and the etiological significance of the so-called “atypical B. dysenteriae,” this short communication is intended as a brief résumé of conclusions arrived at in the course of an extended investigation of ...
openaire +3 more sources
Identification and Application of a Novel Patulin Degrading Enzyme From Meyerozyma guilliermondii
Advanced Science, EarlyView.Patulin (PAT), a hazardous mycotoxin, threatens human health. A novel yeast‐derived short‐chain dehydrogenase/reductase effectively degrades PAT into nontoxic ascladiol via catalytic triad activity. The biological detoxification process has no significant effect on the quality of fresh pear juice.
Yu Zhang +7 more
wiley +1 more source
Effects of Silver Nanoparticles on Urinary Tract Infections Caused by Gram-negative Bacilli Resistant to Several Antibiotics (MDR) [PDF]
بیولوژی کاربردی, 2017 One of the major problems in hospitals resistance of pathogenic bacteria , including bacteria that cause urinary tract infections(UTI), antimicrobial substances , the problem of increased costs of treatment , treatment failure and mortality rates are ...
نشاط غلامی +2 more
doaj
FURTHER OBSERVATIONS CONCERNING GROWTH REQUIREMENTS OF HEMOPHILIC BACILLI [PDF]
, 1927 Francis C. O. Valentine +1 more
openalex +1 more source
Advanced Science, EarlyView.Gasdermin D (GSDMD) does not only reduce pancreatic enzyme synthesis but also induces pancreatic acinar cells to express mucin 1 (MUC1), which forms a barrier to prevent digestive enzyme‐mediated digestion. However, GSDMD can promote the secretion of inflammatory cytokines by macrophages and aggravate pancreatic histological injury by expanding ...
Chaoxu Liu +10 more
wiley +1 more source
Specific immunoassays confirm association of Mycobacterium avium subsp. paratuberculosis with type-1 but not type-2 diabetes mellitus [PDF]
, 2009 Background Mycobacterium avium subspecies paratuberculosis (MAP) is a versatile pathogen with a broad host range. Its association with type-1 diabetes mellitus (T1DM) has been recently proposed.
Ahmed, Niyaz +7 more
core
A Method of Preserving Typhoid Stools for Delayed Examination and a Comparative Study of the Efficacy of Eosin Brilliant-Green Agar, Eosin Methylene-Blue Agar, and Endo Agar for the Isolation of Typhoid Bacilli from Stools [PDF]
, 1916 Oscar Teague, A. W. Clurman
openalex +1 more source
Advanced Science, EarlyView.KRAS mutations dynamically remodel the tumor microenvironment (TME), fostering immunosuppression, metabolic symbiosis, and stromal plasticity. This review dissects how oncogenic KRAS variants sculpt TME networks and explores actionable vulnerabilities. Emerging strategies combining KRAS inhibitors and TME‐editing approaches offer potential to dismantle
Jiayao Ma +9 more
wiley +1 more source
Enhancing Cold Adaptation of Bidomain Amylases by High‐Throughput Computational Engineering
Angewandte Chemie, EarlyView.This work uncovers molecular determinants of cold adaptation in bidomain amylases by combining MD simulations and biochemical assays, revealing that increased domain separation drives enhanced activity at low temperatures. Guided by this principle, high‐throughput in silico linker screening of mesophilic psA was performed, yielding variant psA121 with ...
Ning Ding +6 more
wiley +2 more sources