Results 201 to 210 of about 216,975 (333)

Diversity of ThDP‐Dependent Enzymes Forming Chiral Tertiary Alcohols

open access: yesChemBioChem, EarlyView.
Chiral tertiary alcohols are widespread in nature and bioactive compounds; however, their asymmetric synthesis faces several challenges. This review outlines the toolbox of ThDP‐dependent enzymes able to produce tertiary alcohols through the formation of CC bond formation using ketones as acceptor substrates. Herein, the substrate scope, the diversity
Daniela Bjarnesen   +4 more
wiley   +1 more source

Unprecedented in vivo activity of telacebec against Mycobacterium leprae. [PDF]

open access: yesPLoS Negl Trop Dis
Chauffour A   +4 more
europepmc   +1 more source

Mammalian Tolerance to Amino Acid Heterochirality

open access: yesChemBioChem, Accepted Article.
Organisms use amino acids predominantly in l‐configuration. On the other hand, a series of studies show that a variety of d‐amino acids also occur in mammals and amino acid homochirality is not complete. Mammals de novo synthesize most amino acids with l‐configuration, but serine and aspartate are converted from l‐ to d‐configuration by endogenous ...
Jumpei Sasabe   +4 more
wiley   +1 more source

Identification of Nonfermentative Bacilli [PDF]

open access: yesJournal of Clinical Microbiology, 1985
M. J. Pickett, G. L. Gilardi
openaire   +3 more sources

SULFOLIPID FROM VIRULENT TUBERCLE BACILLI [PDF]

open access: green, 1959
Gardner Middlebrook   +2 more
openalex   +1 more source

Harnessing Organometallic Au(III) Complexes as Precision Scaffolds for Next‐Generation Therapeutic and Imaging Agents

open access: yesChemBioChem, EarlyView.
Cyclometalated gold(III) complexes offer a versatile platform for selective biological interactions, including cysteine arylation, redox modulation, and enzyme inhibition. This review explores their roles in anticancer, antimicrobial, and protein modification strategies, highlighting their ability to disrupt metabolic pathways, modulate aquaporins, and
Sophie R. Thomas, Riccardo Bonsignore
wiley   +1 more source

Wetland restoration suppresses microbial carbon metabolism by altering keystone species interactions. [PDF]

open access: yesFront Microbiol
Zheng H   +9 more
europepmc   +1 more source

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