Results 211 to 220 of about 216,975 (333)

Synthesis and Evaluation of Trehalose‐Based Mertansine Warheads for BCG Delivery of Anti‐Cancer Agents

open access: yesChemBioChem, Accepted Article.
Non‐muscle invasive bladder cancer (NMIBC) accounts for 75% of bladder cancer cases, with Bacillus Calmette‐Guérin (BCG) immunotherapy as the gold standard for high‐risk patients. BCG elicits a robust immune response but is limited by adverse effects and resistance. To enhance its efficacy, we developed a trehalose‐based conjugation strategy, tethering
Michael Grimmeisen   +10 more
wiley   +1 more source

Epidemiological and Antimicrobial Resistance Trends in Bacterial Keratitis: A Hospital-Based 10-Year Study (2014-2024). [PDF]

open access: yesMicroorganisms
Shi Q   +11 more
europepmc   +1 more source

STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI [PDF]

open access: bronze, 1945
Walther F. Goebel   +2 more
openalex   +1 more source

Engineering Substrate Acceptance of Resveratrol O‐Methyltransferase from Vitis vinifera for the Selective Synthesis of O‐Methyl Protected Biobased Hydroxystyrenes

open access: yesChemCatChem, EarlyView.
Reaction sequence for the synthesis of methylated products through enzymatic decarboxylation of bio‐based hydroxycinnamic acids and subsequent direct methylation of the resulting styrene intermediates without any further isolation and purification steps.
Kamela Myrtollari   +6 more
wiley   +1 more source

Shifting the Substrate Scope of an Ene/Yne‐Reductase by Loop Engineering

open access: yesChemCatChem, EarlyView.
A flexible active‐site loop that is involved in shaping the substrate and product cleft as well as the active‐site pocket was identified for the MDR‐related ene/yne‐reductase CaeEnR1 from Cyclocybe aegerita. Double mutations of this loop showed an up to 20‐fold increase in conversion rates toward cinnamaldehyde‐like substrates and a 2‐fold increase in ...
Dominik Karrer   +7 more
wiley   +1 more source

Defining the cultured and uncultured bacterial fractions in Cannabis seeds. [PDF]

open access: yesEnviron Microbiome
Lobato C   +3 more
europepmc   +1 more source

Efficient Singlet Oxygen Monitoring in Aqueous Media Comprising a Polymer‐embedded Eu3+‐Complex

open access: yesChemistry – A European Journal, EarlyView.
A singlet dioxygen (1O2) sensitive Eu(III) complex embedded in polymer nanoparticles efficiently detects 1O2 in aqueous media by a remarkable increase in Eu3+ luminescence. These particles also adhere to bacteria surfaces, where the cells appear brightly stained in the presence of 1O2 enabling spectroscopic evaluation and easy detection under the ...
Daniel K. Dinga   +3 more
wiley   +1 more source

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