Results 231 to 240 of about 144,759 (285)

Defining the Intestinal eCBome and Oxylipin Signaling Systems in a TDP‐43 Mouse Model of Frontotemporal Dementia

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
TDP‐43 overexpressing mice, a genetic model of frontotemporal dementia, exhibit dramatic changes in their small intestinal endocannabinoidome members, in terms of both altered concentrations of lipid mediators and expression of some of their receptors (Cnr1, Gpr119, Gpr55, Pparg) and metabolic enzymes (Napepld, Faah). Also, the levels of some oxylipins
Hayatte‐Dounia Mir   +9 more
wiley   +1 more source

Lysogenic control of Bacillus subtilis morphology and fitness by Spbetavirus phi3T. [PDF]

open access: yesCommun Biol
Floccari VA   +10 more
europepmc   +1 more source

<i>Bacillus subtilis</i> in defense mode: Switch-like adaptations to protistan predation. [PDF]

open access: yesProc Natl Acad Sci U S A
van Gestel J   +6 more
europepmc   +1 more source

Design eines aus der Fettsäuresynthase der Maus abgeleiteten Multienzyms für die kompartimentierte chemo‐enzymatische Synthese von 2‐Pyron‐Polyketiden

open access: yesAngewandte Chemie, Volume 138, Issue 2, 9 January 2026.
Die 4‐Cumarate‐Ligase (4CL1) aus Piper methysticum wurde mit einer nicht‐reduzierenden murinen Fettsäuresynthase verknüpft. Eine direkte Acylierung des ACP durch 4CL1 wurde beobachtet. Die Ketosynthase (KS) wurde so verändert, dass sie das nicht‐kanonische Zimtsäure‐Substrat akzeptiert.
Felix Lehmann   +3 more
wiley   +1 more source

Design of a Multienzyme Derived from Mouse Fatty Acid Synthase for the Compartmentalized Production of 2‐Pyrone Polyketides

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 2, 9 January 2026.
A multienzyme was formed and evaluated by covalently linking 4‐coumarate ligase (4CL1) from Piper methysticum to a non‐reducing murine fatty acid synthase. 4CL1 acylates the acyl carrier protein (ACP). The ketosynthase (KS) was engineered to accept the non‐native cinnamoyl substrate, which is elongated by malonyl‐CoA loaded via the malonyl‐acetyl ...
Felix Lehmann   +3 more
wiley   +1 more source

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