Results 61 to 70 of about 317,433 (258)

Thermal Shifts Dominate Single‐Gene Responses to Transcription‐Targeting Antibiotics

Advanced Science, EarlyView.
Thermal shifts reshape bacterial responses to transcription‐targeting antibiotics. In E. coli, temperature can dominate antibiotic‐induced genome‐wide expression, particularly outside 30°C–39°C, through changes in adenosine triphosphate (ATP), nucleoid organization, and drug‐target engagement.
Rahul Jagadeesan, Amir M. Arsh, Vatsala Chauhan, Suchintak Dash, Pooja Ravaria, Andre S. Ribeiro   +5 more
wiley   +1 more source

The Potential of Self‐Maintainable Living Materials

Advanced Science, EarlyView.
Self‐maintainable living materials are presented as the next generation of bioadaptive systems, integrating continuous sensing, decision‐making, response, self‐repair, and adaptation in a closed‐loop framework. This review highlights the design principles and emerging technologies that enable autonomous, long‐term functionality for future regenerative ...
Mohammadsadegh Nadimifar, Tatiane Eufrásio‐da‐Silva, Lidia Maeso, Gorka Orive, Alireza Dolatshahi‐Pirouz   +4 more
wiley   +1 more source

Bacteria‐Derived 1‐Allylpiperazine Alleviates Symptoms of Parkinson's Disease Model by Promoting Autophagy

Advanced Science, EarlyView.
Parkinson's disease currently has no disease‐modifying therapies. In Caenorhabditis elegans, Escherichia coli E8 alleviates α‐synuclein‐provoked PD‐related defects through its bioactive metabolite 1‐ALPP, which combats PD by triggering AMPK/mTOR/HLH‐30‐dependent autophagy and suppressing α‐synuclein LLPS‐mediated fibrillization.
Mingqin Qu, Xinyuan Zhang, Xinyi Chen, Jiaxin Shi, Meng Xu, Fuhao Wang, Jinling Lv, Jiaman Sun, Weiyi Niu, Zihan Liu, Li Li, Fufeng Liu, Xiangming Wang   +12 more
wiley   +1 more source

The efficacy of bioproduct of Bacillus spp. on mycelium growth and controlling green mold disease of Ganoderma lucidum [PDF]

Songklanakarin Journal of Science and Technology (SJST)
This research aimed to study the potential of bioproduct of Bacillus spp. on promoting mycelial growth and controlling green mold disease caused by Trichoderma velutinum in Ganoderma lucidum. The antagonistic native Bacillus three isolates via Bacillus
Wiparat Noochaichaw, Patcharaporn Vanichpakorn, Pornsil Seephueak   +2 more
doaj  

The mechanism of Bacillus subtilis to guarantee the safe utilization of brackish water by improving soil physical properties and cotton production

Agricultural Water Management
Although brackish water (BW) irrigation alleviates freshwater (FW) scarcity in arid regions, it risks soil salinization, deterioration of soil physical properties, and productivity decline.
Yanpeng Bi, Beibei Zhou, Peiqi Ren, Shaoxiong Yao, Xiaopeng Chen, Xiaolong Yang, Piaohua Yu, Manli Duan   +7 more
doaj   +1 more source

Porphyrin‐Based Porous Materials for Antibacterial Applications

Advanced Science, EarlyView.
Porphyrin‐based porous materials have excellent photophysical properties and tunable structures for high‐efficiency antibacterial therapy. This review comprehensively discusses the structural design strategies and synthetic pathways of the four main types of porphyrin‐based porous materials, summarizes their cross‐domain antimicrobial applications, and
Xiao‐Xue Liang, Xin Li, Ying Xiong, Xin Wang, Ying‐Wei Yang   +4 more
wiley   +1 more source

How to change the oligomeric state of a circular protein assembly: switch from 11-subunit to 12-subunit TRAP suggests a general mechanism [PDF]

, 2011
Many critical cellular functions are performed by multisubunit circular protein oligomers whose internal geometry has evolved to meet functional requirements.
Antson, Alfred A, Antson, A., Merlino, N., Natalie Merlino, Chen, Chao-Sheng, Guy G. Dodson, Merlino, Natalie, Alfred A Antson, Dodson, Guy G, Shevtsov, Mikhail B, Dodson, G., Paul Gollnick, Gollnick, Paul, Alfred A. Antson, Shevtsov, Misha, Chao-Sheng Chen, Smits, Callum, Mikhail B Shevtsov, Smits, C., Callum Smits, Mikhail B. Shevtsov, Guy G Dodson, Gollnick, P., Chen, C., Antson Alfred A., Shevtsov Mikhail B., Merlino Natalie, Gollnick Paul, Dodson Guy G., Smits Callum, Chen Chao-Sheng   +30 more
core   +2 more sources

Semi‐Artificial Photosynthesis Enables Light‐Driven Biomanufacturing in Non‐Photosynthetic Bacteria

Advanced Science, EarlyView.
A non‐invasive strategy exploits endogenous H2S metabolism in B. subtilis to drive in situ CdS biomineralization, enabling tight bio‐abiotic contact without genetic modification. Light harvested by the biomineralized nanoparticles powers NADPH regeneration, elevating 2’‐fucosyllactose and surfactin titres two‐ to three‐fold.
Jie Zheng, Anqi Tong, Wenxin Li, Meng Qiao, Yang Gu, Muhammad Sohail, Shan He, Sheng Yang, Xing Zhang   +8 more
wiley   +1 more source

Characterization of PksD and PksG in Bacillus subtilis [PDF]

, 2006
Polyketides are a diverse class of natural products that have a wide variety of pharmacological applications. Polyketides are biosynthesized by modular polyketide synthases in a very similar fashion to that of fatty acids.
Mukherjee, Sriparna, NC DOCKS at The University of North Carolina at Greensboro   +1 more
core  

The Interplay Between Molybdopterin Synthase and Metal Metabolism Contributes to Pathogenicity in Acinetobacter baumannii

Advanced Science, EarlyView.
Pathogenic Acinetobacter baumannii scavenges metal ions as nutritional elements to survive within the host. This study demonstrates that molybdopterin synthase is essential for pathogenesis and full virulence during infection. Molybdopterin synthase subunit MoaE constitutes an intrinsically disordered C‐terminal histidine rich tail, which mediates ...
Min Jiao, Wenbo He, Zhenlin Ouyang, Ruochen Wang, Jiaxin Zhang, Xin Liu, Yiting Jing, Qinyue Yu, Xiaoyu He, Qian Qin, Litao Guo, Peter M. Hwang, Fang Zheng, Yurong Wen   +13 more
wiley   +1 more source