Results 91 to 100 of about 569,561 (310)

The prediction and back analysis of excavation behaviour in Oxford Clay. [PDF]

open access: yes, 1996
The work described in this thesis involved the prediction and back-analysis of ground movements and pore water pressures around a temporary excavation, lOm deep, 105m long and 35m wide (50m long and lOm wide at its base) in the heavily overconsolidated
Pierpoint, Nicholas David   +1 more
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

I'm going to fail! Acute cognitive performance anxiety increases threat-interference and impairs WM performance.

open access: yesPLoS ONE, 2019
Stress can impair cognitive performance, as commonly observed in cognitive performance anxiety (CPA; e.g., test anxiety). Cognitive theories indicate that stress impairs performance by increasing attention to negative thoughts, a phenomenon also known as
Angelos Angelidis   +4 more
doaj   +1 more source

Hardening rate under reverse loading in 316 L : Back stress and effective stress evolutions

open access: yes, 2001
The Bauschinger effect has been investigated in a low stacking fault energy f.c.c. alloy. Reverse hardening rate is discussed in terms of internal stresses evolutions as a function of reverse straining.
X. Feaugas, C. Guillemer-Neel, C. Gaudin
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

The effect of physiotherapy on anxiety, depression, and stress in chronic low back pain

open access: yesPublic Health of Indonesia
Background: Chronic low back pain has an impact on the patient’s life socially,financially, and psychologically, and little data is dealing with the effect of physiotherapy on improving this psychological burden.
Mustafa F. Abbas   +2 more
doaj   +1 more source

Assessment of residual stress using thermoelastic stress analysis

open access: yes, 2011
The work described in this thesis considers the application of thermoelastic stress analysis (TSA) to theassessment of residual stresses in metallic materials. Residual stresses exist within almost all engineeringcomponents and structures.
Robinson, Andrew Ferrand
core  

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

Effect of Radial Offset Between Welded Back to Back Elbows on Their C2 Stress Index

open access: yes, 2010
Pipe bends and elbows in process and power plant piping systems are sometimes added to provide additional flexibility along with their primary function of changing the direction of fluid flow.
W. Reinhardt, R. Balakrishnan
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

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