Results 101 to 110 of about 2,608,665 (304)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
The effect of physiotherapy on anxiety, depression, and stress in chronic low back pain
Public Health of IndonesiaBackground: Chronic low back pain has an impact on the patient’s life socially,financially, and psychologically, and little data is dealing with the effect of physiotherapy on improving this psychological burden.
Mustafa F. Abbas +2 more
doaj +1 more source
A constitutive model with damage for high temperature superalloys [PDF]
A unified constitutive model is searched for that is applicable for high temperature superalloys used in modern gas turbines. Two unified inelastic state variable constitutive models were evaluated for use with the damage parameter proposed by Kachanov ...
Sherwood, J. A., Stouffer, D. C.
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
, 1985 Analytical and experimental work were combined to develop a stress model to determine the temperature profile which will yield a satisfactory web. A thermal model of the web will be used to determine the thermal configuration which will yield the desired
Mcdonald, R. R.
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Potential of oil-lubricated cylindrical plastic gears
Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2018 Bending strength of injection molded polyacetal test gears is investigated in back-to-back testing using oil-lubrication. To validate state of the art calculation methods, tooth geometries with a variable number of teeth are investigated, maintaining a ...
Christian HASL +4 more
doaj +1 more source
Metric fluctuations of an evaporating black hole from back reaction of stress tensor fluctuations
, 2007 This paper delineates the first steps in a systematic quantitative study of the spacetime fluctuations induced by quantum fields in an evaporating black hole under the stochastic gravity program.
A. H. Zemanian +18 more
core +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source